Výsledky vyhledávání - "Franziska M. Feller"

Akademický článek

Substrate Inhibition of 5β-Δ4-3-Ketosteroid Dehydrogenase in Sphingobium sp. Strain Chol11 Acts as Circuit Breaker During Growth With Toxic Bile Salts

Autor: Franziska M. Feller, Gina Marke, Steffen L. Drees, Lars Wöhlbrand, Ralf Rabus, Bodo Philipp

Publikováno v: Frontiers in Microbiology, Vol 12 (2021)

In contrast to many steroid hormones and cholesterol, mammalian bile salts are 5β-steroids, which leads to a bent structure of the steroid core. Bile salts are surface-active steroids excreted into the environment in large amounts, where they are su

Externí odkaz: https://doaj.org/article/7abfcc29b82448a5b54165455b229d40

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Proteome, Bioinformatic, and Functional Analyses Reveal a Distinct and Conserved Metabolic Pathway for Bile Salt Degradation in the

Autor: Franziska M, Feller, Lars, Wöhlbrand, Johannes, Holert, Vanessa, Schnaars, Lea, Elsner, William W, Mohn, Ralf, Rabus, Bodo, Philipp

Publikováno v: Appl Environ Microbiol

Bile salts are amphiphilic steroids with digestive functions in vertebrates. Upon excretion, bile salts are degraded by environmental bacteria. Degradation of the bile salt steroid skeleton resembles the well-studied pathway for other steroids, like

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::55c0e650c3bb39b05ab3064cdac920a9
https://pubmed.ncbi.nlm.nih.gov/34260303

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