A single-cell mass cytometry-based atlas of the developing mouse brain.

Autor: Van Deusen AL; Department of Biology, College of Arts and Sciences, University of Virginia, Charlottesville, VA, USA.; Neuroscience Graduate Program, School of Medicine, University of Virginia, Charlottesville, VA, USA.; Department of Biomedical Engineering, School of Engineering, University of Virginia, Charlottesville, VA, USA., Kumar S; Department of Biology, College of Arts and Sciences, University of Virginia, Charlottesville, VA, USA.; Neuroscience Graduate Program, School of Medicine, University of Virginia, Charlottesville, VA, USA., Calhan OY; Department of Biology, College of Arts and Sciences, University of Virginia, Charlottesville, VA, USA., Goggin SM; Neuroscience Graduate Program, School of Medicine, University of Virginia, Charlottesville, VA, USA.; Department of Biomedical Engineering, School of Engineering, University of Virginia, Charlottesville, VA, USA., Shi J; Department of Biology, College of Arts and Sciences, University of Virginia, Charlottesville, VA, USA., Williams CM; Department of Biomedical Engineering, School of Engineering, University of Virginia, Charlottesville, VA, USA., Keeler AB; Department of Biology, College of Arts and Sciences, University of Virginia, Charlottesville, VA, USA., Fread KI; Department of Biomedical Engineering, School of Engineering, University of Virginia, Charlottesville, VA, USA., Gadani IC; Department of Biology, College of Arts and Sciences, University of Virginia, Charlottesville, VA, USA.; Neuroscience Graduate Program, School of Medicine, University of Virginia, Charlottesville, VA, USA., Deppmann CD; Department of Biology, College of Arts and Sciences, University of Virginia, Charlottesville, VA, USA. deppmann@virginia.edu.; Neuroscience Graduate Program, School of Medicine, University of Virginia, Charlottesville, VA, USA. deppmann@virginia.edu.; Department of Biomedical Engineering, School of Engineering, University of Virginia, Charlottesville, VA, USA. deppmann@virginia.edu.; Department of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA, USA. deppmann@virginia.edu.; Department of Cell Biology, School of Medicine, University of Virginia, Charlottesville, VA, USA. deppmann@virginia.edu.; Program in Fundamental Neuroscience, College of Arts and Sciences, University of Virginia, Charlottesville, VA, USA. deppmann@virginia.edu., Zunder ER; Neuroscience Graduate Program, School of Medicine, University of Virginia, Charlottesville, VA, USA. ezunder@virginia.edu.; Department of Biomedical Engineering, School of Engineering, University of Virginia, Charlottesville, VA, USA. ezunder@virginia.edu.; Program in Fundamental Neuroscience, College of Arts and Sciences, University of Virginia, Charlottesville, VA, USA. ezunder@virginia.edu.

Publikováno v: Nature neuroscience [Nat Neurosci] 2024 Dec 18. Date of Electronic Publication: 2024 Dec 18.

FLOW-MAP: a graph-based, force-directed layout algorithm for trajectory mapping in single-cell time course datasets.

Autor: Ko ME; Cancer Biology Program, Stanford School of Medicine, Stanford, CA, USA., Williams CM; Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.; Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA, USA., Fread KI; Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA., Goggin SM; Neuroscience Graduate Program, University of Virginia, Charlottesville, VA, USA., Rustagi RS; Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA., Fragiadakis GK; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA., Nolan GP; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA., Zunder ER; Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA. ezunder@virginia.edu.

Publikováno v: Nature protocols [Nat Protoc] 2020 Feb; Vol. 15 (2), pp. 398-420. Date of Electronic Publication: 2020 Jan 13.

Tom1 Modulates Binding of Tollip to Phosphatidylinositol 3-Phosphate via a Coupled Folding and Binding Mechanism.

Autor: Xiao S; Protein Signaling Domains Laboratory, Department of Biological Sciences, Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA., Brannon MK; Protein Signaling Domains Laboratory, Department of Biological Sciences, Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA., Zhao X; Protein Signaling Domains Laboratory, Department of Biological Sciences, Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA., Fread KI; Protein Signaling Domains Laboratory, Department of Biological Sciences, Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA., Ellena JF; Department of Chemistry and Biochemistry, University of Virginia, Charlottesville, VA 22904, USA., Bushweller JH; Department of Chemistry and Biochemistry, University of Virginia, Charlottesville, VA 22904, USA., Finkielstein CV; Integrated Cellular Responses Laboratory, Department of Biological Sciences, Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA., Armstrong GS; Departments of Chemistry and Biochemistry, University of Colorado at Boulder, Boulder, CO 80309, USA., Capelluto DGS; Protein Signaling Domains Laboratory, Department of Biological Sciences, Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA. Electronic address: capellut@vt.edu.

Publikováno v: Structure (London, England : 1993) [Structure] 2015 Oct 06; Vol. 23 (10), pp. 1910-1920. Date of Electronic Publication: 2015 Aug 27.

IL-1β Inhibition Partially Negates the Beneficial Effects of Diet-Induced Atherosclerosis Regression in Mice.

Autor: Karnewar, Santosh, Karnewar, Vaishnavi, Deaton, Rebecca A., Shankman, Laura S., Benavente, Ernest D., Williams, Corey M., Bradley, Xenia, Alencar, Gabriel F., Bulut, Gamze B., Kirmani, Sara, Baylis, Richard A., Zunder, Eli R., den Ruijter, Hester M., Pasterkamp, Gerard, Owens, Gary K.

Publikováno v: Arteriosclerosis, Thrombosis & Vascular Biology; Jun2024, Vol. 44 Issue 6, p1379-1392, 14p

TOLLIP acts as a cargo adaptor to promote lysosomal degradation of aberrant ER membrane proteins.

Autor: Hayashi, Yuki, Takatori, Sho, Warsame, Waleed Y, Tomita, Taisuke, Fujisawa, Takao, Ichijo, Hidenori

Publikováno v: EMBO Journal; Dec2023, Vol. 42 Issue 23, p1-20, 20p