Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Franziska Wendt"'
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Akademický článek
A Thia-Analogous Indirubin N-Glycoside Disrupts Mitochondrial Function and Causes the Death of Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells
Autor: Franziska Wendt, Felix Wittig, Anne Rupprecht, Robert Ramer, Peter Langer, Steffen Emmert, Marcus Frank, Burkhard Hinz
Publikováno v: Cells, Vol 12, Iss 19, p 2409 (2023)
Skin cancer is the most common malignant disease worldwide and, therefore, also poses a challenge from a pharmacotherapeutic perspective. Derivatives of indirubin are an interesting option in this context. In the present study, the effects of 3-[3′
Externí odkaz: https://doaj.org/article/e4d653d7f8ce482784066c1f5d33ff3b
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2
Akademický článek
A Sensitive LC-MS/MS Method for the Simultaneous Determination of Two Thia-Analogous Indirubin N-Glycosides and Indirubin-3′-Monoxime in Plasma and Cell Culture Medium
Autor: Alica Fischle, Rico Schwarz, Franziska Wendt, Marcel Kordt, Robert Ramer, Lars Boeckmann, Martin Hein, Peter Langer, Steffen Emmert, Brigitte Vollmar, Burkhard Hinz
Publikováno v: Molecules, Vol 27, Iss 9, p 3031 (2022)
Indirubin was identified as an active component of Danggui Longhui Wan, an herbal mixture used in traditional Chinese medicine, and showed anticancer activity in clinical trials in patients with chronic leukemia. Investigations on the mechanisms of a
Externí odkaz: https://doaj.org/article/d38fd0ccc3254f87b1ae5939c608bd73
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4
The Combination of Δ9-Tetrahydrocannabinol and Cannabidiol Suppresses Mitochondrial Respiration of Human Glioblastoma Cells via Downregulation of Specific Respiratory Chain Proteins
Autor: Anne Rupprecht, Ulrike Theisen, Franziska Wendt, Marcus Frank, Burkhard Hinz
Publikováno v: Cancers; Volume 14; Issue 13; Pages: 3129
Phytocannabinoids represent a promising approach in glioblastoma therapy. Previous work has shown that a combined treatment of glioblastoma cells with submaximal effective concentrations of psychoactive Δ9-tetrahydrocannabinol (THC) and non-psychoac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3cf28b205e02c02aebe56bffcfad75
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6
Impact of Cannabinoid Compounds on Skin Cancer
Autor: Robert Ramer, Franziska Wendt, Felix Wittig, Mirijam Schäfer, Lars Boeckmann, Steffen Emmert, Burkhard Hinz
Publikováno v: Cancers. 14(7)
Drugs targeting the endocannabinoid system are of interest as potential systemic chemotherapeutic treatments and for palliative care in cancer. In this context, cannabinoid compounds have been successfully tested as a systemic therapeutic option in p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac9539b84fe29e4247c6b91da1c7f27
https://pubmed.ncbi.nlm.nih.gov/35406541
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7
Platelet Induced Functional Alteration of CD4
Autor: Christina, Polasky, Franziska, Wendt, Ralph, Pries, Barbara, Wollenberg
Publikováno v: International Journal of Molecular Sciences
Platelets (PLT) are the second most abundant cell type in human blood and exert various immune-regulatory functions under both physiological and pathological conditions. In fact, immune cell regulation via platelets has been demonstrated in several s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2ea37ee1052bb5b2f87d9a7092d8eef3
https://pubmed.ncbi.nlm.nih.gov/33053760
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8
Platelet Induced Functional Alteration of CD4+ and CD8+ T Cells in HNSCC
Autor: Christina Polasky, Ralph Pries, Franziska Wendt, Barbara Wollenberg
Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7507, p 7507 (2020)
Platelets (PLT) are the second most abundant cell type in human blood and exert various immune-regulatory functions under both physiological and pathological conditions. In fact, immune cell regulation via platelets has been demonstrated in several s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3c133273fd6ff5af1a1c937169e7cd
https://mediatum.ub.tum.de/doc/1689413/document.pdf
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9
Tyrosinase and catechol oxidase activity of copper(I) complexes supported by imidazole-based ligands: structure–reactivity correlations
Autor: Felix Tuczek, Franziska Wendt, Christian Näther
Publikováno v: JBIC Journal of Biological Inorganic Chemistry. 21:777-792
Four new imidazole-based ligands, 4-((1H-imidazol-4-yl)methyl)-2-phenyl-4,5-dihydrooxyzole (L OL 1), 4-((1H-imidazol-4-yl)methyl)-2-(tert-butyl)-4,5-dihydrooxyzole (L OL 2), 4-((1H-imidazol-4-yl)methyl)-2-methyl-4,5-dihydrooxyzole (L OL 3), and N-(2,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea4f6bf9d23e52f95ba1aeb0b26c520
https://doi.org/10.1007/s00775-016-1370-y
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10
Abstract 416: Are Good and Evil Polarized? - How Murine Rgs5 knock-out Influences Macrophage Polarization and Aortic Atherosclerosis and Dissection
Autor: Gregor Theilmeier, Nicolina Wibbe, Franziska Wendt, Houra Loghmani, Greta Ginski, Niandan Hu, Uwe Raaz, Isabel N Schellinger
Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Background: Aortic atherosclerosis and dissection cause significant morbidity and mortality. Although atherosclerosis is associated with aortic dissection, points of interaction are unclear. Regulator-of-G-protein signaling 5 (RGS5) is still insuffic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::970f2076ddf46c1575b7c8a018d7a9d6
https://doi.org/10.1161/atvb.38.suppl_1.416
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