Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Franziska, Fröb"'
Autor:
Sebastian Gehlen-Breitbach, Theresa Schmid, Franziska Fröb, Gabriele Rodrian, Matthias Weider, Michael Wegner, Lina Gölz
Publikováno v:
International Journal of Oral Science, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract The cranial neural crest plays a fundamental role in orofacial development and morphogenesis. Accordingly, mutations with impact on the cranial neural crest and its development lead to orofacial malformations such as cleft lip and palate. As
Externí odkaz:
https://doaj.org/article/d879d16c5990487187ab24867ebb9e7e
Autor:
Jesse Rupprecht, Simone Reiprich, Tina Baroti, Carmen Christoph, Elisabeth Sock, Franziska Fröb, Michael Wegner
Publikováno v:
Cells, Vol 13, Iss 11, p 935 (2024)
Rapid information processing in the central nervous system requires the myelination of axons by oligodendrocytes. The transcription factor Sox2 and its close relative Sox3 redundantly regulate the development of myelin-forming oligodendrocytes, but l
Externí odkaz:
https://doaj.org/article/39676ea7020b450a9fd297057442dc2a
Autor:
Vanessa Polanetzki, Franziska Fröb, Tina Baroti, Margit Schimmel, Ernst R. Tamm, Michael Wegner
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Myelin sheath formation in the peripheral nervous system and the ensuing saltatory conduction rely on differentiated Schwann cells. We have previously shown that transition of Schwann cells from an immature into a differentiated state requir
Externí odkaz:
https://doaj.org/article/b5b50d538e6243409dff062ad7efe0bf
Autor:
Ella Ittner, Anna C. Hartwig, Olga Elsesser, Hannah M. Wüst, Franziska Fröb, Miriam Wedel, Margit Schimmel, Ernst R. Tamm, Michael Wegner, Elisabeth Sock
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The three SoxD proteins, Sox5, Sox6 and Sox13, represent closely related transcription factors with important roles during development. In the developing nervous system, SoxD proteins have so far been primarily studied in oligodendroglial ce
Externí odkaz:
https://doaj.org/article/b3e535b773874646bf0b6c01712929f9
Publikováno v:
Cells, Vol 12, Iss 12, p 1556 (2023)
Oligodendrocyte development is accompanied by defined changes in the state of chromatin that are brought about by chromatin remodeling complexes. Many such remodeling complexes exist, but only a few have been studied for their impact on oligodendrocy
Externí odkaz:
https://doaj.org/article/243e6787dfe04eeeb47dace308e96093
Autor:
Franziska Fröb, Elisabeth Sock, Ernst. R. Tamm, Anna-Lena Saur, Simone Hillgärtner, Trevor J. Williams, Toshihiro Fujii, Rikiro Fukunaga, Michael Wegner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The Ep400 chromatin remodeler determines genomic distribution of variant histones. In the current study, the authors show that loss of Ep400 in Schwann cells leads to aberrant expression of developmental regulators, and a peripheral neuropathy phenot
Externí odkaz:
https://doaj.org/article/2c01dc5a25984a1dbe35317ab8b430f2
Autor:
Nane Eiber, Franziska Fröb, Mirjam Schowalter, Christian Thiel, Christoph S. Clemen, Rolf Schröder, Said Hashemolhosseini
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Desmin, the major intermediate filament (IF) protein in muscle cells, interlinks neighboring myofibrils and connects the whole myofibrillar apparatus to myonuclei, mitochondria, and the sarcolemma. However, desmin is also known to be enriched at post
Externí odkaz:
https://doaj.org/article/6017cf1596f149c0a79ffefa7a188735
Autor:
Matthias Weider, Laura Julia Starost, Katharina Groll, Melanie Küspert, Elisabeth Sock, Miriam Wedel, Franziska Fröb, Christian Schmitt, Tina Baroti, Anna C. Hartwig, Simone Hillgärtner, Sandra Piefke, Tanja Fadler, Marc Ehrlich, Corinna Ehlert, Martin Stehling, Stefanie Albrecht, Ammar Jabali, Hans R. Schöler, Jürgen Winkler, Tanja Kuhlmann, Michael Wegner
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Oligodendrocyte differentiation is known to depend on transcription factors Sox10, Nkx2.2, and Olig2. Here, the authors show that Nfat/calcineurin signaling contributes to oligodendrocyte differentiation by relieving mutual repression of Nkx2.2 and O
Externí odkaz:
https://doaj.org/article/dc813a76f1a44fa790c36e641522a47c
Autor:
Celine Bernhardt, Elisabeth Sock, Franziska Fröb, Simone Hillgärtner, Mona Nemer, Michael Wegner
Publikováno v:
Nucleic Acids Research. 50:11509-11528
Differentiated oligodendrocytes produce myelin and thereby ensure rapid nerve impulse conduction and efficient information processing in the vertebrate central nervous system. The Krüppel-like transcription factor KLF9 enhances oligodendrocyte diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c968b7fced1737f752078b59ef7b5f
https://doi.org/10.1093/nar/gkac953
https://doi.org/10.1093/nar/gkac953
Publikováno v:
Cells; Volume 12; Issue 12; Pages: 1556
Oligodendrocyte development is accompanied by defined changes in the state of chromatin that are brought about by chromatin remodeling complexes. Many such remodeling complexes exist, but only a few have been studied for their impact on oligodendrocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::69dde7ef2c464a06ac0c8eae9378c9f8