Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Fred C. Olson"'
Autor:
Edward J. Massaro, Fred C. Olson
Publikováno v:
Teratology. 16:187-194
Methylmercury (MeHg: 5 mg Hg/kg maternal body weight) in 0.13 M NaCl, 0.01 M NaH2PO4-Na2HPO4, pH 7.4 (PBS) administered to gravid CFW mice on day 12, hour 6 (12(6)) of gestation induced a high incidence of cleft palate in fetuses examined on days 15(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ec717885abe5a2c9bd3ddd0c492385
https://doi.org/10.1002/tera.1420160213
https://doi.org/10.1002/tera.1420160213
Autor:
Fred C. Olson, Edward J. Massaro
Publikováno v:
Teratology. 22:155-166
Exposure to methylmercury (MeHg: 10 mg Hg/kg maternal body weight) on 12(6) (days hours) of gestation significantly delays palate closure in the Swiss Webster CFW mouse. The cAMP content and activity of adenyl cyclase and phosphodiesterase (PDE) were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21aa6e7bd4f24e15e0cfe1a4ac3c08e
https://doi.org/10.1002/tera.1420220204
https://doi.org/10.1002/tera.1420220204
Publikováno v:
European Journal of Cancer and Clinical Oncology. 18:167-176
The inherent toxicities of drug-free liposomes were compared. Positively charged liposomes were more toxic in vitro (chick heart cells) and in vivo (5-fold reduction in LD50 in mice) than neutral or negatively charged liposomes. Based on these findin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559b37d28684ed6508b42730ea73898d
https://doi.org/10.1016/0277-5379(82)90060-8
https://doi.org/10.1016/0277-5379(82)90060-8
Publikováno v:
Biochimica et biophysica acta. 557(1)
Liposomes of defined size and homogeneity have been prepared by sequential extrusion of the usual multilamellar vesicles through polycarbonate membranes. The process is easy, reproducible, produces no detectable degradation of the phospholipids, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab7ed4e0440dce74682d6d83ef33e8c
https://pubmed.ncbi.nlm.nih.gov/95096
https://pubmed.ncbi.nlm.nih.gov/95096
Autor:
Fred C. Olson, Edward J. Massaro
Publikováno v:
Toxicology and applied pharmacology. 39(2)
To investigate fetal uptake of methyl mercury (MeHg) during organogenesis, a single dose of MeHg (5 mg of Hg/kg), 100 μCi203 Hg/kg in 0.13 m NaCl, 0.01 m Na2HPO4, pH 7.4) was administered sc to pregnant Swiss-Webster CFW mice on Days 7 through 13 of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5a97569f56d2c4f23303ebed7a56d6
https://pubmed.ncbi.nlm.nih.gov/847755
https://pubmed.ncbi.nlm.nih.gov/847755
Autor:
Fred C. Olson, Eric Mayhew, Francis C. Szoka, W.J. Vail, Demetrios Papahadjopoulos, Timothy D. Heath
Publikováno v:
Biochimica et biophysica acta. 601(3)
Liposomes can be prepared by a combination of reverse phase evaporation and sequential extrusion through polycarbonate membranes. The vesicles have diameters in the range 0.05-0.5 micron and are mostly unilamellar as indicated by electon microscopy,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eed8cdca97f2160b3ebee2e30c7b2e3
https://pubmed.ncbi.nlm.nih.gov/6251878
https://pubmed.ncbi.nlm.nih.gov/6251878
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