Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Franziska Kranz"'
Autor:
Steffen Grampp, James L. Platt, Victoria Lauer, Rafik Salama, Franziska Kranz, Viviana K. Neumann, Sven Wach, Christine Stöhr, Arndt Hartmann, Kai-Uwe Eckardt, Peter J. Ratcliffe, David R. Mole, Johannes Schödel
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Genome-wide association studies have identified multiple loci associated with the risk of developing renal cancer. Here, the authors show that one of these loci generates open chromatin, which enhances the binding of HIF and HIF-mediated transactivat
Externí odkaz:
https://doaj.org/article/fe92f998e7f14012877889b0b60dd9cb
Autor:
Steffen Grampp, Virginia Schmid, Rafik Salama, Victoria Lauer, Franziska Kranz, James L Platt, James Smythies, Hani Choudhry, Margarete Goppelt-Struebe, Peter J Ratcliffe, David R Mole, Johannes Schödel
Publikováno v:
PLoS Genetics, Vol 13, Iss 7, p e1006872 (2017)
Un-physiological activation of hypoxia inducible factor (HIF) is an early event in most renal cell cancers (RCC) following inactivation of the von Hippel-Lindau tumor suppressor. Despite intense study, how this impinges on cancer development is incom
Externí odkaz:
https://doaj.org/article/6b09644ca2b74a97a5428c0dec856c48
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 11, p e1005169 (2016)
G protein coupled receptors (GPCRs) allow for the transmission of signals across biological membranes. For a number of GPCRs, this signaling was shown to be coupled to prior dimerization of the receptor. The chemokine receptor type 4 (CXCR4) was repo
Externí odkaz:
https://doaj.org/article/b0b79a29ff334d2a878f7bf2991fa45b
Autor:
Franziska Kranz, Johannes Schödel, Véronique N. Lafleur, Steffen Grampp, Olivia Lombardi, Mathew L. Coleman, Hani Choudhry, David R. Mole, Atsushi Yamamoto, Bernd Wullich, Victoria Lauer, James L. Platt, Peter J. Ratcliffe, Arndt Hartmann
Publikováno v:
The Journal of Biological Chemistry
Hypoxia-inducible transcription factors (HIFs) directly dictate the expression of multiple RNA species including novel and as yet uncharacterized long noncoding transcripts with unknown function. We used pan-genomic HIF-binding and transcriptomic dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae06e8b7d0d2484753351529a17cfe6e
https://pubmed.ncbi.nlm.nih.gov/31690629
https://pubmed.ncbi.nlm.nih.gov/31690629
Autor:
Rafik Salama, David R. Mole, Christine Stöhr, Johannes Schödel, Kai-Uwe Eckardt, Franziska Kranz, Arndt Hartmann, Victoria Lauer, James L. Platt, Steffen Grampp, Sven Wach, Peter J. Ratcliffe, Viviana K. Neumann
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Clear cell renal cell carcinoma (ccRCC) is characterized by loss of function of the von Hippel–Lindau tumour suppressor (VHL) and unrestrained activation of hypoxia-inducible transcription factors (HIFs). Genetic and epigenetic determinants have an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dbce88f0b4bc036825e1cd8979ad7a1
https://ora.ox.ac.uk/objects/uuid:a1c166e7-07a8-4a26-8eb8-0e65500dcd8c
https://ora.ox.ac.uk/objects/uuid:a1c166e7-07a8-4a26-8eb8-0e65500dcd8c
Autor:
Christoph Buchenau, Franziska Kranz, Marc Stamminger, Kai Selgrad, Magdalena Martinek, Alexander Lier, Michael Guthe, Henry Schäfer
Publikováno v:
ACM Transactions on Graphics. 36:1
Parametric surfaces are an essential modeling tool in computer aided design and movie production. Even though their use is well established in industry, generating ray-traced images adds significant cost in time and memory consumption. Ray tracing su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f251fa5e5b9d3727a04145ce535495
https://doi.org/10.1145/3072959.3126820
https://doi.org/10.1145/3072959.3126820