Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Frantisek, Mrazek"'
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Coeliac disease (CD) is an autoimmune disorder caused by the ingestion of gluten-containing grains. One of the prerequisites for the development of the disease is the presence of specific combinations of HLA alleles at the DQA1 and DQB1 loci. The HLA
Externí odkaz:
https://doaj.org/article/901c1d4a5374495c90aa7bf562ba5941
Autor:
Frantisek Mrazek
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Numerous associations of HLA variants with susceptibility to diseases, namely, those with an immunopathological component, have been described to date. The strongest HLA associations were incorporated into the standard algorithms for the diagnostics.
Externí odkaz:
https://doaj.org/article/491de64325e242d0aaec32094f89ae6d
Autor:
Anna Petrackova, Andrea Smrzova, Petr Gajdos, Marketa Schubertova, Petra Schneiderova, Pavel Kromer, Vaclav Snasel, Martina Skacelova, Frantisek Mrazek, Josef Zadrazil, Pavel Horak, Eva Kriegova
Publikováno v:
Clinical Proteomics, Vol 14, Iss 1, Pp 1-15 (2017)
Abstract Background Systemic lupus erythematosus (SLE) is a remarkably heterogeneous autoimmune disease. Despite tremendous efforts, our knowledge of serum protein patterns in severe SLE phenotypes is still limited. We investigated the serum protein
Externí odkaz:
https://doaj.org/article/f2cd299f5d83405981961bc58eafaf81
Cross-Disease Innate Gene Signature: Emerging Diversity and Abundance in RA Comparing to SLE and SSc
Autor:
Anna Petrackova, Pavel Horak, Martin Radvansky, Martina Skacelova, Regina Fillerova, Milos Kudelka, Andrea Smrzova, Frantisek Mrazek, Eva Kriegova
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Overactivation of the innate immune system together with the impaired downstream pathway of type I interferon-responding genes is a hallmark of rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and systemic sclerosis (SSc). To date, limi
Externí odkaz:
https://doaj.org/article/5178e94c9f9840feae72344f1f0ddd59
Publikováno v:
HLA.
Autor:
Elisa Laura Lahtela, Annika Wolin, Verneri Anttila, Martin Petrek, Johan Grunewald, Coline H. M. van Moorsel, Anders Eklund, Jan C. Grutters, Vitezslav Kolek, Frantisek Mrazek, Amit Kishore, Leonid Padyukov, Anne Pietinalho, Marcus Ronninger, Mikko Seppänen, Olof Selroos, Marja-Liisa Lokki
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Sarcoidosis is a multiorgan inflammatory disorder with heritability estimates up to 66%. Previous studies have shown the major histocompatibility complex (MHC) region to be associated with sarcoidosis, suggesting a functional role for antigen-present
Externí odkaz:
https://doaj.org/article/4465b9911744458ea9b4b80def059783
Autor:
Adam, Kuba, Ludek, Raida, Svetlana, Brychtova, Patrik, Flodr, Frantisek, Mrazek, Eva, Kriegova, Edgar, Faber, Tomas, Papajik
Publikováno v:
Transplant immunology. 76
Lower gastrointestinal (GI) graft versus host disease (GVHD) represents a severe complication in allogeneic hematopoietic stem cell transplant (HSCT) recipients with high rates of transplant-related mortality. Deregulated innate immunity reactions ar
Autor:
Adam Kuba, Ludek Raida, Patrik Flodr, Frantisek Mrazek, Eva Kriegova, Tomáš Papajík, Jiri Minarik
Publikováno v:
Blood. 140:7643-7644
Autor:
Tomas Papajik, Eva Kriegova, Frantisek Mrazek, Tomáš Fürst, Jana Furstova, Edgar Faber, Ludek Raida, Katerina Langova, Adam Kuba, Petra Schneiderova
Publikováno v:
Annals of Hematology. 99:609-618
Graft-versus-host disease (GVHD) represents a significant cause of mortality after allogeneic hematopoietic stem cell transplantation (HSCT). NF-kB system is a master regulator of innate immunity responses. It controls the expression of various cytok
Autor:
Veronika Sekerova, Daniela Subrtova, Frantisek Mrazek, Agata Gibejova, Vitezslav Kolek, Roland M. du Bois, Martin Petrek
Publikováno v:
Mediators of Inflammation, Vol 12, Iss 4, Pp 215-220 (2003)
Background: CC chemokine ligand (CCL)5 and its receptor CCR5 contribute to leukocyte migration into lungs of patients with diffuse lung diseases (DLD). Pharmacological regulation of CCL5 and CCR5 expression was therefore explored in bronchoalveolar c
Externí odkaz:
https://doaj.org/article/c223805f1d224516a9f9f1ba5304fb2c