On the role of allergen-specific IgG subclasses for blocking human basophil activation

Autor: Simon Zinkhan, Franziska Thoms, Gilles Augusto, Monique Vogel, Martin F. Bachmann

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Successful treatment of IgE mediated allergies by allergen-specific immunotherapy (AIT) usually correlates with the induction of allergen-specific IgG4. However, it is not clear whether IgG4 prevents the allergic reaction more efficiently than other

Externí odkaz: https://doaj.org/article/ceb42be06c094ad8a7c5863db6c6ecad

Lagrangian Residence Time in the Bay of Gdańsk, Baltic Sea

Autor: Joachim W. Dippner, Ines Bartl, Evridiki Chrysagi, Peter Holtermann, Anke Kremp, Franziska Thoms, Maren Voss

Publikováno v: Frontiers in Marine Science, Vol 6 (2019)

The impact of synoptic scale and mesoscale variability on the Lagrangian residence time (LRT) of the surface water in the Bay of Gdańsk was investigated using the results from an eddy-resolving model. The computed LRT of 53–60 days was up to four

Externí odkaz: https://doaj.org/article/822703c13c6f403a8153a1b3e3dd25c6

RNA and Toll-Like Receptor 7 License the Generation of Superior Secondary Plasma Cells at Multiple Levels in a B Cell Intrinsic Fashion

Autor: Caroline C. Krueger, Franziska Thoms, Elsbeth Keller, Fabiana M. S. Leoratti, Monique Vogel, Martin F. Bachmann

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Secondary plasma cells (PCs) originate from memory B cells and produce increased levels of antibodies with higher affinity compared to PCs generated during primary responses. Here we demonstrate that virus-like particles (VLPs) only induce secondary

Externí odkaz: https://doaj.org/article/08b7a80e96024981ab7b8bc0fd5038e3

Immunization of Cats against Fel d 1 Results in Reduced Allergic Symptoms of Owners

Autor: Franziska Thoms, Stefanie Haas, Aline Erhart, Claudia S. Nett, Silvia Rüfenacht, Nicole Graf, Arnis Strods, Gauravraj Patil, Thonur Leenadevi, Michael C. Fontaine, Lindsey A. Toon, Gary T. Jennings, Gabriela Senti, Thomas M. Kündig, Martin F. Bachmann

Publikováno v: Viruses, Vol 12, Iss 3, p 288 (2020)

An innovative approach was tested to treat cat allergy in humans by vaccinating cats with Fel-CuMV (HypoCatTM), a vaccine against the major cat allergen Fel d 1 based on virus-like particles derived from cucumber mosaic virus (CuMV-VLPs). Upon vaccin

Externí odkaz: https://doaj.org/article/bb1e4fe0915445ec86463168b95f3fa3

The Influence of Sediment‐Derived Dissolved Organic Matter in the Vistula River Estuary/Gulf of Gdansk

Autor: Colin A. Stedmon, Franziska Thoms, Maren Voss, Heather E. Reader

Publikováno v: Reader, H E, Thoms, F, Voss, M & Stedmon, C A 2019, ' The influence of sediment-derived dissolved organic matter in the Vistula River Estuary/Gulf of Gdansk ', Journal of Geophysical Research: Biogeosciences, vol. 124, no. 1, pp. 115-126 . https://doi.org/10.1029/2018JG004658

Dissolved organic matter (DOM) concentrations in sediment porewaters are often orders of magnitude higher than in the overlying water column resulting in a diffusive flux of DOM from sediments. The intensity and fate of this DOM flux is poorly unders

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932785db5a3bd85ae30067c1ffe66787
https://doi.org/10.1029/2018jg004658