Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Fred D. Ledley"'
Autor:
Naomi L. B. Wernick, Fred D. Ledley
Publikováno v:
Journal of Microbiology & Biology Education, Vol 21, Iss 1 (2020)
Most undergraduate students who leave STEM majors before graduation choose careers in business. This article argues that better integrating business opportunities and context into the STEM curriculum could advance STEM learning, motivate students to
Externí odkaz:
https://doaj.org/article/afb06e3ac6484a619fdaf274a23b0f0a
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 379-386 (2017)
The long path from initial research on oligonucleotide therapies to approval of antisense products is not unfamiliar. This lag resembles those encountered with monoclonal antibodies, gene therapies, and many biological targets and is consistent with
Externí odkaz:
https://doaj.org/article/2c32094cee494775baa8cebdc7ca99f0
Publikováno v:
Journal of Microbiology & Biology Education, Vol 15, Iss 2, Pp 268-276 (2014)
Biological thought increasingly recognizes the centrality of the genome in constituting and regulating processes ranging from cellular systems to ecology and evolution. In this paper, we ask whether genomics is similarly positioned as a core concept
Externí odkaz:
https://doaj.org/article/3cdf80ff5a1e4644947cce6d6a30e83e
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Objectives Pharmaceutical innovation can contribute to reducing the burden of disease in human populations. This research asks whether products approved by the US Food and Drug Administration (FDA) from 2010 to 2019 and expedited review programmes in
Externí odkaz:
https://doaj.org/article/1f0a1b5e40fd4860bb581d03b4a078ff
Autor:
R. Mark Adams, Mary Wang, Ana Maria Crane, Bridgette Brown, Gretchen J. Darlington, Fred D. Ledley
Publikováno v:
Cell Transplantation, Vol 4 (1995)
Despite reports of successful cryopreservation of primary human hepatocytes, existing methods do not produce sufficient recovery of viable cells to meet the needs of basic research or clinical trials of hepatocellular transplantation. We now describe
Externí odkaz:
https://doaj.org/article/672c855ac78b4da8bb255e4b40287b92
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283887 (2023)
Licenses of drug-related biotechnologies from academic institutions to commercial firms are intended to promote practical applications of public sector research and a return on government investments in biomedical science. This empirical study compar
Externí odkaz:
https://doaj.org/article/6954a759c8184384bac3a6692a00cd3d
Autor:
Ekaterina Galkina Cleary, Laura M McNamee, Skyler de Boer, Jeremy Holden, Liam Fitzgerald, Fred D Ledley
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0243813 (2021)
We compared the financial performance of 319 BIOTECH companies focused on developing therapeutics with IPOs from 1997-2016, to that of paired, non-biotech CONTROL companies with concurrent IPO dates. BIOTECH companies had a distinctly different finan
Externí odkaz:
https://doaj.org/article/f9e530faa4df411babc656bd54b0c721
Publikováno v:
JAMA Health Forum. 4:e230511
ImportanceGovernment and the pharmaceutical industry make substantive contributions to pharmaceutical innovation. This study compared the investments by the National Institutes of Health (NIH) and industry and estimated the cost basis for assessing t
Publikováno v:
Institute for New Economic Thinking Working Paper Series. :1-72
The discovery and development of new medicines classically involves a linear process of basic biomedical research to uncover potential targets for drug action, followed by applied, or translational, research to identify candidate products and establi
Publikováno v:
The Lancet Oncology. 21:755-757