Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Franziska, Herster"'
Autor:
Petros Christopoulos, Franziska Herster, Petra Hoffknecht, Markus Falk, Markus Tiemann, Hans-Georg Kopp, Andre Althoff, Anja Stammberger, Eckart Laack
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) represent first-line standard of care in unresectable EGFR mutation-positive (EGFRm+) non-small cell lung cancer (NSCLC). However, 10–20% of patients with EGFRm+ NSCLC have u
Externí odkaz:
https://doaj.org/article/d9d647cfc3ce49f18e8635c29acf8bc3
Autor:
Franziska Herster, Zsofia Bittner, Nathan K. Archer, Sabine Dickhöfer, David Eisel, Tatjana Eigenbrod, Thomas Knorpp, Nicole Schneiderhan-Marra, Markus W. Löffler, Hubert Kalbacher, Tim Vierbuchen, Holger Heine, Lloyd S. Miller, Dominik Hartl, Lukas Freund, Knut Schäkel, Martin Heister, Kamran Ghoreschi, Alexander N. R. Weber
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Antimicrobial peptide LL37 can bind nucleic acids and potentiate their sensing by endosomal TLRs. Here the authors show that LL37 binds to RNA from neutrophil extracellular traps (NETs), which amplifies inflammation and production of more LL37 and NE
Externí odkaz:
https://doaj.org/article/ea97f7082ce74177a2af8db079fd79c4
Autor:
Franziska Herster, Zsofia Bittner, Marius Cosmin Codrea, Nathan K. Archer, Martin Heister, Markus W. Löffler, Simon Heumos, Joanna Wegner, Ramona Businger, Michael Schindler, David Stegner, Knut Schäkel, Stephan Grabbe, Kamran Ghoreschi, Lloyd S. Miller, Alexander N. R. Weber
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Psoriasis is a frequent systemic inflammatory autoimmune disease characterized primarily by skin lesions with massive infiltration of leukocytes, but frequently also presents with cardiovascular comorbidities. Especially polymorphonuclear neutrophils
Externí odkaz:
https://doaj.org/article/8dd172ca07bd406789dc6f14dcbecf2e
Autor:
Anna Hafner, Ulrike Kolbe, Isabel Freund, Virginia Castiglia, Pavel Kovarik, Tanja Poth, Franziska Herster, Markus A. Weigand, Alexander N. R. Weber, Alexander H. Dalpke, Tatjana Eigenbrod
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Streptococcus pyogenes is a major human pathogen causing a variety of diseases ranging from common pharyngitis to life-threatening soft tissue infections and sepsis. Microbial nucleic acids, especially bacterial RNA, have recently been recognized as
Externí odkaz:
https://doaj.org/article/dcde18935f0e4cda96fa1835e3401b9a
Autor:
Cristiana Roggia, Sorin Armeanu-Ebinger, Axel Gschwind, Olga Seibel-Kelemen, Sonja Hertler, Ulrike Faust, Alexandra Liebmann, Tobias B. Haack, Manuela Neumann, Irina Bonzheim, Andrea Forschner, Hans-Georg Kopp, Franziska Herster, Andreas Hartkopf, Michael Bitzer, Nisar P. Malek, Ines B. Brecht, Kristina Ruhm, Yvonne Möller, Hubert Löwenheim, Stephan Ossowski, Olaf H. Rieß, Christopher Schroeder
Publikováno v:
European journal of cancer (Oxford, England : 1990). 179
Sequencing of tumour tissue with comprehensive gene panels is increasingly used to guide treatment in precision oncology. Analysis of tumour-normal pairs allows in contrast to tumour-only assessment direct discrimination between somatic and germline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164a1dd6b0fcd40e04ab63bf79c84a3b
https://pubmed.ncbi.nlm.nih.gov/36495689
https://pubmed.ncbi.nlm.nih.gov/36495689
Autor:
Löffler, Nick Seyfried, Can Yurttas, Markus Burkard, Benedikt Oswald, Alexander Tolios, Franziska Herster, Joseph Kauer, Tarkan Jäger, Ingmar Königsrainer, Karolin Thiel, Markus Quante, Hans-Georg Rammensee, Sascha Venturelli, Matthias Schwab, Alfred Königsrainer, Stefan Beckert, Markus W.
Publikováno v:
Cancers; Volume 14; Issue 5; Pages: 1158
Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) was considered a promising treatment for patients with peritoneal metastasis from colorectal cancer. However, the recently published randomized controlled PRODIGE 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::ba03fb5ecb8a9f6f6e3a3932976b37df
Autor:
Nick, Seyfried, Can, Yurttas, Markus, Burkard, Benedikt, Oswald, Alexander, Tolios, Franziska, Herster, Joseph, Kauer, Tarkan, Jäger, Ingmar, Königsrainer, Karolin, Thiel, Markus, Quante, Hans-Georg, Rammensee, Sascha, Venturelli, Matthias, Schwab, Alfred, Königsrainer, Stefan, Beckert, Markus W, Löffler
Publikováno v:
Cancers. 14(5)
Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) was considered a promising treatment for patients with peritoneal metastasis from colorectal cancer. However, the recently published randomized controlled PRODIGE 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7ef1123616078cd13648369d9f26707
https://pubmed.ncbi.nlm.nih.gov/35267468
https://pubmed.ncbi.nlm.nih.gov/35267468
Publikováno v:
The Journal of investigative dermatology. 141(6)
Platelets have long been known as mediators of hemostasis and, more recently, as mediators of thromboinflammation, although their physiopathological role has mostly been investigated in the context of disease of internal organs, such as liver and kid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ab1b1e8eb28236b474e12e830de6d1
https://pubmed.ncbi.nlm.nih.gov/33810836
https://pubmed.ncbi.nlm.nih.gov/33810836
Autor:
Sabine Dickhöfer, Oliver Hantschel, Hubert Kalbacher, Anita Delor, Franziska Herster, Jasmin Kümmerle-Deschner, Bodo Grimbacher, Carsten L. Greve, Xiao Liu, Ana Marcu, Samuel Wagner, Hao Wu, Liudmila Andreeva, Ana Tapia-Abellán, Yamel Cardona Gloria, Alexander N.R. Weber, Marta Lovotti, Eicke Latz, Michael Scharl, Markus W. Löffler, Maria Mateo Tortola, Olaf-Oliver Wolz, Nadine A. Schilling, Peter Düwell, Matthew Mangan, Sangeetha Shankar, Tzu-Hsuan Chang, Zsofia Bittner, Stefan Stevanovic, Karlotta Bosch, Francesca Bork, Marianne R. Spalinger
Publikováno v:
Journal of experimental medicine 218(11), e20201656 (2021). doi:10.1084/jem.20201656
Activity of the NLRP3 inflammasome, a critical mediator of inflammation, is controlled by accessory proteins, posttranslational modifications, cellular localization, and oligomerization. How these factors relate is unclear. We show that a well-establ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3608b1034f01b278a87ae7f4c5f83cb4
https://pubmed.ncbi.nlm.nih.gov/34554188
https://pubmed.ncbi.nlm.nih.gov/34554188
Autor:
Dominik Hartl, Thomas Knorpp, Hubert Kalbacher, Knut Schäkel, Nicole Schneiderhan-Marra, Holger Heine, Lloyd S. Miller, Sabine Dickhöfer, Zsofia Bittner, Tatjana Eigenbrod, Kamran Ghoreschi, Tim Vierbuchen, Markus W. Löffler, Nathan K. Archer, Franziska Herster, Martin Heister, Alexander N.R. Weber, Lukas Freund, David Eisel
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Psoriasis is an inflammatory skin disease with strong neutrophil (PMN) infiltration and high levels of the antimicrobial peptide, LL37. LL37 in complex with DNA and RNA is thought to initiate disease exacerbation via plasmacytoid dendritic cells. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2268dcfad4dade0ec2696a94060df3af
http://europepmc.org/articles/PMC6949246
http://europepmc.org/articles/PMC6949246