Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Franz Osl"'
Autor:
Joerg P. J. Mueller, Michael Dobosz, Nils O’Brien, Nassri Abdoush, Anna Maria Giusti, Martin Lechmann, Franz Osl, Ann-Katrin Wolf, Estibaliz Arellano-Viera, Haroon Shaikh, Markus Sauer, Andreas Rosenwald, Frank Herting, Pablo Umaña, Sara Colombetti, Thomas Pöschinger, Andreas Beilhack
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Advancing novel immunotherapy strategies requires refined tools in preclinical research to thoroughly assess drug targets, biodistribution, safety, and efficacy. Light sheet fluorescence microscopy (LSFM) offers unprecedented fast volumetric ex vivo
Externí odkaz:
https://doaj.org/article/0adbb0ea11e9407283871afd4630482d
Autor:
Mirko Thamm, Stefanie Rosenhain, Kevin Leonardic, Andreas Höfter, Fabian Kiessling, Franz Osl, Thomas Pöschinger, Felix Gremse
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Small animal micro computed tomography (μCT) is an important tool in cancer research and is used to quantify liver and lung tumors. A type of cancer that is intensively investigated with μCT is hepatocellular carcinoma (HCC). μCT scans acquire pro
Externí odkaz:
https://doaj.org/article/0938694ca31949429c3f5e9b05c8e4b7
Autor:
Joan Seoane, Pablo Umaña, Josep Tabernero, Maria Vieito, Joan Carles, Paolo Nuciforo, Josep González, Alberto Di Somma, Luis Reyes-Figueroa, Estela Pineda, Christian Klein, Marina Bacac, Sara Colombetti, Johannes Sam, Franz Osl, Joerg Mueller, Stefanie Briner, Marine Richard, Virginie Steinhart, Thomas Pöschinger, Linda Fahrni, Xavier Guardia-Reyes, Simona Casalino, Marta Cicuendez, Esteban Cordero, Francisco Martínez-Ricarte, Alba Martínez-Moreno, Isabel Cuartas, Anne Freimoser-Grundschober, Valeria Nicolini, Alexandra Arias, Ester Bonfill-Teixidor, Ester Planas-Rigol, Inja Waldhauer, Raffaella Iurlaro
Supplementary Figure from A Novel EGFRvIII T-Cell Bispecific Antibody for the Treatment of Glioblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657bca3e4a42077f3949a8e50f002546
https://doi.org/10.1158/1535-7163.22523662.v1
https://doi.org/10.1158/1535-7163.22523662.v1
Autor:
Werner Scheuer, Alnawaz Rehemtulla, Stefanie Galbán, Thomas Pöschinger, Anja Renner, Franz Osl, Thomas G. Weber
PDF file - 414KB, Supplementary Figure 2 - Fluorescence imaging after i.v. application of anti-DR5-Cy5 shows no specific antibody accumulation in the right brain hemisphere.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcc0d84f8f48b4f87daa7fa068c6203
https://doi.org/10.1158/0008-5472.22401258
https://doi.org/10.1158/0008-5472.22401258
Autor:
Werner Scheuer, Alnawaz Rehemtulla, Stefanie Galbán, Thomas Pöschinger, Anja Renner, Franz Osl, Thomas G. Weber
High-grade gliomas often possess an impaired blood–brain barrier (BBB), which allows delivery of large molecules to brain tumors. However, achieving optimal drug concentrations in brain tumors remains a significant hurdle for treating patients succ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b18e50aaeb1a76c988b5e0c2d0c73e4
https://doi.org/10.1158/0008-5472.c.6505791
https://doi.org/10.1158/0008-5472.c.6505791
Autor:
Werner Scheuer, Alnawaz Rehemtulla, Stefanie Galbán, Thomas Pöschinger, Anja Renner, Franz Osl, Thomas G. Weber
PDF file - 186KB, Supplementary Figure 4 - Antibody penetration is enhanced in U87-Luc and U251 brain xenograft tumors indicating BBB disruption.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10426563e4d90146aa6525ae9877cda9
https://doi.org/10.1158/0008-5472.22401252.v1
https://doi.org/10.1158/0008-5472.22401252.v1
Autor:
Werner Scheuer, Alnawaz Rehemtulla, Stefanie Galbán, Thomas Pöschinger, Anja Renner, Franz Osl, Thomas G. Weber
PDF file - 936KB, Supplementary Figure 3 - Apoptosis and fluorescence imaging reveal that 3.9-7.0% of anti-DR5-Cy5 given i.v. reaches subcutaneous D54-Caspase-3/7 GloSensor tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5151070826120cd2f72ac1e4bfe2156d
https://doi.org/10.1158/0008-5472.22401255.v1
https://doi.org/10.1158/0008-5472.22401255.v1
Autor:
Werner Scheuer, Alnawaz Rehemtulla, Stefanie Galbán, Thomas Pöschinger, Anja Renner, Franz Osl, Thomas G. Weber
PDF file - 75KB, Supplementary Figure 1 - Highly sensitive apoptosis imaging allows tumor detection and randomization at early time points.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353467f73632c3f8a85700dcf69e1beb
https://doi.org/10.1158/0008-5472.22401261
https://doi.org/10.1158/0008-5472.22401261
Autor:
Werner Scheuer, Alnawaz Rehemtulla, Stefanie Galbán, Thomas Pöschinger, Anja Renner, Franz Osl, Thomas G. Weber
PDF file - 63KB, Fluorescence imaging - Fluorescence imaging was used for monitoring anti-DR5-Cy5 distribution in the mouse. Cell culture and cell inoculation of U87-Luc and U251 cell lines - U87-Luc and U251 were used for additional BBB penetration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542fe777d18fc98f3898eddd0f5f2d03
https://doi.org/10.1158/0008-5472.22401243
https://doi.org/10.1158/0008-5472.22401243