Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Fred, Fändrich"'
Autor:
Karina Zitta, Lars Hummitzsch, Frank Lichte, Fred Fändrich, Markus Steinfath, Christine Eimer, Sebastian Kapahnke, Matthias Buerger, Katharina Hess, Melanie Rusch, Rene Rusch, Rouven Berndt, Martin Albrecht
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background Macrophages are involved in tissue homeostasis, angiogenesis and immunomodulation. Proangiogenic and anti-inflammatory macrophages (regulatory macrophages, Mreg) can be differentiated in-vitro from CD14+ monocytes by using a defin
Externí odkaz:
https://doaj.org/article/51f12bd03bc74df9971446b0755322a3
Autor:
Martin Albrecht, Lars Hummitzsch, Rene Rusch, Katharina Heß, Markus Steinfath, Jochen Cremer, Frank Lichte, Fred Fändrich, Rouven Berndt, Karina Zitta
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background Large extracellular vesicles (L-EV) with a diameter between 1 and 10 µm are released by various cell types. L-EV contain and transport active molecules which are crucially involved in cell to cell communication. We have shown tha
Externí odkaz:
https://doaj.org/article/7907c0c1082f45798af3193f2fbfb373
Autor:
Paloma Riquelme, Jan Haarer, Anja Kammler, Lisa Walter, Stefan Tomiuk, Norbert Ahrens, Anja K. Wege, Ivan Goecze, Daniel Zecher, Bernhard Banas, Rainer Spang, Fred Fändrich, Manfred B. Lutz, Birgit Sawitzki, Hans J. Schlitt, Jordi Ochando, Edward K. Geissler, James A. Hutchinson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Regulatory macrophages (Mreg) can directly suppress T effector cell responses. Here the authors show that human Mreg also elicit TIGIT+ regulatory T cells by integrating multiple differentiation signals, and that donor Mreg-induced recipient Tregs ma
Externí odkaz:
https://doaj.org/article/bde1072b3b4842efb0f1df25fc4a3f9e
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Following a several-day incubation in medium containing IL-3 and M-CSF to generate a more plastic intermediate “reprogrammed multipotent cells of monocytic origin (RMCMO),” peripheral blood mononuclear cells (PBMCs) can be efficiently converted t
Externí odkaz:
https://doaj.org/article/a188fdc0dc1243e2b859778628433c65
Autor:
Hendrik Ungefroren, Ayman Hyder, Maren Schulze, Karim M. Fawzy El-Sayed, Evelin Grage-Griebenow, Andreas K. Nussler, Fred Fändrich
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Adult stem or programmable cells hold great promise in diseases in which damaged or nonfunctional cells need to be replaced. We have recently demonstrated that peripheral blood monocytes can be differentiated in vitro into cells resembling specialize
Externí odkaz:
https://doaj.org/article/f3953d4979ce4abd84d47202b5b14066
Autor:
Karina Zitta, Katharina Hess, Matthias Gruenewald, Fred Fändrich, Rouven Berndt, Lena Fritze, Matthias Lindner, Rene Rusch, Martin Albrecht, Lars Hummitzsch, Markus Steinfath, Patrick Vollertsen, Jonas Monnens
Publikováno v:
Basic Research in Cardiology
Remote ischemic preconditioning (RIPC) protects the heart against myocardial ischemia/reperfusion (I/R) injury and recent work also suggested chronic remote ischemic conditioning (cRIPC) for cardiovascular protection. Based on current knowledge that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80dc0c3f68c0dc3e67aecfcef4a1ca53
https://doi.org/10.1007/s00395-021-00901-8
https://doi.org/10.1007/s00395-021-00901-8
Autor:
Hendrik Ungefroren, Ayman Hyder, Hebke Hinz, Stephanie Groth, Hans Lange, Karim M Fawzy El-Sayed, Sabrina Ehnert, Andreas K Nüssler, Fred Fändrich, Frank Gieseler
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118097 (2015)
Previous studies have shown that peripheral blood monocytes can be converted in vitro to a stem cell-like cell termed PCMO as evidenced by the re-expression of pluripotency-associated genes, transient proliferation, and the ability to adopt the pheno
Externí odkaz:
https://doaj.org/article/629b1bf9feaf4e47907b20977c4f7a77
Autor:
Christiane Broichhausen, Paloma Riquelme, Norbert Ahrens, Anja K Wege, Gudrun E Koehl, Hans J Schlitt, Bernhard Banas, Fred Fändrich, Edward K Geissler, James A Hutchinson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
A new cell-based medicinal product containing human regulatory macrophages, known as Mreg_UKR, has been developed and conforms to expectations of a therapeutic drug. Here, Mreg_UKR was subjected to pharmacokinetic, safety pharmacology, and toxicologi
Externí odkaz:
https://doaj.org/article/4d6ed0972d8c47da818a90fe9ed5644f
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Following a several-day incubation in medium containing IL-3 and M-CSF to generate a more plastic intermediate “reprogrammed multipotent cells of monocytic origin (RMCMO),” peripheral blood mononuclear cells (PBMCs) can be efficiently converted t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cff0cd09556c7ef735bf7f6c27436e
https://doi.org/10.1155/2018/4271875
https://doi.org/10.1155/2018/4271875
Autor:
Rouven Berndt, Karina Zitta, Fred Fändrich, Martin Albrecht, Lars Hummitzsch, Jochen Cremer, Justus Gross, Markus Steinfath, Rene Rusch
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2019 (2019)
Stem Cells International, Vol 2019 (2019)
Ischemia/reperfusion- (I/R-) induced organ damage represents one of the main causes of death worldwide, and new strategies to reduce I/R injury are urgently needed. We have shown that programmable cells of monocytic origin (PCMO) respond to I/R with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009ba66f8196c491fdfa19dd36b51aa1
http://europepmc.org/articles/PMC6614961
http://europepmc.org/articles/PMC6614961