Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Franz Krempler"'
Autor:
Selma M. Soyal, Thomas Felder, Simon Auer, Hannes Oberkofler, Bernhard Iglseder, Bernhard Paulweber, Silvia Dossena, Charity Nofziger, Markus Paulmichl, Harald Esterbauer, Franz Krempler, Wolfgang Patsch
Publikováno v:
Journal of Diabetes Research, Vol 2015 (2015)
The genomic region ~500 kb upstream of IRS1 has been implicated in insulin resistance, type 2 diabetes, adverse lipid profile, and cardiovascular risk. To gain further insight into this chromosomal region, we typed four SNPs in a cross-sectional coho
Externí odkaz:
https://doaj.org/article/0b571fa4bbbb4d6e99dcfec93d6abc8e
Autor:
Harald Esterbauer, Hannes Oberkofler, Yong-Ming Liu, David Breban, Emanuel Hell, Franz Krempler, Wolfgang Patsch
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 4, Pp 834-844 (1998)
Uncoupling protein-1 (UCP-1) activity in brown adipose tissue increases thermogenesis, contributes to facultative energy expenditure in humans, and has been implicated in the pathogenesis of rodent obesity. To determine genetic factors controlling UC
Externí odkaz:
https://doaj.org/article/49fca20fab364b5c81c5b43d7b7efc94
Autor:
Edith E Mueller, Waltraud Eder, Sabine Ebner, Eva Schwaiger, Danijela Santic, Tanja Kreindl, Olaf Stanger, Bernhard Paulweber, Bernhard Iglseder, Hannes Oberkofler, Richard Maier, Johannes A Mayr, Franz Krempler, Raimund Weitgasser, Wolfgang Patsch, Wolfgang Sperl, Barbara Kofler
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16455 (2011)
BackgroundThe pivotal role of mitochondria in energy production and free radical generation suggests that the mitochondrial genome could have an important influence on the expression of multifactorial age related diseases. Substitution of T to C at n
Externí odkaz:
https://doaj.org/article/02b6b0089b104c08a072bed8c1cac234
Autor:
Karl Miller, Markus Paulmichl, Penelope Hahne, Selma M. Soyal, Thomas K. Felder, Simon Auer, Wolfgang Patsch, Hannes Oberkofler, Franz Krempler
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32:1535-1544
Objective— Genetic studies implicated upstream stimulatory factor 1 (USF1) in familial combined hyperlipidemia because the rs2073658 minor allele was associated with reduced risk of familial combined hyperlipidemia and related disorders. The molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54e8ca94aaabd6255f6bdb133061213
https://doi.org/10.1161/atvbaha.112.245639
https://doi.org/10.1161/atvbaha.112.245639
Autor:
Penelope Hahne, Bernhard Paulweber, Josef R. Patsch, Selma M. Soyal, A. Sandhofer, Franz Krempler, Karl Miller, Hannes Oberkofler, Bernhard Iglseder, Wolfgang Patsch, Thomas K. Felder
Publikováno v:
Atherosclerosis. 216:374-380
Objective HDL modifying effects of cholesteryl ester transfer protein (CETP) and hepatic lipase (LIPC) depend in part on each other. We studied associations of CETP -Taq1B and -514C>T- LIPC polymorphisms with hepatic mRNA levels, and their combined e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f50e9b7ccbc0ef1f2132fb432cce467
https://doi.org/10.1016/j.atherosclerosis.2011.01.052
https://doi.org/10.1016/j.atherosclerosis.2011.01.052
Autor:
Mathias Müller, Martin Bilban, Wolfgang Patsch, Franz Krempler, Jelena Todoric, Sabine Amann, Martina Bayer, Harald Esterbauer, J. Andrew Pospisilik, Oswald Wagner, Alexander Jais, Nicole Boucheron, Josefine Lindroos, Wilfried Ellmeier, Birgit Strobl, Gerhard Prager, Raffaele Teperino
Publikováno v:
Diabetes
OBJECTIVE T cells and level of the cytokine interferon-γ (IFN-γ) are increased in adipose tissue in obesity. Hedgehog (Hh) signaling has been shown to potently inhibit white adipocyte differentiation. In light of recent findings in neurons that IFN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f447770fed8d26fe5a4b38940d21732
https://doi.org/10.2337/db10-1628
https://doi.org/10.2337/db10-1628
Autor:
Jyrki J. Eloranta, Wolfgang Patsch, Katja Klein, Franz Krempler, Jessica Mwinyi, Christoph Jüngst, Gerd A. Kullak-Ublick, Bruno Stieger
Publikováno v:
Molecular pharmacology
Organic anion transporters (OATs) are anion exchangers that transport small hydrophilic anions and diuretics, antibiotics, nonsteroidal anti-inflammatory drugs, antiviral nucleoside analogs, and antitumor drugs across membrane barriers of epithelia o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224eda3288c9f0b4bf3eb0f527fff6fd
https://doi.org/10.1124/mol.110.065201
https://doi.org/10.1124/mol.110.065201
Publikováno v:
Journal of Molecular Medicine. 87:299-306
Peroxisome proliferator-activated receptor-gamma co-activator-1 (PGC-1) alpha and -beta play pivotal roles in the regulation of intermediary metabolism. We have previously shown that PGC-1alpha-mediated upregulation of beta-cell sterol element bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab068087b5de280ff8469ca24bfb3b4
https://doi.org/10.1007/s00109-008-0425-0
https://doi.org/10.1007/s00109-008-0425-0
Autor:
H. Höffinger, Penelope Hahne, W. Strobl, Franz Krempler, F. G. Schaap, Wolfgang Patsch, Hannes Oberkofler, Selma M. Soyal, Karl Miller
Publikováno v:
Journal of internal medicine, 264(5), 452-462. Wiley-Blackwell
Objective. Apolipoprotein A-V (apoAV) contributes to the regulation of triglyceride metabolism, which plays a role in the pathogenesis of atherosclerotic diseases. We therefore ascertained determinants of hepatic APOA5 transcript and apoAV plasma lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a66dd957fee5621ae3f3dc103c09753
https://doi.org/10.1111/j.1365-2796.2008.01987.x
https://doi.org/10.1111/j.1365-2796.2008.01987.x
Autor:
Harald Esterbauer, Charity Nofziger, Thomas K. Felder, Bernhard Iglseder, Silvia Dossena, Selma M. Soyal, Wolfgang Patsch, Simon Auer, Markus Paulmichl, Franz Krempler, Hannes Oberkofler, Bernhard Paulweber
Publikováno v:
Journal of Diabetes Research
Journal of Diabetes Research, Vol 2015 (2015)
Journal of Diabetes Research, Vol 2015 (2015)
The genomic region ~500 kb upstream ofIRS1has been implicated in insulin resistance, type 2 diabetes, adverse lipid profile, and cardiovascular risk. To gain further insight into this chromosomal region, we typed four SNPs in a cross-sectional cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3ac7fa2424c66d5acb07e52513f425
http://europepmc.org/articles/PMC4451528
http://europepmc.org/articles/PMC4451528