Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Fred, Naider"'
Autor:
Fred Naider, Jeffrey M. Becker
Publikováno v:
Molecules, Vol 25, Iss 18, p 4272 (2020)
Work from our laboratories over the last 35 years that has focused on Ste2p, a G protein-coupled receptor (GPCR), and its tridecapeptide ligand α-factor is reviewed. Our work utilized the yeast Saccharomyces cerevisiae as a model system for understa
Externí odkaz:
https://doaj.org/article/db23c0f3373c4bc0931b1e2f2d1b0bdc
Publikováno v:
Bio-Protocol, Vol 6, Iss 22 (2016)
We describe an assay for determination of toxicity in S. cerevisiae involving spotting of a toxic peptide on a lawn of yeast cells. This assay may be generalized to determine toxicity of a variety of compounds by substituting a putative toxic compoun
Externí odkaz:
https://doaj.org/article/8da26034ef3f41fd802b962f84fe8070
Publikováno v:
Bio-Protocol, Vol 6, Iss 22 (2016)
We describe an assay for measuring the uptake of radioactive peptides into the yeast Saccharomyces cerevisiae. The methods presented here can be adapted to measure a variety of substrates transported into any bacterial or fungal cell via specific car
Externí odkaz:
https://doaj.org/article/e1cf6d860ad24a1fb881c0f2fa2a6cf0
Autor:
Naama Kessler, Lewis E. Kay, Suresh Kumar, Jacob Solanki, Leah S. Cohen, Sabine R. Akabayov, Fred Naider, Jacob Anglister
Publikováno v:
Journal of Biomolecular NMR. 74:681-693
Many proteins interact with their ligand proteins by recognition of short linear motifs that are often intrinsically disordered. These interactions are usually weak and are characterized by fast exchange. NMR spectroscopy is a powerful tool to study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60629cda9ed6a2b8c0772cb0224fe786
https://doi.org/10.1007/s10858-020-00340-y
https://doi.org/10.1007/s10858-020-00340-y
Publikováno v:
The FEBS journalReferences. 289(11)
The N-terminal segment of CCR5 contains four tyrosine residues, sulphation of two of which is essential for high-affinity binding to gp120. In the present study, the interactions of gp120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6fda616375c045acad1e9a1efcc0115
https://pubmed.ncbi.nlm.nih.gov/34921512
https://pubmed.ncbi.nlm.nih.gov/34921512
Publikováno v:
Biophys J
G-protein-coupled receptors (GPCRs) comprise a large superfamily of transmembrane receptors responsible for transducing responses to the binding of a wide variety of hormones, neurotransmitters, ions, and other small molecules. There is extensive evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b75a475eb11063f28bee326ef6374e
https://europepmc.org/articles/PMC8633717/
https://europepmc.org/articles/PMC8633717/
Autor:
Jeffrey M. Becker, Fred Naider
Publikováno v:
Molecules, Vol 25, Iss 4272, p 4272 (2020)
Molecules
Molecules
Work from our laboratories over the last 35 years that has focused on Ste2p, a G protein-coupled receptor (GPCR), and its tridecapeptide ligand α-factor is reviewed. Our work utilized the yeast Saccharomyces cerevisiae as a model system for understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45d0858019b76d6120c8bd41b459abd
https://www.mdpi.com/1420-3049/25/18/4272
https://www.mdpi.com/1420-3049/25/18/4272
Autor:
Lewis E. Kay, Jacob Anglister, Brandon Fridman, Naama Kessler, Fred Naider, Leah S. Cohen, Adi Moseri, Damir Sakhapov, David Bolton, Sabine R. Akabayov
Publikováno v:
The FEBS journalReferences. 288(5)
The N-terminal segment of the chemokine receptor Human CC chemokine receptor 5 (CCR5), Nt-CCR5, contains four tyrosine residues, Y3, Y10, Y14, and Y15. Sulfation of at least two of these tyrosine residues was found to be essential for high-affinity b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ad58b9be89d99a46f908ed3ae265e8
https://pubmed.ncbi.nlm.nih.gov/32814359
https://pubmed.ncbi.nlm.nih.gov/32814359
Publikováno v:
The FEBS Journal. 285:4296-4310
Infection by HIV-1 requires protein-protein interactions involving gp120, CD4 and CCR5. We have previously demonstrated that the transferred nuclear Overhauser effect (TRNOE), in combination with asymmetric deuteration of a protein and a peptide liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e6b8cb016949de4a10b8b0b08c1163
https://doi.org/10.1111/febs.14673
https://doi.org/10.1111/febs.14673