Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Franziska Jarczowski"'
Autor:
Gwenn Waerlop, Yorick Janssens, Bart Jacobs, Franziska Jarczowski, André Diessner, Geert Leroux-Roels, Victor Klimyuk, Isabel Leroux-Roels, Frank Thieme
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The development of an efficacious vaccine against norovirus is of paramount importance given its potential to reduce the global burden of norovirus-associated morbidity and mortality. Here, we report a detailed immunological analysis of a phase I, do
Externí odkaz:
https://doaj.org/article/f7335b481858407fbb8da1fd8c01564b
Autor:
Isabel Leroux-Roels, Cathy Maes, Jasper Joye, Bart Jacobs, Franziska Jarczowski, André Diessner, Yorick Janssens, Gwenn Waerlop, Kirsi Tamminen, Suvi Heinimäki, Vesna Blazevic, Geert Leroux-Roels, Victor Klimyuk, Hiroshi Adachi, Kazuyuki Hiruta, Frank Thieme
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Noroviruses (NoV) are the leading cause of epidemic acute gastroenteritis in humans worldwide and a safe and effective vaccine is needed. Here, a phase I, double-blind, placebo-controlled clinical trial was performed in 60 healthy adults, 18 to 40 ye
Externí odkaz:
https://doaj.org/article/bb6df2d5e1e744729c3ccc75dafbda24
Autor:
Daniel Tusé, Maria Malm, Kirsi Tamminen, André Diessner, Frank Thieme, Franziska Jarczowski, Vesna Blazevic, Victor Klimyuk
Publikováno v:
Vaccine. 40(7)
Noroviruses (NoV) are the leading cause of epidemic acute gastroenteritis in humans worldwide. A safe and effective vaccine that prevents NoV infection or minimizes NoV disease burden is needed, especially for children and the elderly who are particu
Autor:
Maurizio Bendandi, Ascensión López-Díaz de Cerio, Fernando Pastor, Susana Inogés, Mario Martínez Soldevilla, Helena Villanueva, Arianne González, Patricia Rubio, Franziska Jarczowski, Victor Klimyuk
Publikováno v:
Journal of Vaccines, Immunology and Immunopathology. 3
Autor:
Gunter Fischer, Frank Erdmann, Günther Jahreis, Angelika Schierhorn, Franziska Jarczowski, Frank Edlich
Publikováno v:
Journal of Biological Chemistry. 284:766-773
FKBP36 has been previously shown to be a crucial factor in spermatogenesis because of its interplay with the synaptonemal complex protein SCPI. Here we show that beyond this function, FKBP36 forms complexes with glyceraldehyde-3-phosphate dehydrogena
Autor:
Frank Erdmann, Frank Edlich, Marie-Christine Moutty, Matthias Weiwad, Gunter Fischer, Franziska Jarczowski
Publikováno v:
Journal of Biological Chemistry. 282:15341-15348
FKBP38 is a negative effector of the anti-apoptotic Bcl-2 protein in neuroblastoma cells. The interaction with Bcl-2 and the enzyme activity of FKBP38 depend on prior binding of calmodulin-Ca(2+) (CaM-Ca(2+)) at high Ca(2+) concentrations. The FKBP38
Autor:
Anatoli Giritch, Yuri Gleba, Daniel Tuse, Anett Stephan, Chad H. Stahl, Ulrike Bettmann, Franziska Jarczowski, Simone Hahn, Anne-Katrin Paschke, Luisa Bortesi, Steve Schulz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(40)
Enterohemorrhagic Escherichia coli (EHEC) is one of the leading causes of bacterial enteric infections worldwide, causing ∼100,000 illnesses, 3,000 hospitalizations, and 90 deaths annually in the United States alone. These illnesses have been linke
Autor:
Daniel Tuse, Yuri Gleba, Carlos Becerra, Shan Pandya, Dieter Krause, Robert H. Collins, Romy Kandzia, Nora Ku, Franziska Jarczowski, Julian K.-C. Ma, Maurizio Bendandi, John Edward Butler-Ransohoff, Nyla Langford, Frank Thieme, Fernando Pastor, Ascensión López-Díaz de Cerio, Susana Inoges Sancho, Victor Klimyuk
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2015 (2015)
BioMed Research International, Vol 2015 (2015)
We report the first evaluation of plant-made conjugate vaccines for targeted treatment of B-cell follicular lymphoma (FL) in a Phase I safety and immunogenicity clinical study. Each recombinant personalized immunogen consisted of a tumor-derived, pla
Autor:
Marie-Christine Moutty, Werner Schmidt, Gunter Fischer, Frank Edlich, Franziska Jarczowski, Dirk Wildemann, Susann Kilka, Christian Lücke, Frank Striggow, Günther Jahreis, Matthias Weiwad
Publikováno v:
Journal of Biological Chemistry. 281:14961-14970
FK506 and FK506-derived inhibitors of the FK506-binding protein (FKBP)-type peptidylprolyl cis/trans-isomerases (PPIase) display potent neuroprotective and neuroregenerative properties in various neurodegeneration models, showing the importance of ne
Autor:
Frank Edlich, Franziska Jarczowski, Frank Erdmann, Jens-Ulrich Rahfeld, Jörg Fanghänel, Gunter Fischer, Matthias Weiwad
Publikováno v:
The EMBO Journal. 24:2688-2699
FKBP-type peptidyl prolyl cis/trans isomerases (PPIases) are folding helper enzymes involved in the control of functional regrowth of damaged sciatic, cortical cholinergic, dopaminergic and 5-HT neurones. Here, we show that the constitutively inactiv