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Autor:
Manuel Gregoritza, Maximilian Philipp, Ursula Storch, Michael Mederos y Schnitzler, Serap Erdogmus, Thomas Gudermann, Franziska Pardatscher, Anna-Lena Forst
Publikováno v:
Proc. Natl. Acad. Sci. U.S.A. 114, E37-E46 (2017)
The activation mechanism of the classical transient receptor potential channels TRPC4 and -5 via the G(q/11) protein-phospholipase C (PLC) signaling pathway has remained elusive so far. In contrast to all other TRPC channels, the PLC product diacylgl