Zobrazeno 1 - 10
of 79
pro vyhledávání: '"František Vyskočil"'
Publikováno v:
Physiological Research. :185-188
M1-muscarinic acetylcholine (ACh) receptors (M1R) were directly demonstrated immunocytochemically in electronmicroscopic images of rat diaphragm neuromuscular junctions (NMJ). Specific electron-dense granules were located at presynaptic nerve ending
Publikováno v:
Physiological Research. :763-784
There are two principal mechanisms of acetylcholine (ACh) release from the resting motor nerve terminal: quantal and nonquantal (NQR); the former being only a small fraction of the total, at least at rest. In the present article we summarize basic re
Publikováno v:
Journal of Neurochemistry. 102:2110-2117
Nitric oxide (NO), previously demonstrated to participate in the regulation of the resting membrane potential in skeletal muscles via muscarinic receptors, also regulates non-quantal acetylcholine (ACh) secretion from rat motor nerve endings. Non-qua
Autor:
František Vyskočil, Lev G. Magazanik, D. V. Samigullin, Ella A. Bukharaeva, Eugeny E. Nikolsky
Publikováno v:
The Journal of Physiology. 560:77-88
Different receptors located on the presynaptic membrane may modulate transmitter release (Ciani & Edwards, 1963; Miyamoto, 1977; Steinbach & Stevens, 1979; Starke, 1989; Bowman et al. 1990; Miller, 1998; MacDermott et al. 1999). One intriguing proble
Autor:
František Vyskočil
Publikováno v:
Neurochemical Research. 28:575-585
Resting non-quantal acetylcholine (ACh) and probably glutamate (Glu) release from nerve endings activates M1- and NMDA receptor-mediated Ca2+ entry into the sarcoplasm with following activation of NOS and production of NO. This is a trophic message f
Publikováno v:
Journal of Neurochemistry. 63:662-670
The membrane-bound or solubilized melatonin receptors were treated with protein-modifying agents under specific conditions and then assayed for 125I-melatonin binding in order to obtain information on amino acids present in the ligand binding domain.
Autor:
Alexander R. Mukhitov, Evgeny E. Nikolsky, A. I. Malomouzh, S. E. Proskurina, František Vyskočil
Publikováno v:
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. 459
Publikováno v:
Neuroscience Research. 39:287-292
A new comparative characteristic of endplate microphysiology has been introduced. It is the feasibility of receptors to become desensitised as demonstrated on two frog species, Rana temporaria and Rana ridibunda: the decay times (tau(MEPC)) of single
Publikováno v:
Neurochemical Research. 26:891-897
The effects of carbachol (CCh) on the frequency (f) of the miniature endplate potentials were tested at temperatures between 5 and 30°C. Higher CCh concentrations, 1 × 10−5 and 5 × 10−6 M, reduced the f to 60% and the temperature dependence wa
Publikováno v:
Neuroscience Research. 33:81-86
The membrane potentials of denervated muscle fibres of the rat diaphragm kept in a tissue culture medium are depolarized by about 8-10 mV (10-12%) within 3 h after denervation. This early post-denervation depolarization (EPD) is substantially reduced