Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Franziska Lademann"'
Autor:
Franziska Lademann, Eddy Rijntjes, Josef Köhrle, Elena Tsourdi, Lorenz C. Hofbauer, Martina Rauner
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Hyperthyroidism is a well-known trigger of high bone turnover that can lead to the development of secondary osteoporosis. Previously, we have shown that blocking bone morphogenetic protein (BMP) signaling systemically with BMPR1A-Fc can prev
Externí odkaz:
https://doaj.org/article/8b89a9a3c6184875be917878699170d0
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 8 (2023)
Osteocytes are specialized bone cells that orchestrate skeletal remodeling. Senescent osteocytes are characterized by an activation of cyclin-dependent kinase inhibitor p16Ink4a and have been implicated in the pathogenesis of several bone loss disord
Externí odkaz:
https://doaj.org/article/9530309893c8457f8ee6bedfc723193d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Bone health crucially relies on constant bone remodeling and bone regeneration, both tightly controlled processes requiring bone formation and bone resorption. Plenty of evidence identifies bone morphogenetic proteins (BMP) as major players in osteob
Externí odkaz:
https://doaj.org/article/f584b8d85b5d4d86a883d636615a7fa0
Autor:
Elisabeth Jahny, Hai Yang, Bin Liu, Beatrix Jahnke, Franziska Lademann, Thomas Knösel, Petra Rümmele, Robert Grützmann, Daniela E Aust, Christian Pilarsky, Axel Denz
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170390 (2017)
Pancreatic Ductal Adenocarcinoma (PDAC) is one of the deadliest tumors worldwide. Understanding the function of gene expression alterations is a prerequisite for developing new strategies in diagnostic and therapy. GPRC5A (RAI3), coding for a seven t
Externí odkaz:
https://doaj.org/article/2a38954f87e44e79aa01c41780858705
Publikováno v:
Osteologie. 31:262-269
ZusammenfassungDie Schilddrüsenhormone L-Thyroxin und 3,3',5-Triiod-L-thyronin spielen eine zentrale Rolle im Skelettwachstum und beim Erhalt eines gesunden Knochens im Erwachsenenalter. Auf zellulärer Ebene sind die Wirkungen von Schilddrüsenhorm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04e211686998a3aac43aa480ba1c6258
https://doi.org/10.1055/a-1951-1233
https://doi.org/10.1055/a-1951-1233
Autor:
null Eva M. Wölfel, null Franziska Lademann, null Haniyeh Hemmatian, null Stéphane Blouin, null Phaedra Messmer, null Lorenz C. Hofbauer, null Björn Busse, null Martina Rauner, null Katharina Jähn‐Rickert, null Elena Tsourdi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50779ffba9d06d76f028272042ed5be
https://doi.org/10.1002/jbmr.4736/v3/response1
https://doi.org/10.1002/jbmr.4736/v3/response1
Autor:
Eva Maria Wölfel, Franziska Lademann, Haniyeh Hemmatian, Stéphane Blouin, Phaedra Messmer, Lorenz C. Hofbauer, Björn Busse, Martina Rauner, Katharina Jähn‐Rickert, Elena Tsourdi
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchReferences. 38(1)
Hyperthyroidism causes secondary osteoporosis through favoring bone resorption over bone formation, leading to bone loss with elevated bone fragility. Osteocytes that reside within lacunae inside the mineralized bone matrix orchestrate the process of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360ea3d01109ddf052db05b38a58142f
https://pubmed.ncbi.nlm.nih.gov/36331133
https://pubmed.ncbi.nlm.nih.gov/36331133
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 9; Pages: 1462
Bone is a large and dynamic tissue and its maintenance requires high amounts of energy as old or damaged bone structures need to be replaced during the process of bone remodeling. Glucose homeostasis is an essential prerequisite for a healthy bone an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3352be0cfb23acd6f0f5e2bf5340dec
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 128:450-454
Thyroid hormones are indispensable for bone development and growth. Also in adults, bone mass maintenance is under the control of thyroid hormones. Preclinical and clinical studies established untreated hyperthyroidism as a cause for secondary osteop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff6de8c4080699de24312d98b6c4222
https://doi.org/10.1055/a-1088-1215
https://doi.org/10.1055/a-1088-1215
Autor:
Elena Tsourdi, Athanasios D. Anastasilakis, Lorenz C. Hofbauer, Martina Rauner, Franziska Lademann
Publikováno v:
Journal of Clinical Medicine. 11:6863
Irisin is a hormone-like myokine produced by the skeletal muscle in response to exercise. Upon its release into the circulation, it is involved in the browning process and thermogenesis, but recent evidence indicates that this myokine could also regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b969f8f586e76b35d81719abcd72b949
https://doi.org/10.3390/jcm11226863
https://doi.org/10.3390/jcm11226863