Výsledky vyhledávání - "Fred Tonelli"

Use of Enzyme Inhibitors to Evaluate the Conversion Pathways of Ester and Amide Prodrugs: A Case Study Example with the Prodrug Ceftobiprole Medocaril

Autor: Brian W. Ogilvie, Andrew Parkinson, Fred Tonelli, Etsuko Usuki, Anne Schmitt-Hoffmann, Dawn Baumgardner, Jennifer Skibbe, Mark D. Johnson, Gary Eichenbaum, Jeff Holsapple

Publikováno v: Journal of Pharmaceutical Sciences. 101:1242-1252

An approach was developed that uses enzyme inhibitors to support the assessment of the pathways that are responsible for the conversion of intravenously administered ester and amide prodrugs in different biological matrices. The methodology was appli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c743befce736f146e5a7acc44eef6e39
https://doi.org/10.1002/jps.22816

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Akademický článek

Injectable anti-malarials revisited: discovery and development of new agents to protect against malaria.

Autor: Macintyre, Fiona¹, Ramachandruni, Hanu¹, Burrows, Jeremy N.¹, Holm, René^2,3, Thomas, Anna¹, Möhrle, Jörg J.¹, Duparc, Stephan¹, Hooft van Huijsduijnen, Rob¹, Greenwood, Brian⁴, Gutteridge, Winston E.¹, Wells, Timothy N. C.¹ awellst@mmv.org, Kaszubska, Wiweka¹

Publikováno v: Malaria Journal. 11/1/2018, Vol. 17 Issue 1, pN.PAG-N.PAG. 1p. 1 Diagram, 3 Charts.

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Akademický článek

Innovative Early Development Regulatory Approaches: expIND, expCTA, Microdosing.

Autor: Robinson, W. T.

Publikováno v: Clinical Pharmacology & Therapeutics; Feb2008, Vol. 83 Issue 2, p358-360, 3p, 1 Chart

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Akademický článek

Bioanalytical methods validation: A critique of the proposed FDA guidance.

Autor: Hill, H.

Publikováno v: Chromatographia; Jan2000 Supplement, Vol. 52, pS65-S69, 1p

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