Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Franziska S. Schulze"'
Tissue Destruction in Bullous Pemphigoid Can Be Complement Independent and May Be Mitigated by C5aR2
Autor:
Christian M. Karsten, Tina Beckmann, Maike M. Holtsche, Jenny Tillmann, Sabrina Tofern, Franziska S. Schulze, Eva Nina Heppe, Ralf J. Ludwig, Detlef Zillikens, Inke R. König, Jörg Köhl, Enno Schmidt
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Bullous pemphigoid (BP), the most frequent autoimmune bullous disorder, is a paradigmatic autoantibody-mediated disease associated with autoantibodies against BP180 (type XVII collagen, Col17). Several animal models have been developed that reflect i
Externí odkaz:
https://doaj.org/article/0c806351174d4d089d3c488476bf032f
Autor:
Unni K. Samavedam, Nina Mitschker, Anika Kasprick, Katja Bieber, Enno Schmidt, Tamás Laskay, Andreas Recke, S. Goletz, Gestur Vidarsson, Franziska S. Schulze, Mikko Armbrust, Katharina Schulze Dieckhoff, Hendri H. Pas, Marcel F. Jonkman, Kathrin Kalies, Detlef Zillikens, Yask Gupta, Saleh M. Ibrahim, Ralf J. Ludwig
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Because of the morbidity and limited therapeutic options of autoimmune diseases, there is a high, and thus far, unmet medical need for development of novel treatments. Pemphigoid diseases, such as epidermolysis bullosa acquisita (EBA), are prototypic
Externí odkaz:
https://doaj.org/article/fddf636d1efa4d1ebdc1ee6b3519797a
Autor:
Katja Bieber, Shijie Sun, Mareike Witte, Anika Kasprick, Foteini Beltsiou, Martina Behnen, Tamás Laskay, Franziska S. Schulze, Elena Pipi, Niklas Reichhelm, René Pagel, Detlef Zillikens, Enno Schmidt, Tim Sparwasser, Kathrin Kalies, Ralf J. Ludwig
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Regulatory T cells (Tregs) are well known for their modulatory functions in adaptive immunity. Through regulation of T cell functions, Tregs have also been demonstrated to indirectly curb myeloid cell-driven inflammation. However, direct effects of T
Externí odkaz:
https://doaj.org/article/d50872d56e25469c8896cd88f14dda80
Autor:
Sadegh Mousavi, Dirk Rades, Lenche Chakievska, Adam Wutkowski, Katja Bieber, Kathrin Kalies, Yask Gupta, Matthias Krajewski, Saleh M. Ibrahim, Ralf Ludwig, Peter König, Paul Schilf, Christian D. Sadik, Franziska S. Schulze, Markus Dahlke, Detlef Zillikens, Enno Schmidt, Dominik Schwudke, Tanya Sezin
Publikováno v:
Journal of Investigative Dermatology. 137:1104-1113
Recruitment of neutrophils and eosinophils into the skin is a hallmark of pemphigoid diseases. The molecular cues regulating granulocyte recruitment into the skin and the individual contributions of neutrophils and eosinophils to pemphigoid diseases
Autor:
Unni Krishna S. R. L. Samavedam, Katja Bieber, Kathrin Kalies, Ralf Ludwig, Anika Kasprick, Foteini Beltsiou, Marcel F. Jonkman, Hendri H. Pas, Katharina Schulze Dieckhoff, Misa Hirose, Franziska S. Schulze, Detlef Zillikens, Jennifer E. Hundt, Enno Schmidt
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 918-926 (2016)
Molecular medicine, 22, 918-926. FEINSTEIN INST MED RES
Molecular medicine, 22, 918-926. FEINSTEIN INST MED RES
Epidermolysis bullosa acquisita (EBA) is a difficult-to-treat subepidermal autoimmune blistering skin disease (AIBD) with circulating and tissue-bound anti-type VII collagen antibodies. Different reports have indicated increased concentration of tumo
Autor:
Franziska S. Schulze, Akira Ishiko, Sabrina Tofern, Enno Schmidt, Eva Nina Heppe, Atsushi Shimizu, Jörg Köhl, Christian Sina, Detlef Zillikens, Stephanie Goletz
Publikováno v:
The Journal of investigative dermatology. 137(8)
Mucous membrane pemphigoid is an autoantibody-mediated disease predominantly affecting the oral cavity, pharynx, and conjunctiva. Conjunctival lesions may lead to impaired vision and, finally, blindness. About 25% of mucous membrane pemphigoid patien
Autor:
Unni Krishna S. R. L. Samavedam, Franziska S. Schulze, Enno Schmidt, Hiroaki Iwata, Ralf Ludwig, Susen Müller, Andreas Recke, Detlef Zillikens
Publikováno v:
The Journal of Immunology. 192:559-571
GM-CSF activates hematopoietic cells and recruits neutrophils and macrophages to sites of inflammation. Inhibition of GM-CSF attenuates disease activity in models of chronic inflammatory disease. Effects of GM-CSF blockade were linked to modulation o
Autor:
Franziska Huebner, Detlef Zillikens, Andreas Recke, Enno Schmidt, Ingolf Karl, Nina van Beek, Franziska S. Schulze, Nadine Lüttmann
Publikováno v:
JAMA dermatology. 153(1)
Importance Bullous pemphigoid (BP) is by far the most frequent autoimmune blistering disease. The presence of IgE autoantibodies against the transmembrane protein BP antigen 2 (BP180, type XVII collagen) has previously been reported in 22% to 100% of
Publikováno v:
Der Hautarzt. 64:931-945
Pemphigoiderkrankungen sind eine Gruppe von Autoimmunerkrankungen, die charakterisiert sind durch eine subepidermale Blasenbildung sowie Autoantikorper gegen Strukturproteine der dermoepidermalen Junktionszone. Beim bullosen Pemphigoid, der haufigste
Autor:
Andreas Recke, Kathrin Neumann, Roland Linder, Enno Schmidt, Detlef Zillikens, Franziska S. Schulze
Publikováno v:
Journal of Investigative Dermatology. 135:1445-1447