Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Frazee James S"'
Autor:
Ohlstein, Eliot H., Nambi, Ponnal, Douglas, Stephen A., Edwards, Richard M., Gellai, Miklos, Lago, Amparo, Leer, Jack D., Cousins, Russell D., Gao, Aiming, Frazee, James S., Peishoff, Catherine E., Bean, John W., Eggleston, Drake S., Elshourbagy, Nabil A., Kumar, Chandrika, Lee, Jonathan A., Yue, Tian-Li, Louden, Calvert, Brooks, David P., Weinstock, Joseph, Feuerstein, Giora, Poste, George, Ruffolo,, Robert R., Gleason, John G., Elliott, John D.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1994 Aug . 91(17), 8052-8056.
Externí odkaz:
https://www.jstor.org/stable/2365628
Autor:
Stephen T. Ross, John L. Sawyer, L. I. Kruse, Frazee James S, Carl Kaiser, K. E. Flaim, Eileen L. Hilbert, Walter E. DeWolf, Joseph Alan Finkelstein
Publikováno v:
Journal of Medicinal Chemistry. 33:781-789
Structure-activity relationships (SAR) were determined for novel multisubstrate inhibitors of dopamine beta-hydroxylase (DBH; EC 1.14.17.1) by examining the effects upon in vitro inhibitory potencies resulting from structural changes at the copper-bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3b7ff12946d3ed525cb2fac6398c24
https://doi.org/10.1021/jm00164a051
https://doi.org/10.1021/jm00164a051
Autor:
Hammond, Marlys, Washburn, David G., Hoang, Tram H., Manns, Sharada, Frazee, James S., Nakamura, Hiroko, Patterson, Jaclyn R., Trizna, Walter, Wu, Charlene, Azzarano, Leonard M., Nagilla, Rakesh, Nord, Melanie, Trejo, Rebecca, Head, Martha S., Zhao, Baoguang, Smallwood, Angela M., Hightower, Kendra, Laping, Nicholas J., Schnackenberg, Christine G., Thompson, Scott K.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1 August 2009 19(15):4441-4445
Autor:
Washburn, David G., Hoang, Tram H., Frazee, James S., Johnson, Latisha, Hammond, Marlys, Manns, Sharada, Madauss, Kevin P., Williams, Shawn P., Duraiswami, Chaya, Tran, Thuy B., Stewart, Eugene L., Grygielko, Eugene T., Glace, Lindsay E., Trizna, Walter, Nagilla, Rakesh, Bray, Jeffrey D., Thompson, Scott K.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2009 19(16):4664-4668
Autor:
Thompson, Scott K., Washburn, David G., Frazee, James S., Madauss, Kevin P., Hoang, Tram H., Lapinski, Leahann, Grygielko, Eugene T., Glace, Lindsay E., Trizna, Walter, Williams, Shawn P., Duraiswami, Chaya, Bray, Jeffrey D., Laping, Nicholas J.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2009 19(16):4777-4780
Akademický článek
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Autor:
Bondinell, William E., Chapin, Frederic W., Frazee, James S., Girard, Gerald R., Holden, Kenneth G., Kaiser, Carl, Maryanoff, Cynthia, Perchonock, Carl D., Gessner, George W., Hieble, J. P., Hillegass, Leonard M., Pendleton, Robert G., Sawyer, John L.
Publikováno v:
Drug Metabolism Reviews; 1983, Vol. 14 Issue 4, p709-721, 13p
Autor:
K. E. Flaim, Walter E. DeWolf, Stephen T. Ross, Frazee James S, Wise M, Robert W. Erickson, L. I. Kruse, J. E. Wawro, Carl Kaiser, John L. Sawyer
Publikováno v:
Journal of Medicinal Chemistry. 30:486-494
1-Aralkylimidazole-2-thiones have been shown to be potent multisubstrate inhibitors of dopamine beta-hydroxylase (DBH; EC 1.14.17.1). In the present study, a series of 1-benzylimidazole-2-thiones was prepared to explore the effects of substitution in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47fbca15a0b8c1cae7ff0fd152c47718
https://doi.org/10.1021/jm00386a008
https://doi.org/10.1021/jm00386a008
Publikováno v:
Journal of Medicinal Chemistry. 20:1029-1035
Salbutamol, an adrenergic receptor agonist with selectivity for tracheobronchial vs. cardiac muscle, differs from the catecholamine N-tert-butylnorepinephrine in that it bears a hydroxymethyl, rather than a phenolic, group in the meta position. In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e401259a6061d3db1f3bf7c2600b49f
https://doi.org/10.1021/jm00218a008
https://doi.org/10.1021/jm00218a008
Autor:
Mark S. Schwartz, Karl F. Erhard, Joe R. Wardell, Carl Kaiser, Timothy Jen, Frazee James S, Donald F. Colella
Publikováno v:
Journal of Medicinal Chemistry. 20:1263-1268
Replacement of the benzylic hydroxyl group of N-tert-butylnorepinephrine with a hydroxymethyl substituent affords a propanolamine homologue which retains a high degree of beta-adrenergic agonist activity. As modification of the meta substituent of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f67acf2a425812bbeb3a85bd80b961ca
https://doi.org/10.1021/jm00220a007
https://doi.org/10.1021/jm00220a007