Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Fred Fandrich"'
Autor:
Paloma Riquelme, Jan Haarer, Anja Kammler, Lisa Walter, Stefan Tomiuk, Norbert Ahrens, Anja K. Wege, Ivan Goecze, Daniel Zecher, Bernhard Banas, Rainer Spang, Fred Fändrich, Manfred B. Lutz, Birgit Sawitzki, Hans J. Schlitt, Jordi Ochando, Edward K. Geissler, James A. Hutchinson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Regulatory macrophages (Mreg) can directly suppress T effector cell responses. Here the authors show that human Mreg also elicit TIGIT+ regulatory T cells by integrating multiple differentiation signals, and that donor Mreg-induced recipient Tregs ma
Externí odkaz:
https://doaj.org/article/bde1072b3b4842efb0f1df25fc4a3f9e
Autor:
Hendrik Ungefroren, Ayman Hyder, Hebke Hinz, Stephanie Groth, Hans Lange, Karim M Fawzy El-Sayed, Sabrina Ehnert, Andreas K Nüssler, Fred Fändrich, Frank Gieseler
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118097 (2015)
Previous studies have shown that peripheral blood monocytes can be converted in vitro to a stem cell-like cell termed PCMO as evidenced by the re-expression of pluripotency-associated genes, transient proliferation, and the ability to adopt the pheno
Externí odkaz:
https://doaj.org/article/629b1bf9feaf4e47907b20977c4f7a77
Autor:
Christiane Broichhausen, Paloma Riquelme, Norbert Ahrens, Anja K Wege, Gudrun E Koehl, Hans J Schlitt, Bernhard Banas, Fred Fändrich, Edward K Geissler, James A Hutchinson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
A new cell-based medicinal product containing human regulatory macrophages, known as Mreg_UKR, has been developed and conforms to expectations of a therapeutic drug. Here, Mreg_UKR was subjected to pharmacokinetic, safety pharmacology, and toxicologi
Externí odkaz:
https://doaj.org/article/4d6ed0972d8c47da818a90fe9ed5644f
Autor:
Lars Hummitzsch, Karina Zitta, Rene Rusch, Jochen Cremer, Markus Steinfath, Justus Gross, Fred Fandrich, Rouven Berndt, Martin Albrecht
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Ischemia/reperfusion- (I/R-) induced organ damage represents one of the main causes of death worldwide, and new strategies to reduce I/R injury are urgently needed. We have shown that programmable cells of monocytic origin (PCMO) respond to I/R with
Externí odkaz:
https://doaj.org/article/0dafe3c937be4cd0ba5f112f32bda266
Autor:
Karina Zitta, Lars Hummitzsch, Frank Lichte, Fred Fändrich, Markus Steinfath, Christine Eimer, Sebastian Kapahnke, Matthias Buerger, Katharina Hess, Melanie Rusch, Rene Rusch, Rouven Berndt, Martin Albrecht
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background Macrophages are involved in tissue homeostasis, angiogenesis and immunomodulation. Proangiogenic and anti-inflammatory macrophages (regulatory macrophages, Mreg) can be differentiated in-vitro from CD14+ monocytes by using a defin
Externí odkaz:
https://doaj.org/article/51f12bd03bc74df9971446b0755322a3
Autor:
Terawan Agus Putranto, Denny Irwansyah, Nurhadiyanta Nurhadiyanta, Endra Tri Prabowo, Djoko Wibisono, Nyoto Widyo Astoro, Fred Fandrich, Taruna Ikrar, Martina Lily Yana, Yudo Rantung
Publikováno v:
Bali Medical Journal, Vol 8, Iss 3, Pp 726-732 (2019)
Introduction: Systemic Lupus Erythematosus (SLE) has been quite an enigma in medicine. The possibility of the host own defense mechanism attacking itself is still quite difficult to understand. Patients who suffer from this disease tend to have a pro
Autor:
Martin Albrecht, Lars Hummitzsch, Rene Rusch, Katharina Heß, Markus Steinfath, Jochen Cremer, Frank Lichte, Fred Fändrich, Rouven Berndt, Karina Zitta
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background Large extracellular vesicles (L-EV) with a diameter between 1 and 10 µm are released by various cell types. L-EV contain and transport active molecules which are crucially involved in cell to cell communication. We have shown tha
Externí odkaz:
https://doaj.org/article/7907c0c1082f45798af3193f2fbfb373
Autor:
Monika, Olempska, Patricia Alice, Eisenach, Ole, Ammerpohl, Hendrik, Ungefroren, Fred, Fandrich, Holger, Kalthoff
Publikováno v:
Hepatobiliarypancreatic diseases international : HBPD INT. 6(1)
Cancer of the pancreas is the fourth leading cause of cancer death in industrialized countries. In malignancy, actively proliferating cells may be effectively targeted and killed by anti-cancer therapies, but stem cells may survive and support re-gro
Autor:
Manfred Wehrmann, Christoph Köhle, Fotios Petroktistis, Michael J. Sessler, C. H. Gleiter, Fred Fandrich, Almut Grenz, Martin Schenk, Hartmut Osswald, Detlef Baier
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 317(2)
Several previous studies have demonstrated a beneficial effect of the adenosine receptor (AdoR) antagonist theophylline in different forms of acute renal failure in laboratory animals and in humans. Therefore, we wanted to test whether theophylline c
Autor:
Maren Ruhnke, Andreas K Nussler, Hendrik Ungefroren, Jan G Hengstler, Bernd Kremer, Wolfgang Hoeckh, Thomas Gottwald, Peter Heeckt, Fred Fandrich
Publikováno v:
Transplantation; May2005, Vol. 79 Issue 9, p1097-1103, 7p