Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Franz J. Zemp"'
Autor:
Amir Pozner, Li Li, Shiv Prakash Verma, Shuxin Wang, Jared J. Barrott, Mary L. Nelson, Jamie S. E. Yu, Gian Luca Negri, Shane Colborne, Christopher S. Hughes, Ju-Fen Zhu, Sydney L. Lambert, Lara S. Carroll, Kyllie Smith-Fry, Michael G. Stewart, Sarmishta Kannan, Bodrie Jensen, Cini M. John, Saif Sikdar, Hongrui Liu, Ngoc Ha Dang, Jennifer Bourdage, Jinxiu Li, Jeffery M. Vahrenkamp, Katelyn L. Mortenson, John S. Groundland, Rosanna Wustrack, Donna L. Senger, Franz J. Zemp, Douglas J. Mahoney, Jason Gertz, Xiaoyang Zhang, Alexander J. Lazar, Martin Hirst, Gregg B. Morin, Torsten O. Nielsen, Peter S. Shen, Kevin B. Jones
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The t(X,17) chromosomal translocation, generating the ASPSCR1::TFE3 fusion oncoprotein, is the singular genetic driver of alveolar soft part sarcoma (ASPS) and some Xp11-rearranged renal cell carcinomas (RCCs), frustrating efforts to identif
Externí odkaz:
https://doaj.org/article/22b004d19a254382bdb0a79d65c8bcf2
Autor:
Sahar Nasr, Lin Li, Mohammad Asad, Mahroo Moridi, Megan Wang, Franz J. Zemp, Douglas J. Mahoney, Edwin Wang
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105167- (2024)
Summary: Background: Tumour-infiltrating lymphocytes (TILs) are crucial for effective immune checkpoint blockade (ICB) therapy in solid tumours. However, ∼70% of these tumours exhibit poor lymphocyte infiltration, rendering ICB therapies less effec
Externí odkaz:
https://doaj.org/article/177976b0157f46519e49a5171c255ca9
Autor:
Ana Nikolic, Francesca Maule, Anna Bobyn, Katrina Ellestad, Seungil Paik, Sajid A. Marhon, Parinaz Mehdipour, Xueqing Lun, Huey-Miin Chen, Claire Mallard, Alexander J. Hay, Michael J. Johnston, Christopher J. Gafuik, Franz J. Zemp, Yaoqing Shen, Nicoletta Ninkovic, Katalin Osz, Elodie Labit, N. Daniel Berger, Duncan K. Brownsey, John J. Kelly, Jeff Biernaskie, Peter B. Dirks, Darren J. Derksen, Steven J. M. Jones, Donna L. Senger, Jennifer A. Chan, Douglas J. Mahoney, Daniel D. De Carvalho, Marco Gallo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Self-renewal is a crucial property of glioblastoma cells that is enabled by the choreographed functions of chromatin regulators and transcription factors. Identifying targetable epigenetic mechanisms of self-renewal could therefore represent
Externí odkaz:
https://doaj.org/article/028fa80da48448499589471060a20e19
Autor:
Kayla L. Marritt, Karys M. Hildebrand, Kurt N. Hildebrand, Arvind K. Singla, Franz J. Zemp, Douglas J. Mahoney, Frank R. Jirik, Michael J. Monument
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionSoft tissue sarcomas (STS) are highly metastatic, connective-tissue lineage solid cancers. Immunologically, sarcomas are frequently characterized by a paucity of tumor infiltrating lymphocytes and an immune suppressive microenvironment. A
Externí odkaz:
https://doaj.org/article/e8e244d2e9ed4365ae8f75807960f42a
Autor:
Dae-Sun Kim, Himika Dastidar, Chunfen Zhang, Franz J. Zemp, Keith Lau, Matthias Ernst, Andrea Rakic, Saif Sikdar, Jahanara Rajwani, Victor Naumenko, Dale R. Balce, Ben W. Ewanchuk, Pankaj Tailor, Robin M. Yates, Craig Jenne, Chris Gafuik, Douglas J. Mahoney
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Oncolytic viruses (OV) and second mitochondrial activator of caspase (Smac)-mimetic compounds (SMC) synergistically kill cancer cells directly. Here, the authors show that SMC and OV therapies combination also synergize in vivo by promoting anticance
Externí odkaz:
https://doaj.org/article/f1edf28f5df34c7d87c29319c84877f7
Autor:
Dae-Sun Kim, Himika Dastidar, Chunfen Zhang, Franz J. Zemp, Keith Lau, Matthias Ernst, Andrea Rakic, Saif Sikdar, Jahanara Rajwani, Victor Naumenko, Dale R. Balce, Ben W. Ewanchuk, Pankaj Tailor, Robin M. Yates, Craig Jenne, Chris Gafuik, Douglas J. Mahoney
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The originally published version of this article contained an error in the spelling of the author Pankaj Tailor, which was incorrectly given as Pankaj Taylor. This has now been corrected in both the PDF and HTML versions of the article.
Externí odkaz:
https://doaj.org/article/01f58fd455364410985bc25d2d498a40
Autor:
V. Wee Yong, Stephen M. Robbins, Donna L. Senger, Wu Wei, Franz J. Zemp, Reza Mirzaei, Susobhan Sarkar
Oncogenic signaling by NOTCH is elevated in brain tumor-initiating cells (BTIC) in malignant glioma, but the mechanism of its activation is unknown. Here we provide evidence that tenascin-C (TNC), an extracellular matrix protein prominent in malignan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6b1f23ff7e1306e2ed8a74ee022bb01
https://doi.org/10.1158/0008-5472.c.6508760.v1
https://doi.org/10.1158/0008-5472.c.6508760.v1
Autor:
V. Wee Yong, Stephen M. Robbins, Donna L. Senger, Wu Wei, Franz J. Zemp, Reza Mirzaei, Susobhan Sarkar
This supplementary data of microarray information contains results that support the tenascin C to notch pathway highlighted in this manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19664f8f2c73dfafdb3efa14a760b9ba
https://doi.org/10.1158/0008-5472.22413578.v1
https://doi.org/10.1158/0008-5472.22413578.v1
Autor:
V. Wee Yong, Stephen M. Robbins, Donna L. Senger, Wu Wei, Franz J. Zemp, Reza Mirzaei, Susobhan Sarkar
Supplementary data of microarray information contains results that support the tenascin C to notch pathway highlighted in this manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6841685e6035d5852db3b0960b0624ec
https://doi.org/10.1158/0008-5472.22413575.v1
https://doi.org/10.1158/0008-5472.22413575.v1
Autor:
V. Wee Yong, Stephen M. Robbins, Donna L. Senger, Wu Wei, Franz J. Zemp, Reza Mirzaei, Susobhan Sarkar
Supplementary Figure S1:TNC expression in mice implanted with human BTIC. Supplementary Figure S2: TNC expression, BTIC growth and invasiveness in orthotopic BT53M xenograft. Supplementary Figure S3: Tumor growth in orthotopic BTIC 53M xenograft impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ccb1ec9dfc7025881204f0c7465a1d
https://doi.org/10.1158/0008-5472.22413581.v1
https://doi.org/10.1158/0008-5472.22413581.v1