Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Fraser T Sparks"'
Publikováno v:
PLoS Biology, Vol 16, Iss 1, p e2003354 (2018)
Behavior is used to assess memory and cognitive deficits in animals like Fmr1-null mice that model Fragile X Syndrome, but behavior is a proxy for unknown neural events that define cognitive variables like recollection. We identified an electrophysio
Externí odkaz:
https://doaj.org/article/8549272c141d4c8b94e7acd697d6941e
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27426 (2011)
Damage to the hippocampus (HPC) using the excitotoxin N-methyl-D-aspartate (NMDA) can cause retrograde amnesia for contextual fear memory. This amnesia is typically attributed to loss of cells in the HPC. However, NMDA is also known to cause intense
Externí odkaz:
https://doaj.org/article/dfbb90b015584d999a395a21462b3a45
Autor:
Carlos A. Lafourcade, Fraser T. Sparks, Angelique Bordey, Ursula Wyneken, Michael H. Mohammadi
Publikováno v:
Epilepsia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a5ec30f37156077b04f1cceeb39406b
https://doi.org/10.1111/epi.17569
https://doi.org/10.1111/epi.17569
Autor:
Jordan S. Farrell, Matthew Lovett-Barron, Peter M. Klein, Fraser T. Sparks, Tilo Gschwind, Anna L. Ortiz, Biafra Ahanonu, Susanna Bradbury, Satoshi Terada, Mikko Oijala, Ernie Hwaun, Barna Dudok, Gergely Szabo, Mark J. Schnitzer, Karl Deisseroth, Attila Losonczy, Ivan Soltesz
Publikováno v:
Science
Locomotion-related signals in the brain To calculate where we are in space, continuous knowledge of one’ s speed is necessary. How does the brain know how fast the body is traveling during locomotion? Using in vivo calcium imaging, electrophysiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1805ac90d18fe81ee9bb32507a0648
https://doi.org/10.1126/science.abh4272
https://doi.org/10.1126/science.abh4272
Publikováno v:
Nature Neuroscience. 24:1574-1585
Spatial memories that can last a lifetime are thought to be encoded during ‘online’ periods of exploration and subsequently consolidated into stable cognitive maps through their ‘offline’ reactivation. However, the mechanisms and computationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08c46093851df7496f1e2b7bd249818e
https://doi.org/10.1038/s41593-021-00920-7
https://doi.org/10.1038/s41593-021-00920-7
Autor:
Sebi V. Rolotti, Mohsin S. Ahmed, Miklos Szoboszlay, Tristan Geiller, Adrian Negrean, Heike Blockus, Kevin C. Gonzalez, Fraser T. Sparks, Ana Sofia Solis Canales, Anna L. Tuttman, Darcy S. Peterka, Boris V. Zemelman, Franck Polleux, Attila Losonczy
Publikováno v:
Neuron
Hippocampal place cells underlie spatial navigation and memory. Remarkably, CA1 pyramidal neurons can form new place fields within a single trial by undergoing rapid plasticity. However, local feedback circuits likely restrict the rapid recruitment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d056af2e4686a2834213939dc88712a
https://europepmc.org/articles/PMC8897257/
https://europepmc.org/articles/PMC8897257/
Autor:
Darcy S. Peterka, Franck Polleux, Heike Blockus, Kevin C. Gonzalez, Miklos Szoboszlay, Tristan Geiller, Ana Sofia Solis Canales, Sebi V. Rolotti, Fraser T. Sparks, Anna Tuttman, Attila Losonczy, Boris V. Zemelman, Adrian Negran, Mohsin Ahmed
Publikováno v:
SSRN Electronic Journal.
Hippocampal place cells form a physiological substrate for spatial navigation and memory in the brain. Remarkably, CA1 pyramidal neurons can acquire stable place fields in a few trials through a novel behavioral timescale" synaptic plasticity rule (B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39433d643e9ee6260fcd8fc672b66286
https://doi.org/10.2139/ssrn.3863581
https://doi.org/10.2139/ssrn.3863581
Autor:
Karl Deisseroth, Zhenrui Liao, Jure Leskovec, Scott C. Baraban, Darian Hadjiabadi, Fraser T. Sparks, Ivan Raikov, Ivan Soltesz, Matthew Lovett-Barron, Attila Losonczy
Neurological and psychiatric disorders are associated with pathological neural dynamics. The fundamental connectivity patterns of cell-cell communication networks that enable pathological dynamics to emerge remain unknown. We studied epileptic circui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::890e3778ada1c9c4943a1aa43c17fb7f
https://doi.org/10.1101/2020.10.20.340364
https://doi.org/10.1101/2020.10.20.340364
Autor:
Jordane Dimidschstein, Attila Losonczy, Olivia Fong, John C. Bowler, Hongkui Zeng, Brian Lee, Gergely G. Szabo, Ivan Soltesz, Jordan S. Farrell, Ernie Hwaun, Jim Berg, Bosiljka Tasic, Peter M. Klein, Zizhen Yao, Barna Dudok, Fraser T. Sparks, Tanya L. Daigle, Satoshi Terada, Gord Fishell
Publikováno v:
Neuron. 109(6)
Summary Interneurons expressing cholecystokinin (CCK) and parvalbumin (PV) constitute two key GABAergic controllers of hippocampal pyramidal cell output. Although the temporally precise and millisecond-scale inhibitory regulation of neuronal ensemble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ce58c7c478addfbc4c4538de126fd2
https://pubmed.ncbi.nlm.nih.gov/33735612
https://pubmed.ncbi.nlm.nih.gov/33735612
Publikováno v:
Nature neuroscience. 24(11)
Spatial memories that can last a lifetime are thought to be encoded during 'online' periods of exploration and subsequently consolidated into stable cognitive maps through their 'offline' reactivation. However, the mechanisms and computational princi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::204e36311ca1b9ded4dbf1edfcb13edc
https://pubmed.ncbi.nlm.nih.gov/34663956
https://pubmed.ncbi.nlm.nih.gov/34663956