Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Franz K. Jansen"'
Autor:
P. Carayon, Philippe Poncelet, Jean-Pierre Farcet, Franz K. Jansen, Guy Laurent, Jacques Pris, Hildur E. Blythman, Pierre Casellas
Publikováno v:
Blood. 67:1680-1687
Two leukemia patients, refractory to chemotherapy, were treated with T101-ricin A-chain immunotoxin (T101 IT). Patient 1 (T-ALL) received a single 13.5 mg dose of T101 IT IV (12-hour infusion). Patient 2 (B-CLL) was treated with a daily 25 mg dose of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4048b13852a914789392b53258339529
https://doi.org/10.1182/blood.v67.6.1680.1680
https://doi.org/10.1182/blood.v67.6.1680.1680
Autor:
Pierre Casellas, Axel A. Fauser, Franz K. Jansen, Guy Laurent, Xavier Canat, Philippe Poncelet, Olivier Gros
Publikováno v:
Blood. 65:289-297
In view of bone marrow purging before autologous transplantation in T cell malignancies, an anti-human T cell immunotoxin (IT) has been prepared by coupling ricin A-chain to the monoclonal antibody T101 that binds the T1 differentiation antigen expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a7f7e89e61039a3238018799c5407c
https://doi.org/10.1182/blood.v65.2.289.289
https://doi.org/10.1182/blood.v65.2.289.289
Autor:
Guy Laurent, Franz K. Jansen, Jean-Marie Derocq, Sophie Ravel, Pierre Casellas, Bernard Bourrie, Pierre Gros
Publikováno v:
Blood. 72:1197-1202
To maximize T-lymphocyte killing with anti-pan-T-lymphocyte immunotoxin (IT), prepared by linking ricin A-chain to monoclonal antibody (MoAb) T101 (T101-RTA IT), we have established the nature and the extent of parameters that influence the sensitivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57a11dbc070571c700b37d60a44e3ac0
https://doi.org/10.1182/blood.v72.4.1197.1197
https://doi.org/10.1182/blood.v72.4.1197.1197
Autor:
Cécile Demur, P. Poncelet, H. Vidal, Franz K. Jansen, Pierre Casellas, Guy Laurent, Axel A. Fauser, Jean-Marie Derocq
Publikováno v:
Transplantation. 44:763-769
A series of 25 different ricin A-chain immunotoxins (IT) were prepared with monoclonal antibodies reacting with several T cell antigens belonging to different clusters of differentiation (CD) to select the most appropriate immunotoxins (IT) for matur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50cc9bb33b41a4088c9302987875dff
https://doi.org/10.1097/00007890-198712000-00008
https://doi.org/10.1097/00007890-198712000-00008
Autor:
B. Bourrie, D. Dussossoy, Pierre Casellas, P. Vic, Franz K. Jansen, O. Gros, H. Vidal, P. Gros
Publikováno v:
Immunotoxins ISBN: 9781461284192
The first immunotoxins (ITs) assembled by Moolten et al. in the seventies [1, 2] were composed of antibodies linked to whole toxins such as diphtheria toxin and ricin. In order to circumvent the nonspecific binding due to the B chains, ITs with the A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a51419b660856d421631fddaa86cb101
https://doi.org/10.1007/978-1-4613-1083-9_7
https://doi.org/10.1007/978-1-4613-1083-9_7
Autor:
G. Laurent, Arthur E. Frankel, Franz K. Jansen, Andrew A. Hertler, D M Schlossman, Pierre Casellas
Publikováno v:
Immunotoxins ISBN: 9781461284192
Cancer chemotherapies, despite recent advances, are still limited because of their toxic effects and lack of efficacy on the nonproliferating fraction of malignant cells. The use of agents which could target specifically malignant cells might improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a4e4824c418497a5fb5209553990c17
https://doi.org/10.1007/978-1-4613-1083-9_27
https://doi.org/10.1007/978-1-4613-1083-9_27