Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Franziska Dittrich-Domergue"'
Autor:
Malak Alannan, Hala Fatrouni, Véronique Trézéguet, Franziska Dittrich-Domergue, Patrick Moreau, Géraldine Siegfried, Benjamin Liet, Abdel-Majid Khatib, Christophe F. Grosset, Bassam Badran, Hussein Fayyad-Kazan, Aksam J. Merched
Publikováno v:
Cells, Vol 12, Iss 1, p 62 (2022)
Deregulated lipid metabolism is a common feature of liver cancers needed to sustain tumor cell growth and survival. We aim at taking advantage of this vulnerability and rewiring the oncogenic metabolic hub by targeting the key metabolic player pro-pr
Externí odkaz:
https://doaj.org/article/4663be7435534a34a53819485f818f91
Autor:
Malak Alannan, Véronique Trézéguet, Nivea Dias Amoêdo, Rodrigue Rossignol, Walid Mahfouf, Hamid Reza Rezvani, Franziska Dittrich-Domergue, Patrick Moreau, Sabrina Lacomme, Etienne Gontier, Christophe F. Grosset, Bassam Badran, Hussein Fayyad-Kazan, Aksam J. Merched
Publikováno v:
Cancers, Vol 15, Iss 1, p 3 (2022)
Alterations in lipid handling are an important hallmark in cancer. Our aim here is to target key metabolic enzymes to reshape the oncogenic lipid metabolism triggering irreversible cell breakdown. We targeted the key metabolic player proprotein conve
Externí odkaz:
https://doaj.org/article/c8f46b1e53a741589da3b2de512778b4
Autor:
Yoann Millerioux, Muriel Mazet, Guillaume Bouyssou, Stefan Allmann, Tiila-Riikka Kiema, Eloïse Bertiaux, Laetitia Fouillen, Chandan Thapa, Marc Biran, Nicolas Plazolles, Franziska Dittrich-Domergue, Aline Crouzols, Rik K Wierenga, Brice Rotureau, Patrick Moreau, Frédéric Bringaud
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1007116 (2018)
De novo biosynthesis of lipids is essential for Trypanosoma brucei, a protist responsible for the sleeping sickness. Here, we demonstrate that the ketogenic carbon sources, threonine, acetate and glucose, are precursors for both fatty acid and sterol
Externí odkaz:
https://doaj.org/article/9b8c7166f68b4ddd91c300754abc93b5
Autor:
Valérie Wattelet-Boyer, Marina Le Guédard, Franziska Dittrich-Domergue, Lilly Maneta-Peyret, Verena Kriechbaumer, Yohann Boutté, Jean-Jacques Bessoule, Patrick Moreau
Publikováno v:
Journal of experimental botany. 73(5)
Phosphatidic acid (PA) and lysophosphatidic acid acyltransferases (LPAATs) might be critical for the secretory pathway. Four extra-plastidial LPAATs (LPAAT2, 3, 4, and 5) were identified in Arabidopsis thaliana. These AtLPAATs display a specific enzy
Publikováno v:
Applied Microbiology and Biotechnology
Applied Microbiology and Biotechnology, Springer Verlag, 2018, 102 (9), pp.4063-4074. ⟨10.1007/s00253-018-8878-8⟩
Applied Microbiology and Biotechnology, Springer Verlag, 2018, 102 (9), pp.4063-4074. ⟨10.1007/s00253-018-8878-8⟩
Wax synthases are involved in the biosynthesis of wax esters, lipids with great industrial potential. Here, we heterologously expressed the native wax synthase MhWS2 from Marinobacter hydrocarbonoclasticus in Saccharomyces cerevisiae and performed co
Autor:
René Lessire, Patrick Moreau, Frédéric Domergue, Sten Stymne, Franziska Dittrich-Domergue, Jérôme Joubès
Publikováno v:
Journal of Biological Chemistry. 289:21984-21994
The biosynthesis of ether lipids and wax esters requires as precursors fatty alcohols, which are synthesized by fatty acyl reductases (FARs). The presence of ether glycerolipids as well as branched wax esters has been reported in several free-living
Autor:
Owen Rowland, Ian P. Pulsifer, Frances Tran, Micaëla G. Chacón, Ashley E. Fournier, Frédéric Domergue, Franziska Dittrich-Domergue
Publikováno v:
Journal of Biological Chemistry. 288:30345-30355
Fatty alcohols play a variety of biological roles in all kingdoms of life. Fatty acyl reductase (FAR) enzymes catalyze the reduction of fatty acyl-coenzyme A (CoA) or fatty acyl-acyl carrier protein substrates to primary fatty alcohols. FAR enzymes h
Autor:
Franziska Dittrich-Domergue, Frédéric Domergue, Jérôme Joubès, Owen Rowland, René Lessire, Sabine Scandola, Sollapura J. Vishwanath, Ian P. Pulsifer, Stéphanie Pascal, Dylan K. Kosma
Publikováno v:
Plant Physiology
Plant Physiology, American Society of Plant Biologists, 2013, 163 (3), pp.1118-1132. ⟨10.1104/pp.113.224410⟩
Plant Physiology, American Society of Plant Biologists, 2013, 163 (3), pp.1118-1132. ⟨10.1104/pp.113.224410⟩
Suberin is found in a variety of tissues, such as root endoderms and periderms, storage tuber periderms, tree cork layer, and seed coats. It acts as a hydrophobic barrier to control the movement of water, gases, and solutes as well as an antimicrobia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad27ed3df4b8779b4b8db2f235fabae9
https://hal.inrae.fr/hal-02650729
https://hal.inrae.fr/hal-02650729