Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Franziska Fimm-Todt"'
Autor:
Franziska Fimm-Todt, Ezgi Dikici, Katharina Schaich, Oliver Siedentopf, Joachim Lauterwasser, Daniel Feger, Jan Erik Ehlert
Publikováno v:
Cancer Research. 83:549-549
The proto-oncogene KRas is a well-described small GTPase that functions as a molecular switch for major physiological signaling pathways involved in cell proliferation, differentiation and survival. It has been shown that activating mutations in KRas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21df95fb8100aa8fe9dd789e5a1485c0
https://doi.org/10.1158/1538-7445.am2023-549
https://doi.org/10.1158/1538-7445.am2023-549
Autor:
Frank Edlich, Franziska Fimm-Todt, Martin van der Laan, Joachim Lauterwasser, Hugo Falquez-Medina, Katelyn O'Neill, Günther Jahreis, Xu Luo, Aline Oelgeklaus, Kathrin Funk, Ralf M. Zerbes, Annabell Schreiner, Ramona Klesse
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Receptor–ligand interactions on the cell surface or intrinsic stress signals can commit mammalian cells to apoptosis. In this study, we discover how hexokinases confer resistance to receptor-mediated apoptosis through specific inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5236e4916202a28d39dee358d43b6c30
http://europepmc.org/articles/PMC8379972
http://europepmc.org/articles/PMC8379972
Autor:
Franziska Fimm-Todt, Joachim Lauterwasser, Eva-Maria Egenter, Christian Weber, Daniel Feger, Katharina Schaich, Sarah Ulrich, Oliver Siedentopf, Frank Totzke, Michael Kubbutat, Jan Erik Ehlert
Publikováno v:
Cancer Research. 82:4072-4072
Leucin-rich repeat kinase 2 (LRRK2) plays an important role in the onset of sporadic as well as familial Parkinson’s disease. Pathogenic gain-of-function mutations of LRRK2 are associated with aberrant LRRK2 hyperactivity which results in neurotoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81b543e5f98d938f8d5cc1cd827e15f1
https://doi.org/10.1158/1538-7445.am2022-4072
https://doi.org/10.1158/1538-7445.am2022-4072
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1877
BCL-2 proteins control stress-dependent commitment to the programmed cell death apoptosis. In nonapoptotic cells the proapoptotic BCL-2 proteins BAX and BAK but also prosurvival family members, like BCL-x
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe1e01454d2902114d68f5bb83366fcb
https://pubmed.ncbi.nlm.nih.gov/30536004
https://pubmed.ncbi.nlm.nih.gov/30536004
Publikováno v:
Methods in Molecular Biology ISBN: 9781493988600
BCL-2 proteins control stress-dependent commitment to the programmed cell death apoptosis. In nonapoptotic cells the proapoptotic BCL-2 proteins BAX and BAK but also prosurvival family members, like BCL-xL or MCL-1, translocate to the outer mitochond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf8c4754a18906163671cffa013f580e
https://doi.org/10.1007/978-1-4939-8861-7_10
https://doi.org/10.1007/978-1-4939-8861-7_10
