Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Franziska Hausig"'
Autor:
Friederike Richter, Prosper Mapfumo, Liam Martin, Jana I. Solomun, Franziska Hausig, Jochen J. Frietsch, Thomas Ernst, Stephanie Hoeppener, Johannes C. Brendel, Anja Traeger
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Although there has been substantial progress in the research field of gene delivery, there are some challenges remaining, e.g. there are still cell types such as primary cells and suspension cells (immune cells) known to be difficult to tran
Externí odkaz:
https://doaj.org/article/83f2b0a9f25f47e8b38855a8890e319d
Autor:
Laura Vasilica Arsenie, Franziska Hausig, Carolin Kellner, Johannes C. Brendel, Patrick Lacroix-Desmazes, Vincent Ladmiral, Sylvain Catrouillet
Publikováno v:
Molecules, Vol 27, Iss 13, p 4233 (2022)
Thermo-responsive hydrophilic polymers, including those showing tuneable lower critical solution temperature (LCST), represent a continuous subject of exploration for a variety of applications, but particularly in nanomedicine. Since biological pH ch
Externí odkaz:
https://doaj.org/article/7d6f25e7a66a4f21928bb3140412098e
Autor:
Nadine Urban, Dimitrios Tsitsipatis, Franziska Hausig, Katrin Kreuzer, Katrin Erler, Vanessa Stein, Michael Ristow, Holger Steinbrenner, Lars-Oliver Klotz
Publikováno v:
Redox Biology, Vol 11, Iss , Pp 502-515 (2017)
The redox environment in cells and organisms is set by low-molecular mass and protein-bound thiols, with glutathione (GSH) representing a major intracellular redox buffer. Subtle thiol oxidation elicits signal transduction processes and adaptive resp
Externí odkaz:
https://doaj.org/article/1cd7590a19e2427fa071d476d08879eb
Autor:
Franziska Hausig‐Punke, Gregor Dekevic, Fabian H. Sobotta, Jana I. Solomun, Friederike Richter, Denise Salzig, Anja Traeger, Johannes C. Brendel
Publikováno v:
Macromolecular Bioscience. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51fa987b3e1c990cd0af31f3f3c81f77
https://doi.org/10.1002/mabi.202370016
https://doi.org/10.1002/mabi.202370016
Autor:
Franka V. Gruschwitz, Franziska Hausig, Philipp Schüler, Julian Kimmig, Stephanie Hoeppener, David Pretzel, Ulrich S. Schubert, Sylvain Catrouillet, Johannes C. Brendel
Publikováno v:
Chemistry of Materials. 34:2206-2217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f28d5ee3fd7fc46ef28cc4a293b4a5b8
https://doi.org/10.1021/acs.chemmater.1c03931
https://doi.org/10.1021/acs.chemmater.1c03931
Autor:
Friederike Richter, Franziska Hausig, Anja Traeger, Fabian H. Sobotta, Johannes C. Brendel, Dominic O. Harz
Publikováno v:
ACS Applied Materials & Interfaces. 13:35233-35247
Responsive polymers, which become protonated at decreasing pH, are considered a milestone in the development of synthetic cell entry vectors. Exact correlations between their properties and their ability to escape the endosome, however, often remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b991ea4b14912e565de4b6e189cf32a4
https://doi.org/10.1021/acsami.1c00829
https://doi.org/10.1021/acsami.1c00829
Publikováno v:
Macromolecular Bioscience. 22:2270027
Crossing the cellular membrane and delivering active pharmaceuticals or biologicals into the cytosol of cells is an essential step in the development of nanomedicines. One of the most important intracellular processes regarding the cellular uptake of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b5d0c495c51af6f42bf58e813c58dc
https://doi.org/10.1002/mabi.202270027
https://doi.org/10.1002/mabi.202270027
Autor:
Friederike Richter, Ivo Nischang, Anja Traeger, Prosper Mapfumo, Gizem Cinar, Franziska Hausig, Liam Martin, Stephanie Hoeppener, Elisabeth Moek, Jana I. Solomun
Publikováno v:
International journal of pharmaceutics. 593
Cationic polymers are promising gene delivery vectors due to their ability to bind and protect genetic material. The introduction of hydrophobic moieties into cationic polymers can further improve the vector efficiency, but common formulations of hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62f9e1cccdb8eb48ea418fc7510fea9
https://pubmed.ncbi.nlm.nih.gov/33246046
https://pubmed.ncbi.nlm.nih.gov/33246046
Autor:
Friederike Richter, Anja Traeger, Elisabeth Moek, Franziska Hausig, Liam Martin, Katharina Leer, Johannes C. Brendel
Publikováno v:
Journal of materials chemistry. B. 8(23)
The use of genetic material by non-viral transfer systems is still in its initial stages, but there are high expectations for the development of targeted therapies. However, nucleic acids cannot enter cells without help, they must be well protected t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4ae8478f43c4ce82bb0356823d2d1a
https://pubmed.ncbi.nlm.nih.gov/32319993
https://pubmed.ncbi.nlm.nih.gov/32319993
Autor:
Johannes C. Brendel, Franziska Hausig, Stephanie Hoeppener, Ulrich S. Schubert, Dominic O. Harz, Fabian H. Sobotta
Publikováno v:
Polymer Chemistry. 9:1593-1602
The increased levels of reactive oxygen species (ROS) such as hydrogen peroxide in inflamed or cancerous tissue represent a promising trigger for the local and selective release of drugs at the affected areas. Despite new developments in the field of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f197bf01ad8a0830f44c674064702d7
https://doi.org/10.1039/c7py01859b
https://doi.org/10.1039/c7py01859b