Výsledky vyhledávání - "Franziska Tuchen"

polymorphisms and the interindividual variability in pharmacokinetics and pharmacodynamics of the loop diuretic drug torsemide

Autor: Julia Kirchheiner, Sabine Engelhardt, Jürgen Brockmöller, Stefan Viktor Vormfelde, Franziska Tuchen, Alexandra Zirk, Ingolf Meineke

Publikováno v: Clinical Pharmacology & Therapeutics. 76:557-566

Introduction According to in vitro data, torsemide (INN, torasemide) is a substrate of the genetically polymorphic enzyme cytochrome P450 (CYP) 2C9, but the impact of CYP2C9 polymorphisms on torsemide pharmacokinetics and pharmacodynamics has not bee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6ddbba83143a73e6429f1aaab12bb6c
https://doi.org/10.1016/j.clpt.2004.08.024

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CYP2C9 polymorphisms and the interindividual variability in pharmacokinetics and pharmacodynamics of the loop diuretic drug torsemide

Autor: Stefan Viktor, Vormfelde, Sabine, Engelhardt, Alexandra, Zirk, Ingolf, Meineke, Franziska, Tuchen, Julia, Kirchheiner, Jürgen, Brockmöller

Publikováno v: Clinical pharmacology and therapeutics. 76(6)

According to in vitro data, torsemide (INN, torasemide) is a substrate of the genetically polymorphic enzyme cytochrome P450 (CYP) 2C9, but the impact of CYP2C9 polymorphisms on torsemide pharmacokinetics and pharmacodynamics has not been studied in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9ff98148e7baa40aa5b8a5b30ff13224
https://pubmed.ncbi.nlm.nih.gov/15592327

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