Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Franziska Petermann"'
Autor:
Sarah S. Geiger, Javier Traba, Nathan Richoz, Taylor K. Farley, Stephen R. Brooks, Franziska Petermann, Lingdi Wang, Frank J. Gonzalez, Michael N. Sack, Richard M. Siegel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Time of day influences immune responses and lethality in response to LPS, with survival greatest at the beginning compared to the end of the light cycle. Here the authors show that feeding, rather than light, controls time-of-day dependent LPS sensit
Externí odkaz:
https://doaj.org/article/c006a892d73b44e6afaa5d1292253d77
Autor:
Andreas Gewies, Oliver Gorka, Hanna Bergmann, Konstanze Pechloff, Franziska Petermann, Katharina M. Jeltsch, Martina Rudelius, Mark Kriegsmann, Wilko Weichert, Marion Horsch, Johannes Beckers, Wolfgang Wurst, Mathias Heikenwalder, Thomas Korn, Vigo Heissmeyer, Jürgen Ruland
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1292-1305 (2014)
The paracaspase Malt1 is a central regulator of antigen receptor signaling that is frequently mutated in human lymphoma. As a scaffold, it assembles protein complexes for NF-κB activation, and its proteolytic domain cleaves negative NF-κB regulator
Externí odkaz:
https://doaj.org/article/12cfc686bc3843e8bcaf50027277af30
Autor:
Hans Jürgen Solinski, Franziska Petermann, Kathrin Rothe, Ingrid Boekhoff, Thomas Gudermann, Andreas Breit
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58756 (2013)
Primate-specific Mas-related G protein-coupled receptors-X1 (MRGPR-X1) are highly enriched in dorsal root ganglia (DRG) neurons and induce acute pain. Herein, we analyzed effects of MRGPR-X1 on serum response factors (SRF) or nuclear factors of activ
Externí odkaz:
https://doaj.org/article/9c14ef663beb4416a56d4061dea2e544
Autor:
Jan D Haas, Kiran Nistala, Franziska Petermann, Namita Saran, Vijaykumar Chennupati, Susanne Schmitz, Thomas Korn, Lucy R Wedderburn, Reinhold Förster, Andreas Krueger, Immo Prinz
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20171 (2011)
Differentiation of T helper 17 cells (Th17) is a multistep process that involves the cytokines IL-6, TGF-β, and IL-23 as well as IL-1β, IL-21, and TNF-α. Thereby, robust induction of the capacity to produce IL-17 involves epigenetic modifications
Externí odkaz:
https://doaj.org/article/bed165c268e341f991d0911b65c3c69d
Autor:
Sudhakar Reddy Kalluri, Veit Rothhammer, Ori Staszewski, Rajneesh Srivastava, Franziska Petermann, Marco Prinz, Bernhard Hemmer, Thomas Korn
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16083 (2011)
BACKGROUND: Antibodies to the water channel protein aquaporin-4 (AQP4), which is expressed in astrocytic endfeet at the blood brain barrier, have been identified in the serum of Neuromyelitis optica (NMO) patients and are believed to induce damage to
Externí odkaz:
https://doaj.org/article/75d44cdd214449da85b981426629398d
Autor:
Hiroyuki Nagashima, Franziska Petermann, Aleksandra Pękowska, Vijender Chaitankar, Yuka Kanno, John J. O’Shea
The type 2 cytokines, interleukin (IL)-4, IL-5 and IL-13 reside within a tandem multi-gene cluster in mammals. These cytokines represent the hallmark of type 2 immune responses controlling parasites, promoting tissue repair as well as causing allergi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af8e7edf66da6a4c0e748885de15b9b5
https://doi.org/10.1101/2022.07.22.501024
https://doi.org/10.1101/2022.07.22.501024
Autor:
Michael N. Sack, Stephen R. Brooks, Taylor K. Farley, Richard M. Siegel, Lingdi Wang, Nathan Richoz, Javier Traba, Sarah S. Geiger, Frank J. Gonzalez, Franziska Petermann
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
In mice, time of day strongly influences lethality in response to LPS, with survival greatest at the beginning compared to the end of the light cycle. Here we show that feeding, rather than light, controls time-of-day dependent LPS sensitivity. Morta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464a7b3e06fa6cd2f7dd81aab2c7db58
https://doi.org/10.1038/s41467-021-22961-z
https://doi.org/10.1038/s41467-021-22961-z
Autor:
Stephen R. Brooks, Stefan A. Muljo, Hong-Wei Sun, John J. O'Shea, Yuka Kanno, Yohei Mikami, Amanda C. Poholek, Behdad Afzali, Hiroyuki Nagashima, Rachael L. Philips, Franziska Petermann, Fred P. Davis, Françoise Meylan, Giuseppe Sciumè, Markus Hafner, Han-Yu Shih, Hayato Takahashi, Chen Yao
Publikováno v:
Immunity
Summary MicroRNAs are important regulators of immune responses. Here, we show miR-221 and miR-222 modulate the intestinal Th17 cell response. Expression of miR-221 and miR-222 was induced by proinflammatory cytokines and repressed by the cytokine TGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bef81cb02bc1620f1db14a1bf4369c6
https://doi.org/10.1016/j.immuni.2021.02.015
https://doi.org/10.1016/j.immuni.2021.02.015
Autor:
Dragana Jankovic, Chen Yao, Alan Sher, Franziska Petermann, Catrina A. Johnson, Aleksandra Pekowska, William H. Hudson, Hong-Wei Sun, Yuka Kanno, Han-Yu Shih, Stephen R. Brooks, Kentner Singleton, Alejandro V. Villarino, Kan Jiang, Rama Akondy, John J. O'Shea, Rafael Casellas, Rafi Ahmed
Publikováno v:
Mol Cell
Summary Interferon gamma (IFN-γ), critical for host defense and tumor surveillance, requires tight control of its expression. Multiple cis-regulatory elements exist around Ifng along with a non-coding transcript, Ifng-as1 (also termed NeST). Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b68cf0533becfe11b2ffc65afb7afcc
https://pubmed.ncbi.nlm.nih.gov/31377117
https://pubmed.ncbi.nlm.nih.gov/31377117
Autor:
Amanda C, Poholek, Dragana, Jankovic, Alejandro V, Villarino, Franziska, Petermann, Angela, Hettinga, Dror S, Shouval, Scott B, Snapper, Susan M, Kaech, Stephen R, Brooks, Golnaz, Vahedi, Alan, Sher, Yuka, Kanno, John J, O'Shea
Publikováno v:
Science immunology. 1(5)
Blimp-1 expression in T cells extinguishes the fate of T follicular helper cells, drives terminal differentiation, and limits autoimmunity. Although various factors have been described to control Blimp-1 expression in T cells, little is known about w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bdd71f70520f7400f662cb35adbc1d28
https://pubmed.ncbi.nlm.nih.gov/28713870
https://pubmed.ncbi.nlm.nih.gov/28713870