Výsledky vyhledávání - "Franziska Reeder"

Determination by Electrospray Mass Spectrometry of the Outersphere Association Constants of DNA/Platinum Complexes Using 20-mer Oligonucleotides and ([Pt(NH3)4]2+, 2Cl−) or ([Pt(py)4]2+, 2Cl−)

Autor: Nathalie Carte, Noelle Potier, Alain Van Dorsselaer, Franziska Reeder, Franck Legendre, Jean-Claude Chottard, Emmanuelle Leize

Publikováno v: Analytical Biochemistry
Analytical Biochemistry, Elsevier Masson, 2000, 284 (1), pp.77-86. ⟨10.1006/abio.2000.4661⟩

The cytotoxic effects of cisplatin, cis -diamminedichloroplatinum(II), are generally ascribed to the formation of DNA adducts. Several in vitro as well as in vivo studies showed that cisplatin binds preferentially to guanines belonging to (G) n seque

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd70ad87d19141b0986a8c030be77e8
https://doi.org/10.1006/abio.2000.4661

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Kinetic aspects of interactions between DNA and platinum complexes

Autor: Jean-Claude Chottard, Franziska Reeder, Jiří Kozelka, Franck Legendre

Publikováno v: Coordination Chemistry Reviews. :61-82

Kinetic studies on reactions between oligonucleotides and platinum complexes related to the antitumor drug cisplatin are described. These studies were motivated by the sequence-selectivity observed for the reaction between cisplatin and DNA. Comparis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0674e580f90080900f7c18368ae7b400
https://doi.org/10.1016/s0010-8545(99)00065-x

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Kinetic Analysis of the Reactions between GG-Containing Oligonucleotides and Platinum Complexes. 1. Reactions of Single-Stranded Oligonucleotides with cis-[Pt(NH3)2(H2O)2]2+ and [Pt(NH3)3(H2O)]2+

Autor: Jiri Kozelka, Florence Gonnet, Franziska Reeder, Jean-Claude Chottard

Publikováno v: Inorganic Chemistry. 35:1653-1658

Using concentration measurements based on high performance liquid chromatography, we have investigated the kinetics of reaction between single-stranded oligonucleotides containing a d(GpG) sequence, i.e., d(GG), d(TGG), d(TTGG), and d(CTGGCTCA), and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a13583967aa12e089e0540fd5a6bca11
https://doi.org/10.1021/ic951136e

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Platination of a GG site on single-stranded and double-stranded forms of a 14-base oligonucleotide with diaqua cisplatin followed by NMR and HPLC -- influence of the platinum ligands and base sequence on 5'-G versus 3'-G platination selectivity

Autor: Alessandra Corazza, Jean-Claude Chottard, Zijian Guo, Piedad del Socorro Murdoch, Franziska Reeder, Trevor W. Hambley, Peter J. Sadler, Susan J. Berners-Price

Publikováno v: European journal of biochemistry. 249(2)

Detailed studies of the kinetics of platination of the single-stranded 14-base DNA oligonucleotide d(ATACATGGTACATA) and the corresponding duplex by cis-[Pt(NH3)2(H2O)2]2+ show that HPLC and NMR are complementary methods which provide similar results

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2054cbd23aee3eb4a33cbb979992f8d
https://pubmed.ncbi.nlm.nih.gov/9370343

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Kinetic Analysis of the Reactions between GG-Containing Oligonucleotides and Platinum Complexes. 1. Reactions of Single-Stranded Oligonucleotides with cis-[Pt(NH(3))(2)(H(2)O)(2)](2+) and [Pt(NH(3))(3)(H(2)O)](2+)

Autor: Florence, Gonnet, Franziska, Reeder, Jirí, Kozelka, Jean-Claude, Chottard

Publikováno v: Inorganic chemistry. 35(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a96e69f8b87e9e6fff9723c1058b62bc
https://pubmed.ncbi.nlm.nih.gov/11666387

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Triammineplatinum(II) Coordinated to a Guanine Does Not Prevent Platination of an Adjacent Guanine in Single-Stranded Oligonucleotides

Autor: Jean-Claude Chottard, Jiri Kozelka, Franziska Reeder

Publikováno v: Inorganic chemistry. 35(5)

Adjacent guanines within single-stranded oligodeoxyribonucleotides are shown to bind easily two dicationic platinum centers. This type of cumulative binding, which is favored by high ionic strength, should be taken into account in kinetic studies of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9649bbcdf72ab1b9281ca03bb13e116a
https://pubmed.ncbi.nlm.nih.gov/11666347

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Kinetic analysis of the two-step platination of oligonucleotides containing a GG-sequence

Autor: Jiri Kozelka, Franziska Reeder, Florence Gonnet, Jean-Claude Chottard

Publikováno v: Journal of Inorganic Biochemistry
7th Int. Symp. on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy
7th Int. Symp. on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, 1995, Amsterdam, Netherlands. pp.Abs 038
1995, Elsevier, pp.155, 1995
7th Int. Symp. on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, 1995, Amsterdam, Netherlands. pp.Abs 038, 1995

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15d0e60ca6a9babd7d88d8f1450254e
https://hal.archives-ouvertes.fr/hal-00068052

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