Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Franziska Trippel"'
Autor:
Alexander Beck, Franziska Trippel, Alexandra Wagner, Saskia Joppien, Max Felle, Christian Vokuhl, Thomas Schwarzmayr, Tim M. Strom, Dietrich von Schweinitz, Gernot Längst, Roland Kappler
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-11 (2018)
Abstract Background Hepatoblastoma (HB) is the most common liver tumor of childhood and occurs predominantly within the first 3 years of life. In accordance to its early manifestation, HB has been described to display an extremely low mutation rate.
Externí odkaz:
https://doaj.org/article/89947d49a2ce4ad886da6e6cd9c431ea
Autor:
Jochen Hubertus, Ferdinand Zitzmann, Franziska Trippel, Josef Müller-Höcker, Maximilian Stehr, Dietrich von Schweinitz, Roland Kappler
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67605 (2013)
Aberrant expression of imprinted genes, such as those coding for the insulin-like growth factor 2 (IGF2) and neuronatin (NNAT), is a characteristic of a variety of embryonic neoplasms, including Wilms tumor (WT). In case of IGF2, it is generally acce
Externí odkaz:
https://doaj.org/article/b7928e3bac9d41f698f9d46ad9729221
Autor:
Franziska Trippel, Dietrich von Schweinitz, Josef Müller-Höcker, Elke Luxenburger, Jan Gödeke, Kristina Becker, Beate Häberle, Roland Kappler
Publikováno v:
Hepatology International. 10:370-376
Despite tremendous progress in therapy, about 30 % of patients with hepatoblastoma still succumb to the disease. Thus, the development of improved therapies as well as the identification of prognostic factors are urgently needed. In the present study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56c258b852ccd6637cf419123dcec0f
https://doi.org/10.1007/s12072-015-9686-1
https://doi.org/10.1007/s12072-015-9686-1
Autor:
Roland Kappler, Stefano Cairo, Ivo Leuschner, Alexander M. Beck, Michaela Kreuder, Thomas Schwarzmayr, Tim M. Strom, Beate Häberle, Dietrich von Schweinitz, Melanie Eichenmüller, Franziska Trippel
Publikováno v:
Journal of Hepatology. 61:1312-1320
Background & Aims Hepatoblastoma (HB) is the most common childhood liver cancer and occasionally presents with histological and clinical features reminiscent of hepatocellular carcinoma (HCC). Identification of molecular mechanisms that drive the neo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc7153b083bfca99822043969792bd2f
https://doi.org/10.1016/j.jhep.2014.08.009
https://doi.org/10.1016/j.jhep.2014.08.009
Autor:
D. von Schweinitz, Melanie Eichenmüller, R Kappler, Tim M. Strom, I Leuschner, Franziska Trippel
Publikováno v:
Klinische Pädiatrie. 225
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0ebbf7eacc908768a3fc33b67958c3f
https://doi.org/10.1055/s-0033-1343659
https://doi.org/10.1055/s-0033-1343659
Autor:
Dietrich von Schweinitz, Maximilian Stehr, Jochen Hubertus, Franziska Trippel, Ferdinand Zitzmann, Josef Müller-Höcker, Roland Kappler
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67605 (2013)
PLoS ONE
PLoS ONE
Aberrant expression of imprinted genes, such as those coding for the insulin-like growth factor 2 (IGF2) and neuronatin (NNAT), is a characteristic of a variety of embryonic neoplasms, including Wilms tumor (WT). In case of IGF2, it is generally acce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287c99151a0842fe71329c576124e895
http://europepmc.org/articles/PMC3692448?pdf=render
http://europepmc.org/articles/PMC3692448?pdf=render
Publikováno v:
Klinische Pädiatrie. 224
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b72d156de55c925d496f7fa191de0d99
https://doi.org/10.1055/s-0032-1310493
https://doi.org/10.1055/s-0032-1310493
Publikováno v:
Klinische Pädiatrie. 224
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca592c10a25025bdda7787644b9ea969
https://doi.org/10.1055/s-0032-1310492
https://doi.org/10.1055/s-0032-1310492
Autor:
Melanie Eichenmüller, Tim M. Strom, Franziska Trippel, Roland Kappler, Dietrich von Schweinitz
Publikováno v:
Cancer Research. 74:3086-3086
Hepatoblastoma (HB) is the most common malignant liver tumor in children with a histology that resembles various stages of the developing liver. To explore the genetic origin of this cancer, we performed whole-exome sequencing of 8 tumors and matched
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a558c27605f69ac790ee7a894ae64d35
https://doi.org/10.1158/1538-7445.am2014-3086
https://doi.org/10.1158/1538-7445.am2014-3086
Publikováno v:
Cancer Research. 72:1051-1051
Embryonal tumors are thought to arise from immature tissue during intrauterine or early postnatal development and display apart from specific genetic changes in developmental signaling pathways a relatively normal genomic background. Instead, epigene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9edd71af89edced904da8a62c8c79b9
https://doi.org/10.1158/1538-7445.am2012-1051
https://doi.org/10.1158/1538-7445.am2012-1051