Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Fred J Hendler"'
Publikováno v:
Ethics & Human Research
With the rapid spread of SARS‐CoV2 has come a rapid proliferation of clinical research studies, resulting in considerable strain on research ethics committees (RECS), which need to review study proposals. RECs are pressured to move through the revi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fceb3678eab621d265ef0fd7555a73f
https://doi.org/10.1002/eahr.500104
https://doi.org/10.1002/eahr.500104
Publikováno v:
International Journal of Cancer. 82:377-384
We established a new syngeneic murine model of oral squamous-cell carcinoma (SCC) to analyze the potential role of immune recognition determinants in the early development of oral cancer. In this study, we examined whether SCC that undergo transforma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12fa2a379ad48be4bda6ac50603b1d0b
https://doi.org/10.1002/(sici)1097-0215(19990730)82:3<377::aid-ijc11>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19990730)82:3<377::aid-ijc11>3.0.co
Publikováno v:
Cancer Control. 6:1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c3d69099be1181e254bf0674d96d769
https://doi.org/10.1177/107327489900600414
https://doi.org/10.1177/107327489900600414
Publikováno v:
Oncogene. 15:1161-1170
Our previous reports have shown that two thirds of 4-nitroquinoline-1-oxide (4NQO)-induced murine oral squamous cell carcinomas (SCC) have Hras1 mutations. Loss of heterozygosity (LOH) involving the distal portion of chromosome (Chr) 7 occurred in ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63780d05aa3ea343c2d506a661e18c7b
https://doi.org/10.1038/sj.onc.1201269
https://doi.org/10.1038/sj.onc.1201269
Publikováno v:
Molecular Carcinogenesis. 19:8-16
We have previously shown that all CBA/J mice exposed to 4-nitroquinoline-1-oxide (4NQO) eventually develop oral cavity squamous cell carcinomas, and two-thirds of these tumors have Ha-ras-1 (Hras1) point mutations at codon 12. Half of the tumors with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6eee68d0b581f9540a06548ef2c5ddd
https://doi.org/10.1002/(sici)1098-2744(199705)19:1<8::aid-mc2>3.0.co
https://doi.org/10.1002/(sici)1098-2744(199705)19:1<8::aid-mc2>3.0.co
Publikováno v:
Genomics. 38:58-71
Although occasional DNA polymorphisms have been observed in inbred mice, CBA/J and C3H/HeN mice have two microsatellite alleles at over 1/3 of microsatellite loci tested. Since DNA polymorphisms were not detected in DBA/2J, C57BL/6J, and BALB/cJ, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586609c8f2f7aa8204b016df6d05a122
https://doi.org/10.1006/geno.1996.0592
https://doi.org/10.1006/geno.1996.0592
Autor:
Michael Leonberger, Brian L. Hawkins, Douglas M. Ackermann, Serge A. Martinez, Briana W. Heniford, Fred J. Hendler
Publikováno v:
Head & Neck. 16:424-432
Background. A murine model of oral cavity carcinogenesis is needed to study the molecular aspects of malignant transformation. 4-Nitroquinoline-1-oxide (4NQO), a water-soluble carcinogen, produces squamous cell carcinoma in rodents. Protocols were de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ea43ce0f2216e2ece047c5bce6dee5
https://doi.org/10.1002/hed.2880160506
https://doi.org/10.1002/hed.2880160506
Autor:
Carter Van Waes, Lyon L. Gleich, Jian Dong, Robert J. Bohinski, Ya-Qin Li, Fred J. Hendler, Peter J. Stambrook
Publikováno v:
Cancer gene therapy. 10(2)
The Flt3 ligand (Flt3-L) manifests antitumor activity, presumably due to its capacity to recruit dendritic cells and cause their proliferation. To assess whether local production of Flt3-L can mediate a "distant bystander" effect, murine B4B8 squamou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5174870790d5e2d26ce3d108be45758
https://pubmed.ncbi.nlm.nih.gov/12536197
https://pubmed.ncbi.nlm.nih.gov/12536197
Publikováno v:
Otolaryngology–Head and Neck Surgery. 117
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc949df40b90b7a22c4186bcb2c0675
https://doi.org/10.1016/s0194-59989780223-9
https://doi.org/10.1016/s0194-59989780223-9
Autor:
Fred J. Hendler
Publikováno v:
The American Journal of the Medical Sciences. 293:332-347
Benign breast disease affects almost all women, although only one out of 11 will eventually develop breast cancer. Fibrocystic disease or benign breast mastopathies have been associated with an increased propensity to progress to malignancy. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8028b9d55fcaf2db14cbdfc17e3581b
https://doi.org/10.1097/00000441-198705000-00010
https://doi.org/10.1097/00000441-198705000-00010