Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Franziska Wagen"'
Autor:
Mariana Borsa, Niculò Barandun, Fabienne Gräbnitz, Isabel Barnstorf, Nicolas S. Baumann, Katharina Pallmer, Samira Baumann, Dominique Stark, Miroslav Balaz, Nathalie Oetiker, Franziska Wagen, Christian Wolfrum, Anna Katharina Simon, Nicole Joller, Yves Barral, Roman Spörri, Annette Oxenius
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Asymmetrical cell division helps to maintain cellular heterogeneity in the T cell compartment. Here the authors examine the differential immune responses built by naive and virtual memory T cells from young and aged individuals, and explore the effec
Externí odkaz:
https://doaj.org/article/61aae8a737c543db8b183a3356289468
Autor:
Suzanne P. M. Welten, Alexander Yermanos, Nicolas S. Baumann, Franziska Wagen, Nathalie Oetiker, Ioana Sandu, Alessandro Pedrioli, Jennifer D. Oduro, Sai T. Reddy, Luka Cicin-Sain, Werner Held, Annette Oxenius
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Upon infection with cytomegalovirus, CD8+ T cells undergo prolific expansion in a process known as memory inflation. Here the authors define a population of Tcf1 expressing cells within the inflationary pool that is critical in fuelling this process.
Externí odkaz:
https://doaj.org/article/ba32f60be74545d6b1590448839902d6
Autor:
Ioana Sandu, Dario Cerletti, Nathalie Oetiker, Mariana Borsa, Franziska Wagen, Ilaria Spadafora, Suzanne P.M. Welten, Ugne Stolz, Annette Oxenius, Manfred Claassen
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108078- (2020)
Summary: A hallmark of chronic infections is the presence of exhausted CD8 T cells, characterized by a distinct transcriptional program compared with functional effector or memory cells, co-expression of multiple inhibitory receptors, and impaired ef
Externí odkaz:
https://doaj.org/article/d6da9e5548be4a6f82dcc718fcd85cb0
Autor:
Alexander Yermanos, Ioana Sandu, Alessandro Pedrioli, Mariana Borsa, Franziska Wagen, Nathalie Oetiker, Suzanne P. M. Welten, Katharina Pallmer, Sai T. Reddy, Annette Oxenius
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
CD8 T cells play a crucial role in providing protection from viral infections. It has recently been established that a subset of CD8 T cells expressing Tcf1 are responsible for sustaining exhausted T cells during chronic lymphocytic choriomeningitis
Externí odkaz:
https://doaj.org/article/1a477170752c4533a2dbb84ed90972bd
Autor:
Nathalie Oetiker, Ioana Sandu, Alessandro Pedrioli, Alexander Yermanos, Nicolas S. Baumann, Werner Held, Jennifer D. Oduro, Franziska Wagen, Sai T. Reddy, Annette Oxenius, Suzanne P. M. Welten, Luka Cicin-Sain
Publikováno v:
Nature communications
England
Nature Communications, 11 (1)
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, vol. 11, no. 1, pp. 2295
England
Nature Communications, 11 (1)
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, vol. 11, no. 1, pp. 2295
Cytomegalovirus-based vaccine vectors offer interesting opportunities for T cell-based vaccination purposes as CMV infection induces large numbers of functional effector-like cells that accumulate in peripheral tissues, a process termed memory inflat
Autor:
Nathalie Oetiker, Ioana Sandu, Katharina Pallmer, Alessandro Pedrioli, Annette Oxenius, Mariana Borsa, Suzanne P. M. Welten, Sai T. Reddy, Alexander Yermanos, Franziska Wagen
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, 11
Frontiers in Immunology, 11
CD8 T cells play a crucial role in providing protection from viral infections. It has recently been established that a subset of CD8 T cells expressing Tcf1 are responsible for sustaining exhausted T cells during chronic lymphocytic choriomeningitis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193df9cf4493bc85ca2050fcf0287fb9
Autor:
Suzanne P M, Welten, Alexander, Yermanos, Nicolas S, Baumann, Franziska, Wagen, Nathalie, Oetiker, Ioana, Sandu, Alessandro, Pedrioli, Jennifer D, Oduro, Sai T, Reddy, Luka, Cicin-Sain, Werner, Held, Annette, Oxenius
Publikováno v:
Nature Communications
Cytomegalovirus-based vaccine vectors offer interesting opportunities for T cell-based vaccination purposes as CMV infection induces large numbers of functional effector-like cells that accumulate in peripheral tissues, a process termed memory inflat
Autor:
Mariana Borsa, Nathalie Oetiker, Ilaria Spadafora, Dario Cerletti, Ugne Stolz, Annette Oxenius, Manfred Claassen, Suzanne P. M. Welten, Ioana Sandu, Franziska Wagen
Publikováno v:
Cell Reports, 32 (8)
Cell Reports, Vol 32, Iss 8, Pp 108078-(2020)
Cell Reports, Vol 32, Iss 8, Pp 108078-(2020)
A hallmark of chronic infections is the presence of exhausted CD8 T cells, characterized by a distinct transcriptional program compared with functional effector or memory cells, co-expression of multiple inhibitory receptors, and impaired effector fu
Autor:
Nicolas S. Baumann, Annette Oxenius, Franziska Wagen, Roman Spörri, Yves Barral, Anna Katharina Simon, Dominique Stark, Nathalie Oetiker, Mariana Borsa, Fabienne Gräbnitz, Miroslav Balaz, Katharina Pallmer, Isabel Barnstorf, Christian Wolfrum, Nicole Joller, Samira Baumann, Niculò Barandun
Publikováno v:
Nature Communications, 12 (1)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Efficient immune responses rely on heterogeneity, which in CD8+ T cells, amongst other mechanisms, is achieved by asymmetric cell division (ACD). Here we find that ageing, known to negatively impact immune responses, impairs ACD in murine CD8+ T cell