Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Franziska Lampart"'
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179995 (2017)
Currently most liver fibrosis research is performed in vivo, since suitable alternative in vitro systems which are able to recapitulate the cellular events leading to liver fibrosis are lacking. Here we aimed at generating a system containing cells r
Externí odkaz:
https://doaj.org/article/e749945b756e441dbf456b3056909393
Autor:
Franziska Lampart, Konrad Basler, Antonio Lentini, Mark D. Robinson, Nikolaos Doumpas, Colm E. Nestor, Claudio Cantù
Publikováno v:
The EMBO journal. 38(2)
During canonical Wnt signalling, the activity of nuclear β‐catenin is largely mediated by the TCF/LEF family of transcription factors. To challenge this view, we used the CRISPR/Cas9 genome editing approach to generate HEK 293T cell clones lacking
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 6, p e0179995 (2017)
PLoS ONE, Vol 12, Iss 6, p e0179995 (2017)
Background & aims Currently most liver fibrosis research is performed in vivo, since suitable alternative in vitro systems which are able to recapitulate the cellular events leading to liver fibrosis are lacking. Here we aimed at generating a system