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Interleukin 4 inhibits the proliferation and promotes the maturation of human leukemic early B cells
Autor:
Christian Schmitt, Franz Mentz, F Ouaaz, Jean-Jaques Guillosson, Patrice Debré, Ariane Michel, M. Djavad Mossalayi, Hélène Merle-Béral, Michel Arock
Publikováno v:
European Journal of Haematology. 51:276-281
The effects of interleukin 4 (IL-4) on human leukemic precursor B-cell lines were investigated. Recombinant IL-4 (rIL-4) was added to three acute lymphoblastic leukemia-derived pre B-cell lines: Reh, Km3 and Nalm-6. Our results show that rIL-4 signif