Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Fred R., Miller"'
Autor:
Guojun Wu, Fred R. Miller, David H. Gorski, Wei Chen, Yongzhong Zhao, Bin Zhang, Cecilia L. Speyer, Fanyan Meng
Many epithelial–mesenchymal transition (EMT)–promoting transcription factors have been implicated in tumorigenesis and metastasis as well as chemoresistance of cancer. However, the underlying mechanisms mediating these processes are unclear. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b00244b70578fcd261279f7628b44859
https://doi.org/10.1158/0008-5472.c.6505979
https://doi.org/10.1158/0008-5472.c.6505979
Autor:
Guojun Wu, Fred R. Miller, David H. Gorski, Wei Chen, Yongzhong Zhao, Bin Zhang, Cecilia L. Speyer, Fanyan Meng
Supplementary Figures 1-8. Supplementary Figure 1: EMT promoting transcription factors induce stemness characteristics in mammary epithelial cells. Supplementary Figure 2: The role of Foxq1 in drug resistance, mammosphere formation and tumor initiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff8d30bf2e5c71a18e3b669fa81c9de
https://doi.org/10.1158/0008-5472.22402064
https://doi.org/10.1158/0008-5472.22402064
Autor:
Guojun Wu, Fred R. Miller, David H. Gorski, Wei Chen, Yongzhong Zhao, Bin Zhang, Cecilia L. Speyer, Fanyan Meng
Supplementary Tables 1-5. Supplementary Table 1: Sequences of shRNAs used to knock down target genes Supplementary Table 2: Sequences of PCR primers used in RT-PCR and QRT-PCR Supplementary Table 3: Representative genes up- or down-regulated by Foxq1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f36d7198df253f034b140e14c922be
https://doi.org/10.1158/0008-5472.22402061.v1
https://doi.org/10.1158/0008-5472.22402061.v1
Autor:
Fanyan Meng, Haijun Zhang, Gang Liu, Bas Kreike, Wei Chen, Seema Sethi, Fred R. Miller, Guojun Wu
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 5, Pp 472-482 (2011)
p38γ MAPK, one of the four members of p38 mitogen-activated protein kinases (MAPKs), has previously been shown to harbor oncogenic functions. However, the biologic function of p38γ MAPK in breast cancer has not been well defined. In this study, we
Externí odkaz:
https://doaj.org/article/f64683124ed74c399022c955c5091dd7
Autor:
Malathi Banda, Cecilia L Speyer, Sara N Semma, Kingsley O Osuala, Nicole Kounalakis, Keila E Torres Torres, Nicola J Barnard, Hyunjin J Kim, Bonnie F Sloane, Fred R Miller, James S Goydos, David H Gorski
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e81126 (2014)
TNBC is an aggressive breast cancer subtype that does not express hormone receptors (estrogen and progesterone receptors, ER and PR) or amplified human epidermal growth factor receptor type 2 (HER2), and there currently exist no targeted therapies ef
Externí odkaz:
https://doaj.org/article/772de355c36c49839ebb197834394e27
Autor:
Fred R. Miller, Cecilia L. Speyer, Guojun Wu, Yongzhong Zhao, Wei Chen, Fanyan Meng, David H. Gorski, Bin Zhang
Publikováno v:
Cancer Research. 75:584-593
Many epithelial–mesenchymal transition (EMT)–promoting transcription factors have been implicated in tumorigenesis and metastasis as well as chemoresistance of cancer. However, the underlying mechanisms mediating these processes are unclear. Here
Autor:
Edi Levi, Robert Kilkuskie, Fred R. Miller, Liyue Zhang, Scott D. Larsen, Arun K. Rishi, Anil Wali, Wenjuan Wu, Debra J. Bevis, Lisa Polin, Vineshkumar Thidil Puliyappadamba, Russell L. Finley
Publikováno v:
Journal of Biological Chemistry. 286:38000-38017
CARP-1/CCAR1, a perinuclear phosphoprotein, is a regulator of cell growth and apoptosis signaling. Although CARP-1 is a regulator of chemotherapy-dependent apoptosis, it is also a part of the NF-κB proteome and a co-activator of steroid/thyroid nucl
Autor:
Guojun Wu, Fred R. Miller, Bin Zhang, Fanyan Meng, Gang Liu, Haijun Zhang, Stephen P. Ethier, Feng Wu, Jun Zhu
Publikováno v:
Cancer Research. 71:1292-1301
Epithelial–mesenchymal transition (EMT) promotes cancer invasion and metastasis, but the integrative mechanisms that coordinate these processes are incompletely understood. In this study, we used a cross-species expression profiling strategy in met
Publikováno v:
International Journal of Cancer. 124:2813-2828
The MCF10A human breast epithelial cell lineage includes the benign MCF10A cells, premalignant cells (MCF10AT, MCF10ATG3B) and malignant MCF10CA1a tumor cells. The premalignant and tumor cells recapitulate the progressive alterations associated with