Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Franz Lagasse"'
Autor:
Franz Lagasse, Diana Trebicka, Andrew Ratcliffe, Stevenson Brett W, Corina Tudor, Edward Cochrane, James Hulit, Tanguy Lechertier, Tim Sparey
Publikováno v:
ACS Med Chem Lett
[Image: see text] Some marketed antibiotics can cause mitochondria dysfunction via inhibition of the mitochondrial translation process. There is great interest in exploiting such effects within a cancer setting. To enhance accumulation of antibiotics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67dba3e6a547ce09e982d2c5275fd41
https://doi.org/10.1021/acsmedchemlett.0c00632
https://doi.org/10.1021/acsmedchemlett.0c00632
Autor:
Stuart Thomas Onions, Yuki Nishimoto, Alexandre Alanio, Mihiro Sunose, Franz Lagasse, Genki Kimura, Steven L. Kelly, Thomas Colley, Diane E. Kelly, Damien Crepin, Kazuhiro Ito, Anuradha Chowdhary, Jonathan Shannon, Matthew Mcconville, John Murray, Garth Rapeport, Stéphane Bretagne, John King-Underwood, Darius Armstrong-James, Gurpreet Sehra, Andrew G. S. Warrilow, Alan Naylor, Matthew C. Fisher, Yasuo Kizawa, Pete Strong, Matthew Crittall, Josie E. Parker
Publikováno v:
Antimicrobial Agents and Chemotherapy
The antifungal effects of the novel triazole PC1244, designed for topical or inhaled administration, against Aspergillus fumigatus were tested in a range of in vitro and in vivo studies. PC1244 demonstrated potent antifungal activities against clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba0ed3696bcc429664c3cf05fb16527c
http://hdl.handle.net/10044/1/57331
http://hdl.handle.net/10044/1/57331
Publikováno v:
Tetrahedron: Asymmetry, Vol. 7, No 12 (1996) pp. 3343-3346
α,β-Ethylenic chiral acetals react regio- and stereoselectively with organolithium reagents. The obtained enol ether may be hydrolyzed into a chiral β-disubstituted aldehyde.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c770465346018eea2ffc9e270c81815f
https://doi.org/10.1016/s0957-4166(96)00438-7
https://doi.org/10.1016/s0957-4166(96)00438-7
Publikováno v:
Tetrahedron Letters. 43:5715-5717
Enantiomerically enriched O-TMS cyanohydrins have been transformed directly into O-acyl-cyanohydrins using various anhydrides or acid chlorides in the presence of catalytic amounts of scandium(III) triflate. The reaction occurs with full retention of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c10ad21e325d16ea6db5430a5e8e352
https://doi.org/10.1016/s0040-4039(02)01200-5
https://doi.org/10.1016/s0040-4039(02)01200-5
Publikováno v:
ChemInform. 28
α,β-Ethylenic chiral acetals react regio- and stereoselectively with organolithium reagents. The obtained enol ether may be hydrolyzed into a chiral β-disubstituted aldehyde.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db758798ff68bcd6e085689b2ab90133
https://doi.org/10.1002/chin.199714046
https://doi.org/10.1002/chin.199714046
Autor:
Franz Lagasse, Henri B. Kagan
Publikováno v:
ChemInform. 31
Chelating chiral diphosphines are often used as ligands of organometallic complexes. However monophosphines, or more generally ligands with one phosphorus linked to one or several heteroatom, may also be useful. This review gives the main results obt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9287ba4a6224d3a584b85bcad912ef2
https://doi.org/10.1002/chin.200032214
https://doi.org/10.1002/chin.200032214
Publikováno v:
ChemInform. 33
Enantiomerically enriched O-TMS cyanohydrins have been transformed directly into O-acyl-cyanohydrins using various anhydrides or acid chlorides in the presence of catalytic amounts of scandium(III) triflate. The reaction occurs with full retention of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dc57b7fb2f961675e7decfaa89879d5
https://doi.org/10.1002/chin.200247044
https://doi.org/10.1002/chin.200247044
Autor:
Franz Lagasse, Henri B. Kagan
Publikováno v:
Chemicalpharmaceutical bulletin. 48(3)
Chelating chiral diphosphines are often used as ligands of organometallic complexes. However monophosphines, or more generally ligands with one phosphorus linked to one or several heteroatom, may also be useful. This review gives the main results obt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a8ad2f5306d31f0813e4fb27786981
https://pubmed.ncbi.nlm.nih.gov/10726849
https://pubmed.ncbi.nlm.nih.gov/10726849
Publikováno v:
Journal of the American Chemical Society. 125:7490-7491
The evaluation of a racemic catalyst was investigated in the case of oxazaborolidine (OAB)-catalyzed borane reduction of 1,5-diphenyl-1,5-pentanedione, giving the corresponding diol. On the basis of the diastereoselectivity of the diols, it is possib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec02c5529305a6c2f7d12d90bb9000ec
https://doi.org/10.1021/ja0300315
https://doi.org/10.1021/ja0300315