Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Franziska E. Uhl"'
Autor:
Evan T. Hoffman, Juan J. Uriarte, Franziska E. Uhl, Korin Eckstrom, Alicia E. Tanneberger, Chloe Becker, Chloe Moulin, Loredana Asarian, Laertis Ikonomou, Darrell N. Kotton, Daniel J. Weiss
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Alveolar type 2 epithelial cells (AT2s) derived from human induced pluripotent stem cells (iAT2s) have rapidly contributed to our understanding of AT2 function and disease. However, while iAT2s are primarily cultured in three-dimensional (3D
Externí odkaz:
https://doaj.org/article/628638ae4cf24318bc108d6cfcbea6a3
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114628- (2023)
Acquired cystic fibrosis transmembrane regulator (CFTR) dysfunctions have been associated with several conditions, including myocardial infarction (MI). Here, CFTR is downregulated in brain, heart, and lung tissue and associates with inflammation and
Externí odkaz:
https://doaj.org/article/7fe8dbd075dc4dd78d3c8ce7e0c2d3a6
Autor:
Lotte Vanherle, Darcy Lidington, Franziska E. Uhl, Saskia Steiner, Stefania Vassallo, Cecilia Skoug, Joao M.N. Duarte, Sangeetha Ramu, Lena Uller, Jean-François Desjardins, Kim A. Connelly, Steffen-Sebastian Bolz, Anja Meissner
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104384- (2022)
Summary: Background: Cognitive impairment is a serious comorbidity in heart failure patients, but effective therapies are lacking. We investigated the mechanisms that alter hippocampal neurons following myocardial infarction (MI). Methods: MI was ind
Externí odkaz:
https://doaj.org/article/e8c849e59b7542508bc162f64d7699da
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Heart failure (HF) affects 64 million people worldwide. Despite advancements in prevention and therapy, quality of life remains poor for many HF patients due to associated target organ damage. Pulmonary manifestations of HF are well-established. Howe
Externí odkaz:
https://doaj.org/article/132c135d02654ed594a1fc9b09aa037d
Autor:
Darcy Lidington, PhD, Jessica C. Fares, MSc, Franziska E. Uhl, PhD, Danny D. Dinh, MSc, Jeffrey T. Kroetsch, PhD, Meghan Sauvé, PhD, Firhan A. Malik, PhD, Frank Matthes, PhD, Lotte Vanherle, MSc, Arman Adel, BSc, Abdul Momen, MD, PhD, Hangjun Zhang, MD, Roozbeh Aschar-Sobbi, PhD, Warren D. Foltz, PhD, Hoyee Wan, BSc, Manabu Sumiyoshi, MD, R. Loch Macdonald, MD, PhD, Mansoor Husain, MD, Peter H. Backx, PhD, DVM, Scott P. Heximer, PhD, Anja Meissner, PhD, Steffen-Sebastian Bolz, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 940-958 (2019)
Summary: Heart failure (HF) and subarachnoid hemorrhage (SAH) chronically reduce cerebral perfusion, which negatively affects clinical outcome. This work demonstrates a strong relationship between cerebral artery cystic fibrosis transmembrane conduct
Externí odkaz:
https://doaj.org/article/aa194954f9a94652a93d9a32f78df8cb
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Mounting evidence indicates that the presence of cardiovascular disease (CVD) and risk factors elevates the incidence of cognitive impairment (CI) and dementia. CVD and associated decline in cardiovascular function can impair cerebral blood flow (CBF
Externí odkaz:
https://doaj.org/article/1aa290fcab9948cc98976c3ec7a762f1
Autor:
Isaac Almendros, Hani N. Alsafadi, Deniz Bölükbas, Jennifer J.P. Collins, Paula Duch, Eva M. Garrido-Martin, Nicolas Kahn, Theodoros Karampitsakos, Irma Mahmutovic Persson, Argyrios Tzouvelekis, Franziska E. Uhl, Sabine Bartel
Publikováno v:
Breathe, Vol 14, Iss 2, Pp e78-e83 (2018)
Externí odkaz:
https://doaj.org/article/5b8936bec1c143608407bb9d1bda7f32
Autor:
Ishna Sharma, Benefsha Mohammed, Jessica Louie, Franziska E. Uhl, Jacob Dearborn, Patrick C. Lee, Tovah Moss, John Garner, Nathan Gasek, Juan J. Uriarte, Heon E. Park, Zachary Phillips, Alexander Riveron, Robert A. Pouliot, Christine Finck, Todd Jensen, Daniel J. Weiss
Publikováno v:
Acta Biomater
Pleural and tracheal injuries remain significant problems, and an easy to use, effective pleural or tracheal sealant would be a significant advance. The major challenges are requirements for adherence, high strength and elasticity, dynamic durability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f204f1d2d75f42da16573d3982e2432
https://doi.org/10.1016/j.actbio.2021.06.048
https://doi.org/10.1016/j.actbio.2021.06.048
Autor:
Evan T. Hoffman, Franziska E. Uhl, Loredana Asarian, Bin Deng, Chloe Becker, Juan J. Uriarte, Isaac Downs, Brad Young, Daniel J. Weiss
Publikováno v:
Biomaterials. 293
Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF), are characterized by regional extracellular matrix (ECM) remodeling which contributes to disease progression. Previous proteomic stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a325cb4e42c2646b0315f9e33f5df01
https://pubmed.ncbi.nlm.nih.gov/36580718
https://pubmed.ncbi.nlm.nih.gov/36580718
Autor:
Anders Malmström, Franziska E. Uhl, Fuming Zhang, Daniel J. Weiss, Robert J. Linhardt, Gunilla Westergren-Thorsson, Juan J. Uriarte, Ke Xia, Yilan Ouyang, Oskar Hallgren, Robert A. Pouliot, Xiaorui Han, Sara Rolandsson Enes
Publikováno v:
Acta Biomater
Despite progress in use of decellularized lung scaffolds in ex vivo lung bioengineering schemes, including use of gels and other materials derived from the scaffolds, the detailed composition and functional role of extracellular matrix (ECM) proteogl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3724a3074ada7563c61ce9a09406a20
https://doi.org/10.1016/j.actbio.2019.11.029
https://doi.org/10.1016/j.actbio.2019.11.029