Zobrazeno 1 - 10
of 3 304
pro vyhledávání: '"Fraser G"'
Autor:
R. Alan Aitken, Khadija Ait Moulay, David B. Cordes, Ryan A. Inwood, Fraser G. Jamieson, Alexander J. B. Nelson, Aidan P. McKay
Publikováno v:
Organics, Vol 5, Iss 1, Pp 12-31 (2024)
A series of fourteen O-ethyl-N-butylphenylphosphonamidates with benzyl ether substituents at the ortho position was prepared and fully characterised. Upon treatment with n-butyllithium in THF at RT, they underwent cyclisation in eight cases to give t
Externí odkaz:
https://doaj.org/article/7bb160c7549e4946872a87e08bc3ca0e
Autor:
Fraser G. Ferens, Cassandra C. Taber, Sarah Stuart, Mia Hubert, Daniel Tarade, Jeffrey E. Lee, Michael Ohh
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Pacak-Zhuang syndrome is caused by mutations in the EPAS1 gene, which encodes for one of the three hypoxia-inducible factor alpha (HIFα) paralogs HIF2α and is associated with defined but varied phenotypic presentations including neuroendoc
Externí odkaz:
https://doaj.org/article/ecd3feb7584042e8b24042291be7574e
Autor:
Benjamin P. MacLeod, Fraser G. L. Parlane, Connor C. Rupnow, Kevan E. Dettelbach, Michael S. Elliott, Thomas D. Morrissey, Ted H. Haley, Oleksii Proskurin, Michael B. Rooney, Nina Taherimakhsousi, David J. Dvorak, Hsi N. Chiu, Christopher E. B. Waizenegger, Karry Ocean, Mehrdad Mokhtari, Curtis P. Berlinguette
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Useful materials must satisfy multiple objectives. The Pareto front expresses the trade-offs of competing objectives. This work uses a self-driving laboratory to map out the Pareto front for making highly conductive coatings at low temperatures.
Externí odkaz:
https://doaj.org/article/8b6e898b1f8c4754af156c1427b0525f
Publikováno v:
eLife, Vol 11 (2022)
von Hippel-Lindau (VHL) disease is a rare hereditary cancer syndrome that causes a predisposition to renal clear-cell carcinoma, hemangioblastoma, pheochromocytoma, and autosomal-recessive familial polycythemia. pVHL is the substrate conferring subun
Externí odkaz:
https://doaj.org/article/f9f497551509475db5e06419e2dabacf
Autor:
Vladimir Shalgunov, Mengfei Xiong, Elina T. L’Estrade, Nakul R. Raval, Ida V. Andersen, Fraser G. Edgar, Nikolaj R. Speth, Simone L. Baerentzen, Hanne D. Hansen, Lene L. Donovan, Arafat Nasser, Siv T. Peitersen, Andreas Kjaer, Gitte M. Knudsen, Stina Syvänen, Mikael Palner, Matthias M. Herth
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Background Positron emission tomography (PET) is a molecular imaging technique that can be used to investigate the in vivo pharmacology of drugs. Initial preclinical evaluation of PET tracers is often conducted in rodents due to the accessib
Externí odkaz:
https://doaj.org/article/abd4cf9642dc46f89d08c15d1cabc529
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The voltage-dependent anion-selective channel (VDAC) is a porin in the mitochondrial outer membrane (MOM). Unlike bacterial porins, several mitochondrial β-barrels comprise an odd number of β-strands, as is the case for the 19-β-stranded VDAC. Pre
Externí odkaz:
https://doaj.org/article/487d3306d0aa43f3a9330dc4c8de2a82
Autor:
Elina Tampio L’Estrade, Fraser G. Edgar, Mengfei Xiong, Vladimir Shalgunov, Simone L. Baerentzen, Maria Erlandsson, Tomas G. Ohlsson, Mikael Palner, Gitte M. Knudsen, Matthias M. Herth
Publikováno v:
ACS Omega, Vol 4, Iss 4, Pp 7344-7353 (2019)
Externí odkaz:
https://doaj.org/article/a2f7493d2aa241d4aaf74d2a67c30505
Autor:
Fraser G. L. Parlane, Chantal Mustoe, Cameron W. Kellett, Sarah J. Simon, Wesley B. Swords, Gerald J. Meyer, Pierre Kennepohl, Curtis P. Berlinguette
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Dye-sensitized solar cells rely on molecular dyes to absorb light and conduct electrons. Parlane et al. show that weak forces such as hydrogen bonding can be responsible for the dye regeneration step of solar cells and have an impact on the photovolt
Externí odkaz:
https://doaj.org/article/2a520a95144848178164d54a2db93c10
Autor:
Simone Bærentzen, Agata Casado-Sainz, Denise Lange, Vladimir Shalgunov, Isabel Martinez Tejada, Mengfei Xiong, Elina T. L’Estrade, Fraser G. Edgar, Hedok Lee, Matthias M. Herth, Mikael Palner
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Chemogenetic studies with the ligand clozapine N-oxide (CNO) are predicated upon the assumption that CNO is devoid of actions at natural neuroreceptors. However, recent evidence shows that CNO may be converted back to clozapine (CLZ) in vivo, which c
Externí odkaz:
https://doaj.org/article/551a491d81c843848396af6bd5fc1577
