Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Franziska Kässner"'
Autor:
Franziska Kässner, Anna Kirstein, Norman Händel, Gordian L. Schmid, Kathrin Landgraf, Antje Berthold, Astrid Tannert, Michael Schaefer, Martin Wabitsch, Wieland Kiess, Antje Körner, Antje Garten
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 290-301 (2020)
Few human cell strains are suitable and readily available as in vitro adipocyte models. We used resected lipoma tissue from a patient with germline phosphatase and tensin homolog (PTEN) haploinsufficiency to establish a preadipocyte cell strain terme
Externí odkaz:
https://doaj.org/article/708df9101bfa40b88a6eea31fcb2ba08
Autor:
Antje Garten, Antje Körner, Jürgen Kratzsch, Franziska Wilhelm, Andreas Laner, Franziska Kässner, Gordian L. Schmid, Martin Wabitsch, Wieland Kiess
Publikováno v:
Growth Hormone & IGF Research. 25:115-120
Objective Insulin-like-growth factor binding protein 2 (IGFBP-2) is thought to be a marker for the phosphatase and tensin homolog (PTEN) status and activity of the phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway.
Autor:
Andreas Laner, Frank Kowalzik, Adrian Viehweger, Franziska Wilhelm, Susanne Schuster, Gordian L. Schmid, Norman Händel, Wieland Kiess, Fred-P. Zepp, Wolfgang Hirsch, Jürgen Kratzsch, Franziska Kässner, Antje Körner, Sven Starke, Holm H. Uhlig, Antje Garten
Publikováno v:
Pediatric Research. 75:527-534
Background: Phosphatase and tensin homolog (PTEN) hamartoma tumor syndrome (PHTS) is caused by germ line mutations in the PTEN gene. Symptoms include cancer pre- disposition, immune deviations, and lipomas/lipomatosis. No causal standard therapy is a
Autor:
Norman Händel, Franziska Kässner, Antje Garten, Wieland Kiess, Susanne Schuster, Jenny Leipert, Antje Körner
Publikováno v:
Nutrition and cancer. 68(2)
Patients with phosphatase and tensin homolog (PTEN) hamartoma tumor syndrome and germline mutations in PTEN frequently develop lipomatosis, for which there is no standard treatment. Rapamycin was shown to reduce the growth of lipoma cells with hetero