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Treating haemophilia A with recombinant blood factors: a comparison

Autor: Natalya M. Ananyeva, Alexey V. Khrenov, Evgueni L. Saenko, Robert Summers, Andrey Sarafanov, Fred Darr

Publikováno v: Expert Opinion on Pharmacotherapy. 5:1061-1070

The mainstay in the treatment of haemophilia A is replacement therapy with repeated infusions of plasma-derived Factor VIII (FVIII) concentrates or recombinant FVIII products. While modern plasma-derived FVIII concentrates have an excellent safety pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d810c81eb5f2a98aa48b4ebc4fa52f
https://doi.org/10.1517/14656566.5.5.1061

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Pharmacokinetics of von Willebrand factor and factor VIIIC in patients with severe von Willebrand disease (type 3 VWD): estimation of the rate of factor VIIIC synthesis

Autor: Gilbert C. White, Arthur R. Thompson, Doris Menache, Craig M. Kessler, Jeanne M. Lusher, Amy D. Shapiro, Fred Darr, Joan Cox Gill, David L. Aronson, Robert R. Montgomery, Pradyumna D. Phatak

Publikováno v: British Journal of Haematology. 94:740-745

Nine patients (10 infusions) with a confirmed diagnosis of type 3 VWD were infused with von Willebrand factor (human), a preparation of von Willebrand factor (VWF) with a very low factor VIII content. Each patient was infused with one dose of approxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc10de3a80b097dda17cff0bb37cea55
https://doi.org/10.1046/j.1365-2141.1996.d01-1860.x

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Rapid infusion of intravenous immunoglobulin in patients with neuromuscular diseases

Autor: Edward D. Gomperts, Fred Darr

Publikováno v: Neurology. 58:1444-1444

To the Editor: Grillo et al. reviewed the use of rapid infusion of IV immune globulin in patients with neuromuscular disorders.1 Their abstract and discussion claim the safety and convenience of this practice in their population of patients, and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a5e3f2c03176683c71d2022716a5810
https://doi.org/10.1212/wnl.58.9.1444

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THYMOSIN IN THE EARLY DIAGNOSIS AND TREATMENT OF HIGH RISK HOMOSEXUALS AND HEMOPHILIACS WITH AIDS-LIKE IMMUNE DYSFUNCTION

Autor: Gary L. Simon, Paul H. Naylor, Marcelo B. Sztein, Craig M. Kessler, Fred Darr, Richard S. Schulof, Allan L. Goldstein, Paul R. McCurdy, Thomas J. Spira

Publikováno v: Annals of the New York Academy of Sciences. 437:88-97

The adnormal levels of thymosin alpha 1 in acquired immunodeficiency syndrome (AIDS) patients, depressed T-cell function, thymus pathology, and the restoration of T-cell function by thymosin fraction 5 (TF5) lend support to the hypothesis that the th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a757ab77be97f7de1f274146e1f0ce
https://doi.org/10.1111/j.1749-6632.1984.tb37125.x

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Clinical Implications of Positive Tests for Antibodies to Human Immunodeficiency Virus Type 1 in Asymptomatic Blood Donors

Autor: Susan F. Leitman, Harvey G. Klein, Jacqueline J. Melpolder, Elizabeth J. Read, Juan I. Esteban, Eileen M. Leonard, Liana Harvath, J. Wai-Kuo Shih, Regina Nealon, John Foy, Fred Darr, Harvey J. Alter

Publikováno v: New England Journal of Medicine. 321:917-924

Of 693,000 volunteer blood donors in Washington, D.C., who were screened for infection with human immunodeficiency virus type 1 (HIV-1) from July 1985 through December 1988, 284 tested positive on both enzyme immunoassay and Western blot assay. To de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2dbbdeef0bd1deb97b9dce74d2747f3
https://doi.org/10.1056/nejm198910053211401

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