Výsledky vyhledávání - "Fred Kolling IV"

Hydroxymethylation alterations in progenitor-like cell types of pediatric central nervous system tumors are associated with cell type-specific transcriptional changes

Autor: Min Kyung Lee, Nasim Azizgolshani, Ze Zhang, Laurent Perreard, Fred Kolling IV, Lananh Nguyen, George Zanazzi, Lucas Salas, Brock Christensen

Although intratumoral heterogeneity has been established in pediatric central nervous system tumors, epigenomic alterations at the cell type level have largely remained unresolved. To identify cell type-specific alterations to cytosine modifications

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::330df0e5f6e491c04ac60d7ec42ae46d
https://doi.org/10.21203/rs.3.rs-2517758/v1

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Tumor type and cell type-specific gene expression alterations in diverse pediatric central nervous system tumors identified using single nuclei RNA-seq

Autor: Min Kyung Lee, Nasim Azizgolshani, Joshua Shapiro, Lananh Nguyen, Fred Kolling IV, George Zanazzi, Hildredth Frost, Brock Christensen

Central nervous system (CNS) tumors are the leading cause of pediatric cancer death, and these patients have an increased risk for developing secondary neoplasms. Due to the low prevalence of pediatric CNS tumors, major advances in targeted therapies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::560067e65ff3e648acac9a656a69c341
https://doi.org/10.21203/rs.3.rs-2517703/v1

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