TLR9 agonism differentially impacts human NK cell-mediated direct killing and antibody-dependent cell-mediated cytotoxicity.

Autor: Mahr AR; Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA., Bennett-Boehm MMC; Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA.; Department of Interdisciplinary Informatics, University of Nebraska at Omaha, Omaha, NE, USA., Rothemejer FH; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Weber IS; Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA., Regan AK; Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA., Franzen JQ; Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA., Bisson CR; Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA., Truong AN; Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA., Olesen R; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Schleimann MH; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark., Rauter CM; Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA., Smith AL; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA., El-Gamal D; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA.; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA., Søgaard OS; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Tolstrup M; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Denton PW; Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA. pdenton@unomaha.edu.

Publikováno v: Scientific reports [Sci Rep] 2024 Jun 25; Vol. 14 (1), pp. 14595. Date of Electronic Publication: 2024 Jun 25.