Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Franziska Wedekind"'
Autor:
Xuan He, Franziska Wedekind, Tina Kroll, Angela Oskamp, Simone Beer, Alexander Drzezga, Johannes Ermert, Bernd Neumaier, Andreas Bauer, David Elmenhorst
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
PurposeIn vivo imaging for the A1 adenosine receptors (A1ARs) with positron emission tomography (PET) using 8-cyclopentyl-3-(3-[18F]fluoropropyl)-1-propylxan- thine ([18F]CPFPX) has become an important tool for studying physiological processes quanti
Externí odkaz:
https://doaj.org/article/b84e31c0ec174ee7b0f089c221d3c2d4
Autor:
Felix Neumaier, Annette Schulze, Birte Drewes, Wiebke Sihver, Dirk Bier, Franziska Wedekind, Marcus H. Holschbach, Bernd Neumaier, Andreas Bauer
Publikováno v:
Journal of radioanalytical and nuclear chemistry 326(3), 1691-1697 (2020). doi:10.1007/s10967-020-07465-2
5-Iodotubercidin is a prototype adenosine kinase (AK) inhibitor with potent anti-seizure activity in rodent epilepsy models. Using the chloramine-T method for radioiodination of tubercidin with 131I, we prepared no-carrier-added 5-[131I]iodotubercidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63bb9cabbd3e0e4c3c651b8ca5adde62
https://doi.org/10.1007/s10967-020-07465-2
https://doi.org/10.1007/s10967-020-07465-2
Autor:
Dirk Bier, Erika Wabbals, Marcus H. Holschbach, Franziska Wedekind, Marcel Skraban, Annette Schulze, Dana R. Renk, Felix Neumaier, Bernd Neumaier
Publikováno v:
European journal of medicinal chemistry 214, 113214 (2021). doi:10.1016/j.ejmech.2021.113214
With the aim to obtain potent adenosine A2A receptor (A2AR) ligands, a series of eighteen derivatives of 4-hydroxy-N-(4-methoxy-7-morpholin-4-yl-1,3-benzo[d]thiazol-2-yl)-4-methylpiperidine-1-carboxamide (SYN-115, Tozadenant) were designed and synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed80f9f375d549973d67523f161172ae
https://hdl.handle.net/2128/27464
https://hdl.handle.net/2128/27464
Autor:
Dana R, Renk, Marcel, Skraban, Dirk, Bier, Annette, Schulze, Erika, Wabbals, Franziska, Wedekind, Felix, Neumaier, Bernd, Neumaier, Marcus, Holschbach
Publikováno v:
European journal of medicinal chemistry. 214
With the aim to obtain potent adenosine A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::333692951d24ccd435acf6f58577a219
https://pubmed.ncbi.nlm.nih.gov/33548636
https://pubmed.ncbi.nlm.nih.gov/33548636
Autor:
Karl Zilles, Angela Oskamp, Alexander Hawlitschka, Andreas Bauer, Franziska Wedekind, Andreas Wree, Markus Lang
Publikováno v:
Journal of Neuroscience Research. 96:75-86
Cerebral administration of botulinum neurotoxin A (BoNT-A) has been shown to improve disease-specific motor behavior in a rat model of Parkinson disease (PD). Since the dopaminergic system of the basal ganglia fundamentally contributes to motor funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::879a7c114c4de762f0042a45667bacb2
https://doi.org/10.1002/jnr.24110
https://doi.org/10.1002/jnr.24110
Publikováno v:
Chronobiology International. 34:866-875
Wakefulness and sleep are fundamental characteristics of the brain. We, therefore, hypothesized that transmitter systems contribute to their regulation and will exhibit circadian alterations.We assessed the concentration of various neurotransmitter r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a930a5489163602e6d7290c5df6bec
https://doi.org/10.1080/07420528.2017.1325370
https://doi.org/10.1080/07420528.2017.1325370
Autor:
David Elmenhorst, Franziska Wedekind, Tina Kroll, Simone Beer, Heinz H. Coenen, Angela Oskamp, Johannes Ermert, Kristina Mertens, Eva-Maria Elmenhorst, Andreas Bauer
Publikováno v:
Journal of Sleep Research. 25:754-761
The metabotrophic subtype 5 glutamate receptor (mGluR5) plays a critical role in synaptic plasticity besides its involvement in numerous neurological disorders, such as depression. As mGluR5 availability in humans is altered in sleep deprivation, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063374171b405cfd9c606a684ca36e25
https://doi.org/10.1111/jsr.12432
https://doi.org/10.1111/jsr.12432
Autor:
Franziska, Wedekind, Angela, Oskamp, Markus, Lang, Alexander, Hawlitschka, Karl, Zilles, Andreas, Wree, Andreas, Bauer
Publikováno v:
Journal of neuroscience research. 96(5)
Cerebral administration of botulinum neurotoxin A (BoNT-A) has been shown to improve disease-specific motor behavior in a rat model of Parkinson disease (PD). Since the dopaminergic system of the basal ganglia fundamentally contributes to motor funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9f8ccbc5db8fce884a0079df53689291
https://pubmed.ncbi.nlm.nih.gov/28695985
https://pubmed.ncbi.nlm.nih.gov/28695985
Autor:
Angela Weisshaupt, Simone Beer, David Elmenhorst, Andreas Bauer, Andreas Matusch, Franziska Wedekind, Tina Kroll, Avdo Celik
Publikováno v:
Nuclear Medicine and Biology. 41:1-9
Introduction The selective 5-hydroxytryptamine type 2a receptor (5-HT 2A R) radiotracer [ 18 F]altanserin is a promising ligand for in vivo brain imaging in rodents. However, [ 18 F]altanserin is a substrate of P-glycoprotein (P-gp) in rats. Its appl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d10181729754bf2e5989f3afc8dec3e
https://doi.org/10.1016/j.nucmedbio.2013.09.001
https://doi.org/10.1016/j.nucmedbio.2013.09.001
Autor:
Tina Kroll, Andreas Matusch, Franziska Wedekind, Angela Weisshaupt, David Elmenhorst, Simone Beer, Andreas Bauer
Publikováno v:
Molecular Imaging and Biology. 15:456-467
While the selective 5-hydroxytryptamine type 2a receptor (5-HT2AR) radiotracer [18F]altanserin is well established in humans, the present study evaluated its suitability for quantifying cerebral 5-HT2ARs with positron emission tomography (PET) in alb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92b66b8c78859daac3fe09de3f1fd05
https://doi.org/10.1007/s11307-013-0621-3
https://doi.org/10.1007/s11307-013-0621-3