Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Frauke Liebelt"'
Autor:
Frauke Liebelt, Nicolette S. Jansen, Sumit Kumar, Ekaterina Gracheva, Laura A. Claessens, Matty Verlaan-de Vries, Edwin Willemstein, Alfred C. O. Vertegaal
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
While the biological roles of ubiquitin chains are well studied, little is known about the functions of SUMO polymers. Here, the authors identify poly-SUMOylation substrates and provide evidence that SUMO polymers regulate the accumulation of CCAN su
Externí odkaz:
https://doaj.org/article/8d573a3ede6f4566ad9972c15b4cb8c0
Autor:
Martin E. van Royen, Joost Schimmel, Esra Klemann, Frauke Liebelt, Yana van der Weegen, Leon H.F. Mullenders, Matty Verlaan-de Vries, Alex Pines, Wim Vermeulen, Alfred C.O. Vertegaal, Martijn S. Luijsterburg
Publikováno v:
Nucleic Acids Research, 48(1), 231-248. OXFORD UNIV PRESS
Nucleic Acids Research
Nucleic Acids Research, 48(1), 231-248. Oxford University Press
Nucleic Acids Research
Nucleic Acids Research, 48(1), 231-248. Oxford University Press
Cockayne Syndrome (CS) is a severe neurodegenerative and premature aging autosomal-recessive disease, caused by inherited defects in the CSA and CSB genes, leading to defects in transcription-coupled nucleotide excision repair (TC-NER) and consequent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ff3e5697a32c00975edfe2cfa7f1b5
https://hdl.handle.net/1887/3182621
https://hdl.handle.net/1887/3182621
Autor:
Monique P. C. Mulder, Remco Merkx, Katharina F. Witting, Dharjath S. Hameed, Dris El Atmioui, Lindsey Lelieveld, Frauke Liebelt, Jacques Neefjes, Ilana Berlin, Alfred C. O. Vertegaal, Huib Ovaa
Publikováno v:
Angewandte Chemie. 130:9096-9100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eb2a05709f7bdb250c79ed99dc99a5a
https://doi.org/10.1002/ange.201803483
https://doi.org/10.1002/ange.201803483
Autor:
Christopher L. Moore, Frauke Liebelt, Huib Ovaa, Monique P. C. Mulder, Matthew D. Shoulders, Alfred C.O. Vertegaal, Rebecca M. Sebastian
Publikováno v:
Cell Reports
Cell Reports, 26(1), 236
Elsevier
Cell Reports, 26(1), 236
Elsevier
Summary The role of stress-induced increases in SUMO2/3 conjugation during the heat shock response (HSR) has remained enigmatic. We investigated SUMO signal transduction at the proteomic and functional level during the HSR in cells depleted of proteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d9621d7986a01e336504e0176c0992
https://pubmed.ncbi.nlm.nih.gov/30605679
https://pubmed.ncbi.nlm.nih.gov/30605679
Autor:
Frauke Liebelt, Dris El Atmioui, Ilana Berlin, Huib Ovaa, Remco Merkx, Katharina F. Witting, Dharjath S. Hameed, Monique P. C. Mulder, Alfred C.O. Vertegaal, Lindsey T. Lelieveld, Jacques Neefjes
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie International Edition
Angewandte Chemie International Edition, 57(29), 8958-8962
Angewandte Chemie International Edition
Angewandte Chemie International Edition, 57(29), 8958-8962
SUMO is a post‐translational modifier critical for cell cycle progression and genome stability that plays a role in tumorigenesis, thus rendering SUMO‐specific enzymes potential pharmacological targets. However, the systematic generation of tools
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d7d8eb336e8c2fc4fe4810da3b2b5a
https://pubmed.ncbi.nlm.nih.gov/29771001
https://pubmed.ncbi.nlm.nih.gov/29771001
Autor:
Frauke Liebelt, David Baker, David G.P. van IJzendoorn, Judith V.M.G. Bovée, Aart G. Jochemsen, Alfred C.O. Vertegaal, Karoly Szuhai, Zary Forghany
Publikováno v:
Journal of Biological Chemistry, 292(52), 21282-21290
Epithelioid hemangioma is a locally aggressive vascular neoplasm, found in bones and soft tissue, whose cause is currently unknown, but may involve oncogene activation. FOS is one of the earliest viral oncogenes to be characterized, and normal cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb15bb1c734a584e6edfc31cd309cda
https://hdl.handle.net/1887/115797
https://hdl.handle.net/1887/115797
Autor:
Alfred C.O. Vertegaal, Frauke Liebelt
Publikováno v:
American Journal of Physiology-Cell Physiology, 311(2), C284-C296
American Journal of Physiology-Cell Physiology
American Journal of Physiology-Cell Physiology
Cellular proteomes are continuously undergoing alterations as a result of new production of proteins, protein folding, and degradation of proteins. The proper equilibrium of these processes is known as proteostasis, implying that proteomes are in hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a2e25f07f0a285e26d167e3732827b
https://hdl.handle.net/1887/111887
https://hdl.handle.net/1887/111887