Výsledky vyhledávání - "Frantiescoli A, Dimer"

Akademický článek

LC-MS/MS method applied to preclinical pharmacokinetic investigation of olanzapine-loaded lipid-core nanocapsules

Autor: Frantiescoli A. Dimer, Maiara C. Pigatto, Adriana R. Pohlmann, Teresa Dalla Costa, Silvia S. Guterres

Publikováno v: Química Nova, Vol 37, Iss 8, Pp 1371-1376 (2014)

In spite of different methods reported in the literature to determine olanzapine in biological fluids, all of them used high volumes of plasma. Therefore, the purpose of this paper was to develop an LC-MS/MS method using small plasma volume (0.1 mL)

Externí odkaz: https://doaj.org/article/c0476a59ae5742fd947a82202bb95e1b

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Akademický článek

Formulation and characterization of poloxamer 407®: thermoreversible gel containing polymeric microparticles and hyaluronic acid

Autor: Gabriela Garrastazu Pereira, Frantiescoli Anversa Dimer, Sílvia Stanisçuaki Guterres, Carolina Pereira Kechinski, Jonas Eichelberger Granada, Nilo Sérgio Medeiros Cardozo

Publikováno v: Química Nova, Vol 36, Iss 8, Pp 1121-1125 (2013)

The influence of the composition and preparation method on the sol-gel transition temperature (Tsol-gel) and rheological response of poloxamer-based formulations was determined. Manual and more complex mechanical stirring were found to provide simila

Externí odkaz: https://doaj.org/article/3198adab073346238acbc067f3fb2ec8

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Akademický článek

Impactos da nanotecnologia na saúde: produção de medicamentos

Autor: Frantiescoli A. Dimer, Rossana B. Friedrich, Ruy C. R. Beck, Sílvia S. Guterres, Adriana R. Pohlmann

Publikováno v: Química Nova, Vol 36, Iss 10, Pp 1520-1526 (2013)

Several studies have described the benefits of nanoscience and nanotechnology (N&N) in different sectors such as agriculture, energy, environmental preservation, and public health. The rapid evolution of N&N can be shown through a panoramic analysis

Externí odkaz: https://doaj.org/article/9bf8cbedc61e4e17b497ef4a2183a0b4

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PLGA nanocapsules improve the delivery of clarithromycin to kill intracellular Staphylococcus aureus and Mycobacterium abscessus

Autor: Claus-Michael Lehr, Adriely Goes, Jennifer Herrmann, Frantiescoli Anversa Dimer, Cristiane de Souza Carvalho-Wodarz, Markus Bischoff, Viktoria Schmitt, Patrick Couvreur, Chiara De Rossi, Linda Pätzold, Katarina Cirnski, Nadia Abed, Rolf Müller

Publikováno v: Nanomedicine : nanotechnology, biology, and medicine

Drug delivery systems are promising for targeting antibiotics directly to infected tissues. To reach intracellular Staphylococcus aureus and Mycobacterium abscessus, we encapsulated clarithromycin in PLGA nanocapsules, suitable for aerosol delivery b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11eca62af633bbb5565c9e661c1873f7
https://hdl.handle.net/10033/622059

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Inhalable resveratrol microparticles produced by vibrational atomization spray drying for treating pulmonary arterial hypertension

Autor: Frantiescoli Anversa Dimer, Manoel Ortiz, Silvia Stanisçuaski Guterres, Adriana Raffin Pohlmann

Publikováno v: Journal of Drug Delivery Science and Technology. 29:152-158

The rare disorder pulmonary arterial hypertension is characterized by elevated pulmonary arterial pressure and right heart failure. Currently, the treatments have improved, but a cure has not yet been discovered. In this study, we developed a new for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d39ff2b704f52651a51aad31495a63ad
https://doi.org/10.1016/j.jddst.2015.07.008

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Mucoadhesive Amphiphilic Methacrylic Copolymer-Functionalized Poly(ε-caprolactone) Nanocapsules for Nose-to-Brain Delivery of Olanzapine

Autor: Francisco N. Fonseca, Maria Palmira Daflon Gremião, Silvia Stanisçuaski Guterres, Flávia Chiva Carvalho, Frantiescoli Anversa Dimer, Andresa Heemann Betti, Adriana Raffin Pohlmann, Marli Luiza Tebaldi, Stela Maris Kuze Rates

Publikováno v: Journal of Biomedical Nanotechnology. 11:1472-1481

Nose-to-brain drug delivery has been proposed to overcome the low absorption of drugs in central nervous system due to the absence of brain-blood barrier in the olfactory nerve pathway. However, the presence of a mucus layer and quick clearance limit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::072be7efc2907cf994cdc645babce4b2
https://doi.org/10.1166/jbn.2015.2078

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Nanoencapsulation of Tacrolimus in Lipid-Core Nanocapsules Showed Similar Immunosuppressive Activity After Oral and Intraperitoneal Administrations

Autor: Adriana Raffin Pohlmann, Ruy Carlos Ruver Beck, Rossana B. Friedrich, S.S. Guterres, Frantiescoli Anversa Dimer

Publikováno v: Journal of Biomedical Nanotechnology. 10:1599-1609

Tacrolimus is widely used in the prophylaxis of solid-organ transplant rejection. Several studies have reported that tacrolimus has variable and poor bioavailability after oral administration, apart from adverse effects such as gastrointestinal disor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c16bfa7b978004d3e16c7afb64e33c
https://doi.org/10.1166/jbn.2014.1842

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Impactos da nanotecnologia na saúde: produção de medicamentos

Autor: Ruy Carlos Ruver Beck, Frantiescoli Anversa Dimer, Rossana B. Friedrich, Silvia Stanisçuaski Guterres, Adriana Raffin Pohlmann

Publikováno v: Química Nova, Vol 36, Iss 10, Pp 1520-1526 (2013)
Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
Química Nova v.36 n.10 2013
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Química Nova, Volume: 36, Issue: 10, Pages: 1520-1526, Published: 2013

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5e026501edbffac8caf1c7a0a03188
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422013001000007&lng=en&tlng=en

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Nanoencapsulation Improves Relative Bioavailability and Antipsychotic Effect of Olanzapine in Rats

Autor: Rates Mk, S.S. Guterres, Frantiescoli Anversa Dimer, Marilise Escobar Burger, Maiara Cássia Pigatto, Dalla Costa T, Camila Simonetti Pase, Boque Ca, Katiane Roversi, Adriana Raffin Pohlmann

Publikováno v: Journal of biomedical nanotechnology. 11(8)

This study aimed to investigate the pharmacokinetics, tissue distribution and antipsychotic activity of olanzapine administered as free drug (OLA-FREE) or loaded into lipid-core nanocapsules (OLA-LNC). OLA-LNC were successfully developed with a parti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf37502c7b6c44e4ea2338dc2ac62cd
https://pubmed.ncbi.nlm.nih.gov/26295148

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Inhalable Clarithromycin Microparticles for Treatment of Respiratory Infections

Autor: Frantiescoli Anversa Dimer, Cristiane de Souza Carvalho-Wodarz, Claus-Michael Lehr, Rolf W. Hartmann, Jörg Haupenthal

Publikováno v: Pharmaceutical research. 32(12)

The aim of this work was to develop clarithromycin microparticles (CLARI-MP) and evaluate their aerodynamic behavior, safety in bronchial cells and anti-bacterial efficacy. Microparticles containing clarithromycin were prepared as dry powder carrier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf3c8ec7bb2d7332c805b6bb8294f2f
https://pubmed.ncbi.nlm.nih.gov/26113237

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