Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Franziska Kriegenburg"'
Autor:
Franziska Kriegenburg, Wouter Huiting, Fleur van Buuren-Broek, Emma Zwilling, Ralph Hardenberg, Muriel Mari, Claudine Kraft, Fulvio Reggiori
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 345-367 (2022)
Macroautophagy/autophagy is a conserved catabolic pathway during which cellular material is sequestered within newly formed double-membrane vesicles called autophagosomes and delivered to the lytic compartment of eukaryotic cells for degradation. Aut
Externí odkaz:
https://doaj.org/article/b2c1b2bfca1e4d258a67a3f45a7b2b7d
Autor:
Jana Sánchez-Wandelmer, Franziska Kriegenburg, Sabrina Rohringer, Martina Schuschnig, Rubén Gómez-Sánchez, Bettina Zens, Susana Abreu, Ralph Hardenberg, David Hollenstein, Jieqiong Gao, Christian Ungermann, Sascha Martens, Claudine Kraft, Fulvio Reggiori
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
The protease Atg4 mediates Atg8 lipidation, required for autophagosome biogenesis, but also triggers Atg8 release from the membranes, however is unclear how these steps are coordinated. Here the authors show that phosphorylation by Atg1 inhibits Atg4
Externí odkaz:
https://doaj.org/article/0d25d8e1163b4f90ae02c9c439b13fba
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Coronaviruses (CoV) are enveloped viruses and rely on their nucleocapsid N protein to incorporate the positive-stranded genomic RNA into the virions. CoV N proteins form oligomers but the mechanism and relevance underlying their multimerizat
Externí odkaz:
https://doaj.org/article/1bd9db3283e34102b0ac19f4492e089d
Autor:
Franziska Kriegenburg, Visnja Jakopec, Esben G Poulsen, Sofie Vincents Nielsen, Assen Roguev, Nevan Krogan, Colin Gordon, Ursula Fleig, Rasmus Hartmann-Petersen
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004140 (2014)
Cells are regularly exposed to stress conditions that may lead to protein misfolding. To cope with this challenge, molecular chaperones selectively target structurally perturbed proteins for degradation via the ubiquitin-proteasome pathway. In mammal
Externí odkaz:
https://doaj.org/article/db040936062a4f239db2958846baa9e4
Autor:
Louise Madsen, Franziska Kriegenburg, Andrea Vala, Diana Best, Søren Prag, Kay Hofmann, Michael Seeger, Ian R Adams, Rasmus Hartmann-Petersen
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25061 (2011)
The protein known as p97 or VCP in mammals and Cdc48 in yeast is a versatile ATPase complex involved in several biological functions including membrane fusion, protein folding, and activation of membrane-bound transcription factors. In addition, p97
Externí odkaz:
https://doaj.org/article/090fa9b348664e19ae30ec0d4912d5d0
Autor:
Pablo Sánchez-Martín, Franziska Kriegenburg, Ludovico Alves, Julius Adam, Jana Elsaesser, Riccardo Babic, Hector Mancilla, Mariya Licheva, Georg Tascher, Christian Münch, Stefan Eimer, Claudine Kraft
Publikováno v:
Journal of Cell Science. 136
Autophagy is a catabolic process during which cytosolic material is enwrapped in a newly formed double-membrane structure called the autophagosome, and subsequently targeted for degradation in the lytic compartment of the cell. The fusion of autophag
Autor:
Henning Arlt, Babu Raman, Yasmina Filali-Mouncef, Yan Hu, Alexandre Leytens, Ralph Hardenberg, Rodrigo Guimarães, Franziska Kriegenburg, Muriel Mari, Iwona I. Smaczynska-de Rooij, Kathryn R. Ayscough, Jörn Dengjel, Christian Ungermann, Fulvio Reggiori
Publikováno v:
Arlt, H, Raman, B, Filali-Mouncef, Y, Hu, Y, Leytens, A, Hardenberg, R, Guimarães, R, Kriegenburg, F, Mari, M, Smaczynska-de Rooij, I I, Ayscough, K R, Dengjel, J, Ungermann, C & Reggiori, F 2023, ' The dynamin Vps1 mediates Atg9 transport to the sites of autophagosome formation ', The Journal of Biological Chemistry, vol. 299, no. 5, 104712 . https://doi.org/10.1016/j.jbc.2023.104712
Autophagy is a key process in eukaryotes to maintain cellular homeostasis by delivering cellular components to lysosomes/vacuoles for degradation and reuse of the resulting metabolites. Membrane rearrangements and trafficking events are mediated by t
Publikováno v:
Kriegenburg, F, Ungermann, C & Reggiori, F 2018, ' Coordination of Autophagosome-Lysosome Fusion by Atg8 Family Members ', Current biology : CB, vol. 28, no. 8, pp. R512-R518 . https://doi.org/10.1016/j.cub.2018.02.034
Macroautophagy is a conserved intracellular lysosomal degradative pathway, vital for the maintenance of cellular homeostasis. It is characterized by double-membrane vesicles called autophagosomes, which sequester the cytoplasmic material destined for
Publikováno v:
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
Biochimica et Biophysica Acta. Molecular Cell Research
Biochimica et Biophysica Acta. Molecular Cell Research
Autophagy is a degradative pathway during which autophagosomes are formed that enwrap cytosolic material destined for turnover within the lytic compartment. Autophagosome biogenesis requires controlled lipid and membrane rearrangements to allow the f
Publikováno v:
Cell Cycle
Autophagy is a degradative pathway in which cytosolic material is enwrapped within double membrane vesicles, so-called autophagosomes, and delivered to lytic organelles. SNARE (Soluble N-ethylmaleimide sensitive factor attachment protein receptor) pr