Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Franz Josef Gassner"'
Autor:
Thomas Parigger PhD, Franz Josef Gassner PhD, Stephan Drothler MSc, Christian Scherhäufl MSc, Alexandra Hödlmoser MSc, Lena Schultheis MSc, Aryunni Abu Bakar MSc, Florian Huemer MD, Richard Greil MD, Roland Geisberger PhD, Lukas Weiss MD, PhD, Nadja Zaborsky PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 23 (2024)
Objectives: In this study, stool samples were evaluated for tumor mutation analysis via a targeted next generation sequencing (NGS) approach in a small patient cohort suffering from localized rectal cancer. Introduction: Colorectal cancer (CRC) cause
Externí odkaz:
https://doaj.org/article/9444f640bdc84627b111c7918a84a93d
Autor:
Marc Vaisband, Maria Schubert, Franz Josef Gassner, Roland Geisberger, Richard Greil, Nadja Zaborsky, Jan Hasenauer
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-19 (2023)
Abstract Accurate somatic variant calling from next-generation sequencing data is one most important tasks in personalised cancer therapy. The sophistication of the available technologies is ever-increasing, yet, manual candidate refinement is still
Externí odkaz:
https://doaj.org/article/6354773ffd1345a882925ecef572ccef
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208753 (2018)
Activation induced deaminase (AID) has two distinct and well defined roles, both relying on its deoxycytidine (dC) deaminating function: one as a DNA mutator and another in DNA demethylation. In chronic lymphocytic leukemia (CLL), AID was previously
Externí odkaz:
https://doaj.org/article/501cb474db334f3da5fa5d118a969bc8
Autor:
Kemal Catakovic, Franz Josef Gassner, Christoph Ratswohl, Nadja Zaborsky, Stefan Rebhandl, Maria Schubert, Markus Steiner, Julia Christine Gutjahr, Lisa Pleyer, Alexander Egle, Tanja Nicole Hartmann, Richard Greil, Roland Geisberger
Publikováno v:
OncoImmunology, Vol 7, Iss 1 (2018)
While research on T cell exhaustion in context of cancer particularly focuses on CD8+ cytotoxic T cells, the role of inhibitory receptors on CD4+ T-helper cells have remained largely unexplored. TIGIT is a recently identified inhibitory receptor on T
Externí odkaz:
https://doaj.org/article/3efacdabf869402ea59e8d5004d73427
Autor:
Nadja Zaborsky, Claudia Holler, Roland Geisberger, Daniela Asslaber, Franz Josef Gassner, Viktoria Egger, Josephina Piñón-Hofbauer, Thomas Kocher, Tanja Nicole Hartmann, Richard Greil, Alexander Egle
Publikováno v:
Haematologica, Vol 100, Iss 8 (2015)
Externí odkaz:
https://doaj.org/article/0b4d4953d9284d25af19a34fe3c30c55
Autor:
Roland Geisberger, Richard Greil, Daniel Hebenstreit, Stephanie Blaimer, Kemal Catakovic, Nadja Zaborsky, Karina Spandl, Stefan Rebhandl, Maria Schubert, Franz Josef Gassner
Supplementary Figure and Table Legendslegends from Imprecision and DNA Break Repair Biased towards Incompatible End Joining in Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4deb817335550aeea74b08dbf508afbc
https://doi.org/10.1158/1541-7786.22513062.v1
https://doi.org/10.1158/1541-7786.22513062.v1
Autor:
Roland Geisberger, Richard Greil, Daniel Hebenstreit, Stephanie Blaimer, Kemal Catakovic, Nadja Zaborsky, Karina Spandl, Stefan Rebhandl, Maria Schubert, Franz Josef Gassner
Realtime RT-PCR on Lig1, XRCC1 and PARP1 on cDNA from CLL cells, B cells and Mec1 cells. Transcript levels are shown as relative abundance, normalized to the respective mean in B cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5a2561dbb5aa85cb7a4f303600cae61
https://doi.org/10.1158/1541-7786.22513065
https://doi.org/10.1158/1541-7786.22513065
Autor:
Roland Geisberger, Richard Greil, Daniel Hebenstreit, Stephanie Blaimer, Kemal Catakovic, Nadja Zaborsky, Karina Spandl, Stefan Rebhandl, Maria Schubert, Franz Josef Gassner
Supplementary table S1. Patient information. Supplementary table S2. Plasmid assay data for all inter- and intramolecular junctions in CLL and B cells. Supplementary table S3. Plasmid assay data for the most frequent intramolecular junctions in CLL a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21fd44aef26b6a23b3921e7c24c799e7
https://doi.org/10.1158/1541-7786.22513059.v1
https://doi.org/10.1158/1541-7786.22513059.v1
Autor:
Richard Greil, Roland Geisberger, Nadja Zaborsky, Stefanie Rauscher, Vanessa Tober, Stefan Rebhandl, Ekaterina Akimova, Claudia Arzt, Maria Schubert, Franz Josef Gassner
Publikováno v:
Nucleic Acids Research
Aberrant end joining of DNA double strand breaks leads to chromosomal rearrangements and to insertion of nuclear or mitochondrial DNA into breakpoints, which is commonly observed in cancer cells and constitutes a major threat to genome integrity. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89eee6b5ea4a3ea18e20fcafb8d03ec
https://doi.org/10.1093/nar/gkab051
https://doi.org/10.1093/nar/gkab051
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1094, p 1094 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1094
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1094
Chronic lymphocytic leukemia (CLL) is a very common and mostly incurable B-cell malignancy. Recent studies revealed high interpatient mutational heterogeneity and worsened therapy response and survival of patients with complex genomic aberrations. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4dd2036561c38364aa9939e45407961
https://www.mdpi.com/1422-0067/23/3/1094
https://www.mdpi.com/1422-0067/23/3/1094