Výsledky vyhledávání - "Franziska Rothemund"

Akademický článek

Cytomegalovirus immediate-early 1 proteins form a structurally distinct protein class with adaptations determining cross-species barriers.

Autor: Johannes Schweininger, Myriam Scherer, Franziska Rothemund, Eva-Maria Schilling, Sonja Wörz, Thomas Stamminger, Yves A Muller

Publikováno v: PLoS Pathogens, Vol 17, Iss 8, p e1009863 (2021)

Restriction factors are potent antiviral proteins that constitute a first line of intracellular defense by blocking viral replication and spread. During co-evolution, however, viruses have developed antagonistic proteins to modulate or degrade the re

Externí odkaz: https://doaj.org/article/77fb03220dbd48e8b450e0768989907b

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Akademický článek

Cross-Species Analysis of Innate Immune Antagonism by Cytomegalovirus IE1 Protein

Autor: Franziska Rothemund, Myriam Scherer, Eva-Maria Schilling, Johannes Schweininger, Yves A. Muller, Thomas Stamminger

Publikováno v: Viruses, Vol 14, Iss 8, p 1626 (2022)

The human cytomegalovirus (CMV) immediate early 1 (IE1) protein has evolved as a multifunctional antagonist of intrinsic and innate immune mechanisms. In addition, this protein serves as a transactivator and potential genome maintenance protein. Rece

Externí odkaz: https://doaj.org/article/75a7d6da698d4eafac098922a2e86aab

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Akademický článek

Functional regulation of the structure-specific endonuclease FEN1 by the human cytomegalovirus protein IE1 suggests a role for the re-initiation of stalled viral replication forks.

Autor: Eva-Maria Schilling, Myriam Scherer, Franziska Rothemund, Thomas Stamminger

Publikováno v: PLoS Pathogens, Vol 17, Iss 3, p e1009460 (2021)

Flap endonuclease 1 (FEN1) is a member of the family of structure-specific endonucleases implicated in regulation of DNA damage response and DNA replication. So far, knowledge on the role of FEN1 during viral infections is limited. Previous publicati

Externí odkaz: https://doaj.org/article/434dbcc0b9ee4202889748248af89427

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Cytomegalovirus immediate-early 1 proteins form a structurally distinct protein class with adaptations determining cross-species barriers

Autor: Thomas Stamminger, Sonja Wörz, Yves A. Muller, Franziska Rothemund, Johannes Schweininger, Myriam Scherer, Eva-Maria Schilling

Publikováno v: PLoS pathogens 17(8), e1009863-(2021). doi:10.1371/journal.ppat.1009863
PLoS Pathogens, Vol 17, Iss 8, p e1009863 (2021)
PLoS Pathogens

PLoS pathogens 17(8), e1009863 - (2021). doi:10.1371/journal.ppat.1009863
Restriction factors are potent antiviral proteins that constitute a first line of intracellular defense by blocking viral replication and spread. During co-evolution, howe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a040f3c5efc2e03c663ef9fb00db8438

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The N Terminus of Human Cytomegalovirus Glycoprotein O Is Important for Binding to the Cellular Receptor PDGFRα

Autor: Cora Stegmann, Barbara Adler, Kerstin Laib Sampaio, Christian Sinzger, Franziska Rothemund

Publikováno v: Journal of virology. 93(11)

The human cytomegalovirus (HCMV) glycoprotein complex gH/gL/gO is required for the infection of cells by cell-free virions. It was recently shown that entry into fibroblasts depends on the interaction of gO with the platelet-derived growth factor rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca94db464fc09b378a6326760f076d3e
https://pubmed.ncbi.nlm.nih.gov/30894468

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